Abstract: Provided are compositions and processes that utilize genomic regions that are differentially methylated between a mother and her fetus to separate, isolate or enrich fetal nucleic acid from a maternal sample. The compositions and processes described herein are particularly useful for non-invasive prenatal diagnostics, including the detection of chromosomal aneuploidies.
Type:
Application
Filed:
March 8, 2013
Publication date:
November 7, 2013
Applicants:
SEQUENOM CENTER FOR MOLECULAR MEDICINE, SEQUENOM, INC.
Abstract: Provided are compositions and processes that utilize genomic regions that are differentially methylated between a mother and her fetus to separate, isolate or enrich fetal nucleic acid from a maternal sample. The compositions and processes described herein are particularly useful for non-invasive prenatal diagnostics, including the detection of chromosomal aneuplodies.
Type:
Application
Filed:
March 18, 2010
Publication date:
October 28, 2010
Applicants:
SEQUENOM, INC., SEQUENOM CENTER FOR MOLECULAR MEDICINE
Inventors:
Mathias Ehrich, Anders Olof Herman Nygren
Abstract: Provided are compositions and processes that utilize genomic regions differentially methylated between a mother and her fetus to separate, isolate or enrich fetal nucleic acid from a maternal sample. The compositions and processes described herein are useful for non-invasive prenatal diagnostics, including the detection of chromosomal aneuplodies.
Type:
Application
Filed:
September 16, 2009
Publication date:
April 29, 2010
Applicants:
SEQUENOM, INC., SEQUENOM CENTER FOR MOLECULAR MEDICINE
Inventors:
Mathias Ehrich, Anders Olof Herman Nygren