Abstract: Disclosed is a family of intranasal spray dispensers for administering uniform low doses of desmopressin so as to achieve safe antidiuresis in human patients. The dispensers of the invention may be used in the treatment of nocturia, primary nocturnal enuresis, incontinence, urinary frequency, diabetes insipidus, or any disease or syndrome where desmopressin therapy is useful or where safe temporary suppression of urine production may lead to beneficial health effects or increased convenience in voiding control.
Abstract: The invention provides methods and compositions for use of desmopressin in combination with a beta-3-adrenergic receptor agonist. The methods and compositions are useful in the treatment of nocturia and other urinary frequency disorders.
Abstract: The invention provides methods and compositions for use of desmopressin in combination with an alpha-adrenergic receptor antagonist. The methods and compositions are useful in the treatment of nocturia and other urinary frequency disorders.
Type:
Grant
Filed:
November 19, 2015
Date of Patent:
May 14, 2019
Assignee:
Serenity Pharmaceuticals, LLC
Inventors:
Seymour H. Fein, Linda Cheng, Maria Cheng, Samuel Herschkowitz
Abstract: The invention provides methods and compositions for use of desmopressin in combination with a 5-alpha reductase inhibitor. The methods and compositions are useful in the treatment of nocturia and other urinary frequency disorders.
Type:
Grant
Filed:
July 23, 2014
Date of Patent:
March 27, 2018
Assignee:
Serenity Pharmaceuticals, LLC
Inventors:
Seymour H. Fein, Linda Cheng, Maria Cheng, Samuel Herschkowitz
Abstract: The invention provides methods and compositions for use of desmopressin in combination with a beta-3-adrenergic receptor agonist. The methods and compositions are useful in the treatment of nocturia and other urinary frequency disorders.