Patents Assigned to Serentrix, LLC.
  • TRPV1 vanilloid receptor antagonists with a bicyclic portion
    Patent number: 9216975
    Abstract: The invention discloses compounds of formula I wherein Y is a group of formula A, B, C, D, or E: and W, Q, n, R1, R2, R3, U1-U5, J and K have the meanings given in the description. The compounds of formula I are TRPV1 antagonists and are useful as active ingredients of pharmaceutical compositions for the treatment of pain and other conditions ameliorated by the inhibition of the vanilloid receptor TRPV1.
    Type: Grant
    Filed: December 22, 2010
    Date of Patent: December 22, 2015
    Assignee: Serentrix, LLC.
    Inventors: Mauro Napoletano, Marcello Trevisani, Maria Giovanna Pavani, Francesca Fruttarolo