Patents Assigned to Serologicals, Inc.
  • Purines and pyrimidines linked to a quencher
    Patent number: 6531581
    Abstract: Compounds are described comprising purines substituted at the C-8 position and pyrimidines substituted at the C-4 position with a linker and quencher. These compounds, when incorporated into hairpin oligonucleotides quench the fluorescence of fluorophores linked to the 5′-terminus of the oligonucleotide. These nucleotide-quencher compounds are also easily incorporated into oligonucleotides using conventional or automated oligonucleotide synthetic techniques.
    Type: Grant
    Filed: October 26, 2000
    Date of Patent: March 11, 2003
    Assignee: Serologicals, Inc.
    Inventors: Glenn Nardone, Irena Nazarenko, Jila Boal