Patents Assigned to SGX Pharmaceuticals, Inc.
  • Bicyclic triazoles as protein kinase modulators
    Patent number: 8507489
    Abstract: The present disclosure provides bicyclic triazole protein kinase modulators and methods of using these compounds to treat diseases mediated by kinase activity.
    Type: Grant
    Filed: October 18, 2007
    Date of Patent: August 13, 2013
    Assignee: SGX Pharmaceuticals, Inc.
    Inventors: Pierre-Yves Bounaud, Christopher Ronald Smith, Elizabeth Anne Jefferson
  • Fused ring heterocycle kinase modulators
    Patent number: 8268994
    Abstract: The present invention provides novel fused ring heterocycle kinase modulators and methods of using the novel fused ring heterocycle kinase modulators to treat diseases mediated by kinase activity.
    Type: Grant
    Filed: August 11, 2009
    Date of Patent: September 18, 2012
    Assignee: SGX Pharmaceuticals, Inc.
    Inventors: William D. Arnold, Pierre Bounaud, Chixu Chen, Brian Eastman, Andreas Gosberg, Stefan N. Gradl, Stephanie Hopkins, Zhe Li, Ian McDonald, Paul A. Sprengeler, Ruo W. Steensma, Mark E. Wilson
  • Fused ring heterocycle kinase modulators
    Patent number: 8242280
    Abstract: The present invention provides fused ring heterocycles as kinase modulators, pharmaceutical compositions containing these modulators, and methods of using these modulators to treat diseases mediated by kinase activity.
    Type: Grant
    Filed: April 10, 2008
    Date of Patent: August 14, 2012
    Assignee: SGX Pharmaceuticals, Inc.
    Inventors: Chixu Chen, Brian Eastman, Andreas Gosberg, Stefan N. Gradl, Gavin Hirst, Stephanie Hopkins, Khanh Thi Tuong Nguyen, Richard Pracitto, Paul E. Sprengeler, Ruo W. Steensma
  • Substituted pyrrolopyridines and pyrazolopyridines as kinase modulators
    Patent number: 8158647
    Abstract: Provided herein are substituted pyrrolopyridine heterocycles and substituted pyrazolopyridine heterocycles, pharmaceutical compositions comprising said heterocycles and methods of using said heterocycles in the treatment of disease. The heterocycles disclosed herein function as kinase modulators and have utility in the treatment of diseases such as cancer, allergy, asthma, inflammation, obstructive airway disease, autoimmune diseases, metabolic disease, infection, CNS disease, brain tumor, obesity, asthma, hematological disorder, degenerative neural disease, cardiovascular disease, or disease associated with angiogenesis, neovascularization, or vasculogenesis.
    Type: Grant
    Filed: May 29, 2008
    Date of Patent: April 17, 2012
    Assignee: SGX Pharmaceuticals, Inc.
    Inventors: Jeffrey M. Blaney, Andreas Gosberg, Stefan N. Gradl, Gavin Hirst, Stephanie A. Hopkins, Paul A. Sprengeler, Ruo W. Steensma, Johnny Uy
  • Triazolopyridazine protein kinase modulators
    Patent number: 8071581
    Abstract: The present disclosure relates to triazolopyridazine protein kinase modulators of Formula (I), methods of using these compounds to treat diseases mediated by kinase activity.
    Type: Grant
    Filed: October 18, 2007
    Date of Patent: December 6, 2011
    Assignee: SGX Pharmaceuticals, Inc.
    Inventors: Christopher Ronald Smith, Pierre-Yves Bounaud, Elizabeth Anne Jefferson, Patrick S. Lee, Eduardo Torres
  • Pyrimidinyl-thiophene kinase modulators
    Patent number: 7977481
    Abstract: The present invention provides novel pyrimidinyl-thiophene kinase modulators and methods of using the novel pyrimidinyl-thiophene kinase modulators to treat diseases mediated by kinase activity.
    Type: Grant
    Filed: August 6, 2010
    Date of Patent: July 12, 2011
    Assignee: SGX Pharmaceuticals, Inc.
    Inventors: William D. Arnold, Chixu Chen, Stefan N. Gradl, Stephanie Hopkins, Ruo W. Steensma, Masaki Tomimoto, Mark E. Wilson
  • Pyrrolo-pyridine kinase modulators
    Patent number: 7906648
    Abstract: The present invention provides novel pyrrolo-pyridine kinase modulators and methods of using the novel pyrrolo-pyridine kinase modulators to treat diseases mediated by kinase activity.
    Type: Grant
    Filed: July 10, 2009
    Date of Patent: March 15, 2011
    Assignee: SGX Pharmaceuticals, Inc.
    Inventors: William D. Arnold, Pierre Bounaud, Andreas Gosberg, Zhe Li, Ian McDonald, Ruo W. Steensma, Mark E. Wilson
  • Fused ring heterocycle kinase modulators
    Patent number: 7829558
    Abstract: The present invention provides novel fused ring heterocycle kinase modulators and methods of using the novel fused ring heterocycle kinase modulators to treat diseases mediated by kinase activity.
    Type: Grant
    Filed: September 22, 2008
    Date of Patent: November 9, 2010
    Assignee: SGX Pharmaceuticals, Inc.
    Inventors: William D. Arnold, Andreas Gosberg, Zhe Li, Ruo W. Steensma, Mark E. Wilson
  • Pyrimidinyl-thiophene kinase modulators
    Patent number: 7803806
    Abstract: The present invention provides novel pyrimidinyl-thiophene kinase modulators and methods of using the novel pyrimidinyl-thiophene kinase modulators to treat diseases mediated by kinase activity.
    Type: Grant
    Filed: November 2, 2006
    Date of Patent: September 28, 2010
    Assignee: SGX Pharmaceuticals, Inc.
    Inventors: William D. Arnold, Chixu Chen, Stefan N. Gradl, Stephanie A. Hopkins, Ruo W. Steensma, Masaki Tomimoto, Mark E. Wilson
  • BICYCLIC PYRAZOLO PROTEIN KINASE MODULATORS
    Publication number: 20100179190
    Abstract: The present invention provides novel bicyclic pyrazolo kinase modulators and methods of using the novel bicyclic pyrazolo kinase modulators to treat diseases mediated by kinase activity.
    Type: Application
    Filed: November 14, 2008
    Publication date: July 15, 2010
    Applicant: SGX PHARMACEUTICALS, INC.
    Inventors: Pierre-Yves Bounaud, Andrew Vaino
  • Pyrrolo-pyridine kinase modulators
    Patent number: 7709645
    Abstract: The present invention provides novel pyrrolo-pyridine kinase modulators and methods of using the novel pyrrolo-pyridine kinase modulators to treat diseases mediated by kinase activity.
    Type: Grant
    Filed: April 10, 2007
    Date of Patent: May 4, 2010
    Assignee: SGX Pharmaceuticals, Inc.
    Inventors: William D Arnold, Pierre Bounaud, Chixu Chen, Brian Eastman, Andreas Gosberg, Stefan N. Gradl, Stephanie Hopkins, Zhe Li, Ian McDonald, Paul A. Sprengeler, Ruo W. Steensma, Mark E. Wilson
  • Fused ring heterocycle kinase modulators
    Patent number: 7626021
    Abstract: The present invention provides novel fused ring heterocycle kinase modulators and methods of using the novel fused ring heterocycle kinase modulators to treat diseases mediated by kinase activity.
    Type: Grant
    Filed: April 10, 2007
    Date of Patent: December 1, 2009
    Assignee: SGX Pharmaceuticals, Inc.
    Inventors: William D. Arnold, Pierre Bounaud, Chixu Chen, Brian Eastman, Andreas Gosberg, Stefan N. Gradl, Stephanie Hopkins, Zhe Li, Ian McDonald, Paul A. Sprengeler, Ruo W. Steensma, Mark E. Wilson
  • Pyrrolo-pyridine kinase modulators
    Patent number: 7601839
    Abstract: The present invention provides novel pyrrolo-pyridine kinase modulators and methods of using the novel pyrrolo-pyridine kinase modulators to treat diseases mediated by kinase activity.
    Type: Grant
    Filed: February 29, 2008
    Date of Patent: October 13, 2009
    Assignee: SGX Pharmaceuticals Inc.
    Inventors: William D. Arnold, Pierre-Yves Bounaud, Andreas Gosberg, Zhe Li Bounaud, Ian McDonald, Ruo W. Steensma, Mark E. Wilson
  • Pyrrolo-pyridine kinase modulators
    Patent number: 7582637
    Abstract: The present invention provides novel pyrrolo-pyridine kinase modulators and methods of using the novel pyrrolo-pyridine kinase modulators to treat diseases mediated by kinase activity.
    Type: Grant
    Filed: February 29, 2008
    Date of Patent: September 1, 2009
    Assignee: SGX Pharmaceuticals, Inc.
    Inventors: William D. Arnold, Pierre-Yves Bounaud, Andreas Gosberg, Zhe Li Bounaud, Ian McDonald, Ruo W. Steensma, Mark E. Wilson
  • FUSED RING HETEROCYCLE KINASE MODULATORS
    Publication number: 20090203687
    Abstract: The present invention provides novel fused ring heterocycle kinase modulators and methods of using the novel fused ring heterocycle kinase modulators to treat diseases mediated by kinase activity.
    Type: Application
    Filed: September 22, 2008
    Publication date: August 13, 2009
    Applicant: SGX Pharmaceuticals, Inc.
    Inventors: William D. Arnold, Andreas Gosberg, Zhe Li, Ruo W. Steemsma, Mark E. Wilson
  • HETEROCYCLIC KINASE MODULATORS
    Publication number: 20090156594
    Abstract: The present disclosure provides heterocyclic protein kinase modulators and methods of using these compounds to treat diseases mediated by kinase activity.
    Type: Application
    Filed: May 21, 2008
    Publication date: June 18, 2009
    Applicant: SGX Pharmaceuticals, Inc.
    Inventors: Pierre-Yves Bounaud, Christopher Ronald Smith, Elizabeth A. Jefferson, Jorg Hendle, Patrick S. Lee, Angelina Marie Thayer, Gavin Charles Hirst
  • PYRROLO-PYRIDINE KINASE MODULATIORS
    Publication number: 20090143352
    Abstract: The present invention provides novel pyrrolo-pyridine kinase modulators and methods of using the novel pyrrolo-pyridine kinase modulators to treat diseases mediated by kinase activity.
    Type: Application
    Filed: April 10, 2007
    Publication date: June 4, 2009
    Applicant: SGX Pharmaceuticals, Inc.
    Inventors: William D. Arnold, Pierre Bounaud, Chixu Chen, Brian Eastman, Andreas Gosberg, Stefan N. Gradl, Stephanie Hopkins, Zhe Li, Ian McDonald, Paul A. Sprengeler, Ruo W. Steensma, Mark E. Wilson
  • Bicyclic pyrazolo protein kinase modulators
    Patent number: 7473783
    Abstract: The present invention provides novel bicyclic pyrazolo kinase modulators and methods of using the novel bicyclic pyrazolo kinase modulators to treat diseases mediated by kinase activity.
    Type: Grant
    Filed: December 17, 2004
    Date of Patent: January 6, 2009
    Assignee: SGX Pharmaceuticals, Inc.
    Inventors: Pierre-Yves Bounaud, Andrew Vaino
  • PYRROLO-PYRIDINE KINASE MODULATORS
    Publication number: 20090005378
    Abstract: The present invention provides novel pyrrolo-pyridine kinase modulators and methods of using the novel pyrrolo-pyridine kinase modulators to treat diseases mediated by kinase activity.
    Type: Application
    Filed: February 29, 2008
    Publication date: January 1, 2009
    Applicant: SGX Pharmaceuticals, Inc.
    Inventors: William D. Arnold, Pierre-Yves Bounaud, Andreas Gosberg, Zhe Li Bounaud, Ian McDonald, Ruo W. Steensma, Mark E. Wilson
  • SUBSTITUTED PYRROLOPYRIDINES AND PYRAZOLOPYRIDINES AS KINASE MODULATORS
    Publication number: 20090005356
    Abstract: Provided herein are substituted pyrrolopyridine heterocycles and substituted pyrazolopyridine heterocycles, pharmaceutical compositions comprising said heterocycles and methods of using said heterocycles in the treatment of disease. The heterocycles disclosed herein function as kinase modulators and have utility in the treatment of diseases such as cancer, allergy, asthma, inflammation, obstructive airway disease, autoimmune diseases, metabolic disease, infection, CNS disease, brain tumor, obesity, asthma, hematological disorder, degenerative neural disease, cardiovascular disease, or disease associated with angiogenesis, neovascularization, or vasculogenesis.
    Type: Application
    Filed: May 29, 2008
    Publication date: January 1, 2009
    Applicant: SGX Pharmaceuticals, Inc.
    Inventors: Jeffrey M. Blaney, Andreas Gosberg, Stefan N. Gradl, Gavin Hirst, Stephanie A. Hopkins, Paul A. Sprengeler, Ruo W. Steensma, Johnny Uy