Patents Assigned to SHANGHAI INSTITUTE OF BIOLOGICAL PRODUCTS CO., LTD.
  • Anti-HER3 humanized monoclonal antibody
    Patent number: 11965037
    Abstract: Provided is an anti-HER3 humanized monoclonal antibody. The antibody binds HER3 antigen, has high affinity and biological activity and low immunogenicity, and is stable in structure. The antibody can be used for preparing drugs for preventing or treating HER3-related diseases.
    Type: Grant
    Filed: July 17, 2019
    Date of Patent: April 23, 2024
    Assignee: SHANGHAI INSTITUTE OF BIOLOGICAL PRODUCTS CO., LTD.
    Inventors: Aidong Qu, Hongyuan Liang, Fanhong Xu, Aoxiang Li, Lina Wu, Jingye Zhu, Jianhua Qiu, Jin Lu, Lin Zhang, Xin Zhao, Xiaofei Song
  • Mutant-type uricase, PEG modified mutant-type uricase, and application thereof
    Patent number: 11021690
    Abstract: A mutant-type uricase, PEG modified mutant-type uricase, and application thereof. The mutant-type uricase has a cysteine residue introduced by recombination, the cysteine residue is located at an inactive region of the uricase, and one or more PEGs are coupled to the mutant-type uricase. The resulting PEGylated mutant-type uricase has characteristics of a half-life extension, product uniformity, and stable enzyme activity. Therefore, the present invention has a wide future application range.
    Type: Grant
    Filed: August 19, 2016
    Date of Patent: June 1, 2021
    Assignee: SHANGHAI INSTITUTE OF BIOLOGICAL PRODUCTS CO., LTD.
    Inventors: Yun Jiang, Linqiu Huang, Jueren Lou