Abstract: The present disclosure relates to a method and a system for determining a cell migration capacity. The method includes performing a scratching operation on cells by a cell scratching device to form at least one scratch and photographing and analyzing the at least one scratch by a cell image analysis device to determine a migration capacity of the cells.

Abstract: One or more embodiments of the present disclosure disclose a culture device. The culture device may include a chamber layer including at least one culture chamber for accommodating a culture; a sample introduction channel in flow communication with the at least one culture chamber, the sample introduction channel being configured to guide the culture into or out of the at least one culture chamber; and a culture fluid channel in flow communication with the at least one culture chamber, the culture fluid channel being configured to guide a culture fluid into or out of the at least one culture chamber.

Abstract: A system for acquiring multi-fluorescence images includes an excitation light source configured to irradiate an excitation beam onto a surface of a test sample, so that the test sample emits multi-fluorescence signals. The multi-fluorescence signals include at least two fluorescence signals. The system also includes an optical detection device configured to acquire the multi-fluorescence signals, an optical lens disposed between the optical detection device and the test sample, and a multi-band filter disposed between the optical detection device and the optical lens and/or between the test sample and the optical lens. The optical lens is configured to converge the multi-fluorescence signals emitted by the test sample to the optical detection device. The multi-band filter has at least two transmission intervals corresponding to at least two wavelength intervals of the at least two fluorescence signals.

Abstract: The present disclosure provides a counting chamber and an application thereof, and a method and a system for analyzing particles in a test sample. The method includes obtaining a full volume image of the test sample using an image acquisition device, wherein an imaging field of the full volume image is capable of reflecting an entire volume of the test sample in a sample container. The method further includes determining an analysis parameter of the particles in the test sample based on the full volume image, wherein the analysis parameter of the particles includes at least a count of the particles.

Abstract: Embodiments of the present disclosure may teach a counting assembly, a counting device, and applications thereof. The counting assembly may include a main body. The main body may be provided with a concave sample tank, a bottom end of a sample tank being plane. A cross-sectional area of the sample tank may gradually increase from the bottom end to a top end of the sample tank. By using the counting assembly, obtaining a count of particles or cells, etc. of the sample in the sample tank may be realized by imaging the sample for one or more times, which makes the process fast and efficient, as well as minimizing the counting error generated by an uneven distribution of the particles or cells and/or a limited sampling of the particles or cells, etc.

Abstract: The embodiments of the present disclosure provide a sample analysis device and a sample analysis system. The sample analysis device includes a base and one or more sample analysis units provided on the base. Each sample analysis unit includes a liquid storage chamber, an optical imaging chamber, a drainage chamber, and a sealing element. The liquid storage chamber is arranged on the base. The optical imaging chamber is arranged on the base, and a side of the optical imaging chamber is connected to the liquid storage chamber. The drainage chamber is arranged on the base. The drainage chamber is connected to the other side of the optical imaging chamber, and the drainage chamber is provided with an opening connecting with atmosphere. The sealing element removably seals the opening.

Abstract: The present disclosure provides a microscopic imaging system. The microimaging system includes a sample platform control structure and/or a platform mechanism for the microscopic imaging system. The sample platform control structure includes a base, an X platform, an X platform moving mechanism, a sample platform, a sample platform moving mechanism, a primary guide rail, and a secondary guide rail. The platform mechanism for the microscopic imaging system includes the sample platform control structure and a Y platform, a Y platform moving mechanism, a Z platform, a Z platform moving mechanism, and an imaging device.

Abstract: The present disclosure discloses a culture device and method. The culture device includes a substrate, wherein a surface of the substrate includes a plurality of culture regions. Each of the plurality of culture regions are configured to adhere a culture. An adhesion affinity of an interior of each of the plurality of culture regions is greater than an adhesion affinity of an exterior of each of the plurality of culture regions. The present disclosure further discloses a culture method for biological culture using the culture device.

Abstract: The embodiments of the present disclosure provide a reflection mechanism of a microscopic imaging device, a microscopic imaging device and a method thereof. The microscopic imaging device includes: a carrier assembly including a carrier table, the carrier table being configured to support a sample to be observe; an imaging assembly configured to obtain a microscopic image of the sample by photographing the sample; wherein the imaging assembly includes a camera unit and a lens unit, the camera unit at least includes a camera, and the lens unit at least includes a lens, and the camera and/or the carrier table is capable of adjusting an object-image distance by moving along an imaging optical path of the imaging assembly, and the lens is capable of adjusting an object distance and an image distance by moving along the imaging optical path.

Abstract: A method for laser distance measuring includes: emitting an incident ray ? having an incident angle ? to a reflective surface of a laser reflecting mirror (31), the incident ray ? being reflected by the laser reflecting mirror (31) to generate a first reflected ray ?, and the first reflected ray ? irradiating an object to be measured (1000); capturing a second reflected ray ? and generating a laser image on a laser imaging plane (3221), the second reflected ray ? being generated by the reflective surface of the laser reflecting mirror (31) reflecting a return ray ? generated after the first reflected ray ? irradiates a surface of the object to be measured; and determining, based on the laser image, a measurement distance A according to a geometrical trigonometry.

Abstract: The present disclosure provides an in vitro life culture system, comprising: a culture module used to cultivate a culture, the culture module including at least a culture chamber for holding a culture fluid; a culture fluid provision module used to provide the culture fluid to the culture module; and a fluid output module used to discharge the culture fluid from the culture chamber.

Abstract: The present disclosure disclose a microscopic device and a focusing method of the microscopic device, the microscopic device includes an object stage configured to carry a transparent carrier and drive the transparent carrier to translate along at least one direction, the transparent carrier includes at least two object positions; a microscopic objective located on a side of the object stage; a rangefinder located on a same side of the object stage as a microscopic objective and at a same height relative to the object stage, and the rangefinder is configured to measure a distance between a surface of each of the at least two object positions and the microscopic objective; a focusing module configured to adjust a position of the microscopic objective along a first direction based on the distance measured by the rangefinder, wherein the first direction is perpendicular to a carrying surface of the object stage.

Abstract: The embodiments of the present disclosure provide a method, a system, and an application for detecting at least one of a cell-killing efficacy or an immune activity. The method comprises: obtaining a plurality of microscopic images of a fixed area of a co-culture sample, wherein the co-culture sample is a cell sample obtained by co-culturing target cells and effector cells, the fixed area of the co-culture sample includes a plurality of objects, wherein the plurality of objects are a cell group including cells with different properties, each of the plurality of objects having an image-identifiable feature; performing an image overlapping synthesis analysis or an image fusion analysis for the plurality of microscopic images to obtain the cell properties of the plurality of objects and make statistics to cell parameters associated with the cell properties; and evaluating at least one of the cell-killing efficacy or the immune activity of the effector cells based on the cell parameters.

Abstract: A method for analysis of algae, comprising: receiving a microscopic image of algae by a cloud server (2501), the microscopic image including a scaling pattern for determining a magnification; determining the magnification by the cloud server based on the scaling pattern (2502); and analyzing the microscopic image by the cloud server based on the magnification to obtain an analysis result (2503).

Abstract: The present disclosure provides a perfusion system and a cell cultivation perfusion system, the perfusion system comprising: a pressure transfer component, the pressure transfer component including a belt and multiple pressure members disposed on the belt at intervals; a driving device, a driving connection being established between the driving device and the pressure transfer component; and at least one pipeline assembly, the at least one pipeline assembly including at least one pressable pipeline for fluid flow; wherein a press area is formed between the pressure transfer component and each of the at least one pressable pipeline, the multiple pressure members move with the belt, and at least a portion of the multiple pressure members press against the at least one pressable pipeline in the press area.

Abstract: A method for analysis of yeast includes: receiving a microscopic image of yeast by a cloud server (2901), the microscopic image including a scaling pattern for determining a magnification; determining the magnification by the cloud server based on the scaling pattern (2902); and analyzing, by the cloud server, the microscopic image based on the magnification to obtain an analysis result (2903).

Abstract: One or more embodiments of the present disclosure relate to a culture device, which comprises: an accommodation base, an accommodation chamber disposed on the accommodation base. The accommodation chamber includes a culture chamber for accommodating one or more cultures. The culture chamber includes a chamber bottom wall and a chamber side wall surrounding the chamber bottom wall. A culture solution channel is formed between an outer side of the chamber side wall and an inner wall of the accommodation chamber. At least part of the chamber side wall includes a membrane material, and a plane where the membrane material is located intersect with the chamber bottom wall.

Abstract: A particle detection device is provided. The particle detection device may include a substrate and at least one detection unit setting on the substrate.

Abstract: A method for analysis of algae, comprising: receiving a microscopic image of algae by a cloud server (2501), the microscopic image including a scaling pattern for determining a magnification; determining the magnification by the cloud server based on the scaling pattern (2502); and analyzing the microscopic image by the cloud server based on the magnification to obtain an analysis result (2503).

Abstract: A method for analysis of yeast includes: receiving a microscopic image of yeast by a cloud server (2901), the microscopic image including a scaling pattern for determining a magnification; determining the magnification by the cloud server based on the scaling pattern (2902); and analyzing, by the cloud server, the microscopic image based on the magnification to obtain an analysis result (2903).