Patents Assigned to SHANGHAI TARGETDRUG CO., LTD.
  • Amide compounds, their pharmaceutical compositions, their preparation method and their uses
    Patent number: 8410094
    Abstract: The present invention pertains to the field of pharmaceutical chemistry and discloses 8-(3-aminopropyl)-3-exo-8-azabicyclo[3.2.1]octane-3-amino amide compounds represented by formula I, the pharmaceutical compositions, the preparation method and the use thereof. Such compounds or pharmaceutically acceptable salts thereof can be used as an antagonist of CCR5 in preparing medicaments for treating diseases mediated by CCR5, particularly HIV infection, asthma, rheumatoid arthritis, autoimmune diseases and chronic obstructive pulmonary diseases (COPD).
    Type: Grant
    Filed: September 18, 2009
    Date of Patent: April 2, 2013
    Assignees: Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai Targetdrug Co., Ltd.
    Inventors: Yaqiu Long, Xing Fan, Dongzhi Feng, Li Chen, Renhai Chen
  • AMIDE COMPOUNDS, THEIR PHARMACEUTICAL COMPOSITIONS, THEIR PREPARATION METHOD AND THEIR USES
    Publication number: 20110251192
    Abstract: The present invention pertains to the field of pharmaceutical chemistry and discloses 8-(3-aminopropyl)-3-exo-8-azabicyclo[3.2.1]octane-3-amino amide compounds represented by formula I, the pharmaceutical compositions, the preparation method and the use thereof. Such compounds or pharmaceutically acceptable salts thereof can be used as an antagonist of CCR5 in preparing medicaments for treating diseases mediated by CCR5, particularly HIV infection, asthma, rheumatoid arthritis, autoimmune diseases and chronic obstructive pulmonary diseases (COPD).
    Type: Application
    Filed: September 18, 2009
    Publication date: October 13, 2011
    Applicants: SHANGHAI TARGETDRUG CO., LTD., SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
    Inventors: Yaqiu Long, Xing Fan, Dongzhi Feng, Li Chen, Renhai Chen