Abstract: An application of Anle138b in a drug for improving diet-induced insulin resistance is provided. Anle138b has obvious improvement effects on both preventing and treating insulin resistance, and can reduce the intake efficiency and the body weight. Besides, Anle138b can effectively improve diet-induced ectopic fat storage and adipose tissue hypertrophy, and the effect of Anle138b on improving insulin resistance is independent of the reduction of food intake.

Abstract: Disclosed is a method for analyzing a distribution of retinal lesions in a mouse model, including: scanning a mouse posterior polar fundus based on optical coherence tomography (OCT), and acquiring lesion images of the mouse posterior polar fundus; acquiring lesion distribution coordinates based on the lesion images of the mouse posterior polar fundus; constructing a coordinate map of a lesion distribution rule based on the lesion distribution coordinates; and acquiring lesion distribution in quadrants based on the coordinate map of the lesion distribution rule, and calculating and counting a number of lesions in each quadrant.

Abstract: Disclosed is a method for fabricating a wearable hydrogel glucose sensor, belonging to the technical field of biomedical sensing, including using polyacrylamide hydrogel as a basic material, preparing a hydrogel film by adding with phenylboronic acid group capable of recognizing glucose molecules, and carrying out grating writing on the hydrogel film in a femtosecond laser direct writing mode to obtain the wearable hydrogel glucose sensor. The hydrogel film combines with glucose and expands linearly, which makes the grating period and effective refractive index change. The quantitative measurement of glucose is realized by detecting the spatial position of diffraction band and the change of diffraction power intensity.

Abstract: Disclosed are a data analysis method and a data analysis system for retinal nerve fibrous layer. The method comprises the following steps: obtaining a peripapillary RNFL scanning image and a full-circumference RNFL thickness measurement data distribution image; obtaining a fundus scanning image, measuring a optic disc macular inclination angle; obtaining the upper and lower range of the RNFL scanning image, and measuring the upper and the lower RNFL thickness; obtaining an intersection position of an RNFL measuring ring and a blood vessel according to the canning image, and respectively correcting the upper and the lower RNFL thickness; performing a symmetry evaluation of the upper and the lower RNFL thickness according to the upper and the lower RNFL thickness correction value, and judging whether the RNFL data is abnormal. The system includes: image acquisition module, macular angle module, RNFL thickness module, RNFL thickness correction module and RNFL data evaluation module.

Abstract: A femoral neck measuring method includes: measuring an affected limb after a femoral stem prosthesis is installed through an optical localization probe, and calculating an actual length of the femoral neck needed by the affected limb according to an osteotomy surface of the affected limb determined after the femoral stem prosthesis is installed; determining a femoral ball prosthesis and a femoral neck prosthesis to be selected according to the calculated actual length of the femoral neck and a length of a femoral neck of a healthy limb measured before surgery; and measuring a length of the affected limb after the femoral ball prosthesis and the femoral neck prosthesis are implanted, and restraining a length difference between the healthy limb and the affected limb by adjusting a length of the femoral neck of the affected limb.

Abstract: The present invention relates to an integrated device for hair follicle extraction and implanting, comprising a body mechanism and a connecting mechanism, the body mechanism comprising a body supporting frame, a first motor, a transmission frame, a second motor, a clamping component, a transmission mechanism and a pushing needle, the connecting mechanism comprises a connecting head, a fixing head and a cutter head, wherein the first motor of the body mechanism controls the up and down movement of the cutter head through the cooperation of the transmission frame and the transmission mechanism, and the second motor controls the pushing needle by the rotary motion of the clamping unit, simultaneously controls the rotational movement of the cutter head through the transmission mechanism. Compared with the prior art, the invention realizes the integrated operation of hair follicle extracting and implanting, and makes the operation of hair follicle implanting more convenient.

Abstract: The present invention provides a method for purifying a recombinant target protein by using an autolytic protein Intein, comprising: recombinantly expressing a fusion protein in a host cell, wherein said fusion protein comprises a target protein domain, an autolytic Intein and one or multiple hydrophobic granule binding domains, and wherein said autolytic Intein is located between said target protein domain and said one or multiple hydrophobic granule binding domains; releasing said fusion protein from said host cell, adding hydrophobic granules and incubating; collecting the incubated hydrophobic granules, adding a lysis solution for allowing the autolytic Intein in said fusion protein to disrupt; and removing said hydrophobic granules, to obtain a solution containing said target proteins which are substantially purified. The present invention further provides a kit for performing such a method.

Abstract: The present invention is related to the use of hydroxyalkanoic acid derivatives as a fuel additive. In particular, the present invention provides the use of lower alkyl esters and/or salts of hydroxyalkanoic acid as biofuels and/or fuel additives. The present invention also provides a fuel composition including at least one fuel and lower alkyl esters and/or salts of hydroxyalkanoic acid.