Patents Assigned to Shenzhen Pharmacin Co., Ltd.
  • Pharmaceutical compositions of amorphous solid dispersions and methods of preparation thereof
    Patent number: 11471418
    Abstract: Provided are amorphous solid dispersions comprising an active pharmaceutical ingredient and pharmaceutical compositions comprising the amorphous solid dispersions. Also described herein are methods for preparing and using such compositions. In some embodiments, an amorphous solid dispersion comprises an active pharmaceutical ingredient such as palbociclib or neratinib, one or more acids, and a high-molecular weight material.
    Type: Grant
    Filed: November 13, 2020
    Date of Patent: October 18, 2022
    Assignee: Shenzhen Pharmacin Co., Ltd.
    Inventors: Zeren Wang, Shun Chen, Longwei Sun, Yanxin Zhao
  • Pharmaceutical formulation of palbociclib and a preparation method thereof
    Patent number: 11464779
    Abstract: The present invention belongs to the pharmaceutical field, and in particular, it relates to a pharmaceutical formulation of palbociclib and a preparation method thereof. The pharmaceutical formulation comprises palbociclib, an acidic auxiliary material, and optionally a hydrophilic high-molecular material, which has better solubility and in vitro dissolution property as compared with the conventional formulation and can be used for enhancing in vivo absorption and bioavailability of palbociclib.
    Type: Grant
    Filed: September 17, 2020
    Date of Patent: October 11, 2022
    Assignee: Shenzhen Pharmacin Co., Ltd.
    Inventors: Zeren Wang, Jun Xu, Long Qu
  • Preparation method therefor
    Patent number: 11083721
    Abstract: The present invention provides an oral pharmaceutical composition and a usage thereof, comprising a pharmaceutically acceptable acidic medicinal auxiliary material whose surface is modified and dabigatran etexilate or pharmaceutically acceptable salts or aquo-complexes thereof. The present invention further provides a surface modification method for a medicinal auxiliary material.
    Type: Grant
    Filed: December 26, 2019
    Date of Patent: August 10, 2021
    Assignee: Shenzhen Pharmacin Co., Ltd.
    Inventors: Zeren Wang, Yulan Zhao, Lijiang Wang, Xiao Zhang, Jun Xu, Shunqin Chen, Meili Sun, Guisheng Jiang
  • Pharmaceutical formulation of palbociclib and a preparation method thereof
    Patent number: 10894049
    Abstract: The present invention belongs to the pharmaceutical field, and in particular, it relates to a pharmaceutical formulation of palbociclib and a preparation method thereof. The pharmaceutical formulation comprises palbociclib, an acidic auxiliary material, and optionally a hydrophilic high-molecular material, which has better solubility and in vitro dissolution property as compared with the conventional formulation and can be used for enhancing in vivo absorption and bioavailability of palbociclib.
    Type: Grant
    Filed: August 28, 2019
    Date of Patent: January 19, 2021
    Assignee: Shenzhen Pharmacin Co., Ltd.
    Inventors: Zeren Wang, Jun Xu, Long Qu
  • Pharmaceutical composition and preparation method therefor
    Patent number: 10864204
    Abstract: The present invention provides an oral pharmaceutical composition and a usage thereof, comprising a pharmaceutically acceptable acidic medicinal auxiliary material whose surface is modified and dabigatran etexilate or pharmaceutically acceptable salts or aquo-complexes thereof. The present invention further provides a surface modification method for a medicinal auxiliary material.
    Type: Grant
    Filed: October 10, 2018
    Date of Patent: December 15, 2020
    Assignee: SHENZHEN PHARMACIN CO., LTD.
    Inventors: Zeren Wang, Yulan Zhao, Lijiang Wang, Xiao Zhang, Jun Xu, Shunqin Chen, Meili Sun, Guisheng Jiang
  • Pharmaceutical formulation of palbociclib and a preparation method thereof
    Patent number: 10813937
    Abstract: The present invention belongs to the pharmaceutical field, and in particular, it relates to a pharmaceutical formulation of palbociclib and a preparation method thereof. The pharmaceutical formulation comprises palbociclib, an acidic auxiliary material, and optionally a hydrophilic high-molecular material, which has better solubility and in vitro dissolution property as compared with the conventional formulation and can be used for enhancing in vivo absorption and bioavailability of palbociclib.
    Type: Grant
    Filed: August 28, 2019
    Date of Patent: October 27, 2020
    Assignee: Shenzhen Pharmacin Co., Ltd.
    Inventors: Zeren Wang, Jun Xu, Long Qu
  • Pharmaceutical formulation of palbociclib and a preparation method thereof
    Patent number: 10449195
    Abstract: The present invention belongs to the pharmaceutical field, and in particular, it relates to a pharmaceutical formulation of palbociclib and a preparation method thereof. The pharmaceutical formulation comprises palbociclib, an acidic auxiliary material, and optionally a hydrophilic high-molecular weight material, which has better solubility and in vitro dissolution property as compared with the conventional formulation and can be used for enhancing in vivo absorption and bioavailability of palbociclib.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: October 22, 2019
    Assignee: SHENZHEN PHARMACIN CO., LTD.
    Inventors: Zeren Wang, Jun Xu, Long Qu
  • Pharmaceutical composition and preparation method therefor
    Patent number: 10159664
    Abstract: The present invention provides an oral pharmaceutical composition and a usage thereof, comprising a pharmaceutically acceptable acidic medicinal auxiliary material whose surface is modified and dabigatran etexilate or pharmaceutically acceptable salts or aquo-complexes thereof. The present invention further provides a surface modification method for a medicinal auxiliary material.
    Type: Grant
    Filed: June 28, 2017
    Date of Patent: December 25, 2018
    Assignee: Shenzhen Pharmacin Co., Ltd.
    Inventors: Zeren Wang, Yulan Zhao, Lijiang Wang, Xiao Zhang, Jun Xu, Shunqin Chen, Meili Sun, Guisheng Jiang