Abstract: The disclosure provides an endoscope locking method in which a locking condition is set based on change in coordinates of a manipulation portion. When a sampled X coordinate and Y coordinate of the manipulation portion meet a set change in coordinates of the manipulation portion, a locking signal is sent out, and thus an endoscope is locked. The method can achieve one-hand manipulation, and automatically achieves the locking of the endoscope according to the change in coordinates of the manipulation portion.