Patents Assigned to SHILPA MEDICARE LIMITED
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Patent number: 11857680Abstract: The present invention relates to a pharmaceutical liposomal composition comprising of about 0.8% w/w to about 1% w/w of docetaxel, about 30% w/w to about 38% w/w of Soya Phosphatidyl Choline, about 0.2% w/w to about 0.8% w/w of Sodium Cholesteryl Sulfate, about 61% w/w to about 68% w/w of Sucrose and a pH adjusting agent, wherein the pH of liposomal composition is less than 3.5 and the process for preparation thereof.Type: GrantFiled: October 19, 2020Date of Patent: January 2, 2024Assignee: SHILPA MEDICARE LIMITEDInventors: Kiran K Jadhav, Prashanth S, Shivakumar Pradeep, Sreenivasa Reddy
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Patent number: 11857556Abstract: The present invention relates to a composition for topical application for preventing hair loss, androgenic alopecia (AA) and stimulating hair growth having dutasteride. The composition for topical application for preventing hair loss and stimulating hair growth according to the present invention provides equal or superior hair loss prevention and hair growth stimulating effects while using much smaller dosage than the conventional compositions (oral dosage form) which use finasteride and dutasteride.Type: GrantFiled: April 26, 2021Date of Patent: January 2, 2024Assignee: SHILPA MEDICARE LIMITEDInventors: Rajendar Medishetty, Agadihiremath Thippeswamy, Sreenivasa Reddy, Shivakumar Pradeep
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Patent number: 10993934Abstract: The present invention relates to a composition for topical application for preventing hair loss, androgenic alopecia (AA) and stimulating hair growth having dutasteride. The composition for topical application for preventing hair loss and stimulating hair growth according to the present invention provides equal or superior hair loss prevention and hair growth stimulating effects while using much smaller dosage than the conventional compositions (oral dosage form) which use finasteride and dutasteride.Type: GrantFiled: June 18, 2018Date of Patent: May 4, 2021Assignee: SHILPA MEDICARE LIMITEDInventors: Rajendar Medishetty, Agadihiremath Thippeswamy, Sreenivasa Reddy, Shivakumar Pradeep
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Patent number: 10842771Abstract: The present invention relates to a pharmaceutical liposomal composition comprising of about 0.8% w/w to about 1% w/w of docetaxel, about 30% w/w to about 38% w/w of Soya Phosphatidyl Choline, about 0.2% w/w to about 0.8% w/w of Sodium Cholesteryl Sulfate, about 61% w/w to about 68% w/w of Sucrose and a pH adjusting agent, wherein the pH of liposomal composition is less than 3.5 and the process for preparation thereof.Type: GrantFiled: November 26, 2018Date of Patent: November 24, 2020Assignee: SHILPA MEDICARE LIMITEDInventors: Kiran K Jadhav, Prashanth S, Shivakumar Pradeep, Sreenivasa Reddy
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Publication number: 20200339588Abstract: The present invention relates to novel crystalline and amorphous polymorphic forms of Ribociclib(1) mono succinate. (I) Said crystalline forms may be useful in the improved preparation of oral dosage forms for the treatment of cancer.Type: ApplicationFiled: December 12, 2018Publication date: October 29, 2020Applicant: SHILPA MEDICARE LIMITEDInventors: SRIRAM RAMPALLI, LAV KUMAR UPALLA, SURYANARAYAN CHERUKUVADA, CHANTI BABU PATNEEDI, GOPALA KRISHNA DASARI, VIJAYA MURALI MOHAN RAO SESHAGIRI
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Patent number: 10722498Abstract: The present invention provides a stable, ophthalmic aqueous composition for topical administration comprising acetazolamide and an aqueous liquid capable of forming a pharmaceutically acceptable gel in situ when applied topically to a patient, said composition has the pH of less than 4.5.Type: GrantFiled: January 22, 2018Date of Patent: July 28, 2020Assignee: SHILPA MEDICARE LIMITEDInventors: Andanayya Saraganachari, Abhilash Narayanaswamy, Sreenivasa Reddy, Shivakumar Pradeep
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Patent number: 10702578Abstract: The present invention relates to the ophthalmic composition comprising from about 0.03% to about 2% by weight of cyclosporine, from about 0.05% to about 5% by weight of tamarind seed polysaccharide and a pharmaceutically acceptable carrier. Further the invention relates to the process for preparation of ophthalmic compositions and its use for the treatment of dry eye.Type: GrantFiled: August 1, 2018Date of Patent: July 7, 2020Assignee: SHILPA MEDICARE LIMITEDInventors: Vara Prasad Rangabhatla Gunneswara Subramanya, Sandeep Kalepu, Ratna Phani Ayalasomayajula
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Patent number: 10682326Abstract: The present invention relates to a stable, non-aqueous liquid, formulation consisting essentially of melphalan, or a pharmaceutical acceptable salt thereof; and one or more solvents selected from group consisting of dimethyl acetamide, polyethylene glycol, ethanol, propylene glycol, dimethyl sulfoxide, N-methylpyrrolidone and glycerol; wherein said formulation is free of antioxidants, organic acid and added chloride ions; and the process for preparation thereof.Type: GrantFiled: July 17, 2019Date of Patent: June 16, 2020Assignee: SHILPA MEDICARE LIMITEDInventors: Shivakumar Pradeep, Krishnamurthy Toppaladoddi, Rizwan Ahmed, Guptha Chinni Guru Deva, Nagaraju Dasari
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Patent number: 10583133Abstract: The present invention relates to a pharmaceutical composition comprising lenvatinib mesylate and a stabilizer in an amount of about 10% to about 20% based on the total weight of the composition, wherein the stabilizer is selected from the group consisting of calcium hydroxide and potassium hydroxide; and its process for preparation thereof.Type: GrantFiled: March 1, 2019Date of Patent: March 10, 2020Assignee: SHILPA MEDICARE LIMITEDInventors: Nijaguni Revansiddayya Rudraswamy Math, Sreenivas Reddy, Ravi Vamsi Peri, Krishnamurthy Toppaladoddi, Shivakumar Pradeep
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Patent number: 10583216Abstract: The present invention relates to hemostatic scaffold compositions and the method of preparation thereof. In present invention, hemostatic scaffold compositions for wound care and dental care, uses chitosan and tranexamic acid.Type: GrantFiled: December 12, 2017Date of Patent: March 10, 2020Assignee: SHILPA MEDICARE LIMITEDInventors: Gunneswara Subramanya Vara Prasad Rangabhatla, Sai Laxmi Aparna Rangabhatla, Ratna Phani Ayalasomayajula
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Patent number: 10561583Abstract: The present invention relates to dental cement composition that is more biocompatible and stimulates quicker healing of the damaged dental tissues. Specifically, the invention relates to dental cement composition comprising a combination of dental repair compounds consisting of nanoparticles of Tri-calcium Silicate (Ca3SiO5), Di-calcium Silicate (Ca2SiO4), Calcium Titanate (CaTiO3) and Hydroxyapatite (Ca10(PO4)6(OH)2).Type: GrantFiled: August 9, 2017Date of Patent: February 18, 2020Assignee: SHILPA MEDICARE LIMITEDInventors: Gunneswara Subramanya Vara Prasad Rangabhatla, Shrisha Belaldavara, Ratna Phani Ayalasomayajula
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Patent number: 10435409Abstract: The present invention relates to a process for the preparation of 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one or Ibrutinib of Formula (I). The present invention further relates to a process for the preparation highly pure 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one or Ibrutinib(I).Type: GrantFiled: February 2, 2017Date of Patent: October 8, 2019Assignee: SHILPA MEDICARE LIMITEDInventors: Sriram Rampalli, Lav Kumar Upalla, Chanti Babu Patneedi, Gopala Krishna Dasari, Akshay Kant Chaturvedi
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Patent number: 10414764Abstract: The present invention relates to a process for the preparation substantially pure propane-1-sulfonicacid-{3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide or Vemurafenib of Formula (I).Type: GrantFiled: November 19, 2015Date of Patent: September 17, 2019Assignee: SHILPA MEDICARE LIMITEDInventors: Purohit Prashant, Nagnnath Kokare, Veera Reddy Yenireddy, Chaturvedi Akshay Kant
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Patent number: 10226450Abstract: The present invention relates to Film Compositions of Ondansetron or its pharmaceutically acceptable salt thereof, which dosage forms are useful for the treatment of various medical conditions.Type: GrantFiled: November 7, 2014Date of Patent: March 12, 2019Assignee: SHILPA MEDICARE LIMITEDInventors: Navneet Mundada, Ritesh Vinod Birla, Badrinath Allampalli, Akshay Kant Chaturvedi
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Publication number: 20190040069Abstract: The present invention relates to a process for the preparation of 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one or Ibrutinib of Formula (I).Type: ApplicationFiled: February 2, 2017Publication date: February 7, 2019Applicant: SHILPA MEDICARE LIMITEDInventors: SRIRAM RAMPALLI, LAV KUMAR UPALLA, CHANTI BABU PATNEEDI, GOPALA KRISHNA DASARI, AKSHAY KANT CHATURVEDI
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Publication number: 20180334457Abstract: The present invention relates to a process for the preparation substantially pure propane-1-sulfonicacid-{3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide or Vemurafenib of Formula (I).Type: ApplicationFiled: May 28, 2018Publication date: November 22, 2018Applicant: SHILPA MEDICARE LIMITEDInventors: PUROHIT PRASHANT, NAGNNATH KOKARE, VEERA REDDY YENIREDDY, CHATURVEDI AKSHAY KANT
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Publication number: 20170320872Abstract: The present invention relates to a process for the preparation substantially pure propane-1-sulfonicacid-{3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide or Vemurafenib of Formula (I).Type: ApplicationFiled: November 19, 2015Publication date: November 9, 2017Applicant: SHILPA MEDICARE LIMITEDInventors: PUROHIT PRASHANT, NAGNNATH KOKARE, VEERA REDDY YENIREDDY, CHATURVEDI AKSHAY KANT
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Patent number: 9789113Abstract: The present application provides pharmaceutical compositions derived from pemetrexed dipotassium Nonahydrate and its process thereof. The present application also provides a method of treating cancer by administering intravenously the reconstituted lyophilized compositions into a patient in need thereof.Type: GrantFiled: June 23, 2015Date of Patent: October 17, 2017Assignee: SHILPA MEDICARE LIMITEDInventors: Pradeep Shivakumar, Akshay Kant Chaturvedi
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Patent number: 9790185Abstract: The present invention relates to a process for the preparation of 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide or Regorafenib (I). The present invention further relates to a process for the purification of 4-[4-({[4-chloro-3-(trifluoromethyl) phenyl] carbamoyl} amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide or Regorafenib (I) to provide highly pure material. The present invention further relates to a process for the preparation stable crystalline material of 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methyl pyridine-2-carboxamide or Regorafenib (I) useful in the preparation of pharmaceutical compositions for the treatment of cancer.Type: GrantFiled: July 6, 2015Date of Patent: October 17, 2017Assignee: SHILPA MEDICARE LIMITEDInventors: Sriram Rampalli, Lav Kumar Upalla, Krishna Kumar Ramachandrula, Prashant Purohit, Chaturvedi Akshay Kant
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Patent number: 9765108Abstract: The present invention relates to polymorphic forms of 5-Azacytidine and the process for preparation thereof. The present invention further relates to Crystalline 5-azacytidine 5 designated as Form-SA-1 characterized by an X-ray powder diffraction pattern having at least four characteristic diffraction angle peaks at about 12.00, 12.60, 13.90, 15.15 and 31.40±0.20 2?°, which is useful as active pharmaceutical ingredient in pharmaceutical compositions for the treatment of myelodysplastic syndrome.Type: GrantFiled: November 8, 2013Date of Patent: September 19, 2017Assignee: SHILPA MEDICARE LIMITEDInventors: Pradeep Shivakumar, Nagaraju Dasari, Ravi Kishore, Rizwan Ahmed, Akshaykant Chaturvedi