Abstract: A separation channel on which a liquid delivery pump, a separation column, and a detector are provided, the liquid delivering pump being for feeding a mobile phase, the separation column being for separating a component in a sample, and the detector being for detecting peaks of components separated from each other by the separation column, a plurality of liquid handlers each including an injecting part and a collecting part, wherein when one of the plurality of liquid handlers is introduced into the separation channel, the injecting part of the one of the plurality of liquid handlers functions as an injector that executes injection operation of a sample into a mobile phase flowing through the analysis channel upstream of the separation column in the analysis channel and the collecting part of the one the plurality of liquid handlers functions as a fraction collector that executes collection operation of peaks of components separated from each other in the separation column, a selector for selectively switchin

Abstract: A driving part of an analysis device includes a cylindrical part on one surface of which a moving mirror is fixed, and a VCM connected at another surface of the cylindrical part and reciprocating the cylindrical part. The VCM includes: a yoke in a cylindrical shape; magnets provided at two ends of the yoke; a fixing part which is in a cylindrical shape enclosing the yoke and fixes, at a bottom surface, the yoke provided with the magnets; a lid part provided with windows and covering an opening surface of the fixing part; a moving part which is arranged between the yoke and the fixing part and on which a coil in a cylindrical shape is fixed; and support parts each including one end fixed to the moving part and another end connected at the another surface of the cylindrical part through the window.

Abstract: An imaging analysis device according to the present invention includes: an analysis execution unit (1) configured to perform analysis by a predetermined analysis method for each of a plurality of measurement points set in a measurement area on a sample and collect imaging data; a reference image acquiring unit (2) configured to acquire a reference image for the measurement area; a regression analysis executer (36) configured to, with respect to the imaging data and the reference image obtained for the same sample, perform predetermined regression analysis calculation with the imaging data as an explanatory variable and data constituting the reference image as a target variable and acquire a regression model; and a predicted image creator (37) configured to apply, to the regression model, imaging data obtained by the analysis execution unit using a sample different from the sample used in the regression analysis executer, and create a predicted image based on a pseudo regression analysis result.

Abstract: A light source emits excitation light to discharge gas that flows through a dielectric tube. A ground electrode unit includes a first ground electrode and a second ground electrode arranged at a distance from each other in an axial direction of the dielectric tube. A high-voltage electrode is provided between the first ground electrode and the second ground electrode. A first distance between the first ground electrode and the high-voltage electrode is shorter than a second distance between the second ground electrode and the high-voltage electrode. A cover is provided on an outer wall of the dielectric tube at a position between the first ground electrode and the high-voltage electrode. The light source is arranged to emit excitation light such that an optical axis thereof is directed toward a position where the cover is not provided on the outer wall of the dielectric tube.

Abstract: A phase image is formed by calculation from a hologram image of a cell, and segmentation is performed for each pixel for the phase image using a fully convolution neural network to identify an undifferentiated cell region, a deviated cell region, a foreign substance region, and the like. When learning, when a learning image included in a mini-batch is read, the image is randomly inverted vertically or horizontally and then is rotated by a random angle. A part that has been lost within the frame by the pre-rotation image is compensated for by a mirror-image inversion with an edge of a post-rotation image as an axis thereof. Learning of a fully convolution neural network is performed using the generated learning image. The same processing is repeated for all mini-batches, and the learning is repeated by a predetermined number of times while shuffling the training data allocated to the mini-batch. The precision of the learning model is thus improved.

Abstract: This X-ray imaging apparatus includes an X-ray source, an X-ray detector, an arm, an arm driving mechanism, an X-ray detector moving mechanism, a bed, and a control unit. The control unit performs control of a position adjustment operation for adjusting a position of the X-ray detector such that a distance from a surface of a subject model serving as a model of a surface shape of the subject to the X-ray detector becomes a predetermined distance by moving the X-ray detector toward or away from the surface of the subject model.

Abstract: A displacement measurement device 10 is provided with: a laser light source 11 for emitting laser light to a measurement area R of a measurement target object S; a focusing optical system (the beam splitter 151, the first reflecting mirror 1521, the condenser lens 155) having a front focal point in the measurement area R and a rear focal point on a predetermined imaging surface (the detection surface 1561); a non-focusing optical system (the beam splitter 151, the diffuser 153, the second reflecting mirror 1522, and the condenser lens 155) in which light from a measurement area R of a correspondence point in the measurement area corresponding to each point of the imaging surface with respect to the focusing optical system is incident on the point of the imaging surface; and a photodetector (image sensor 156) configured to detect light intensity on the imaging surface for each point.

Abstract: A liquid delivery pump includes a primary plunger pump, a secondary plunger pump fluidly connected in series downstream of the primary plunger pump, and a pressure sensor that detects a system pressure. The liquid delivery pump further includes a liquid delivery control part configured to execute first constant pressure control in a first constant pressure control term and to execute second constant pressure control in a second constant pressure control term. The first constant pressure control term is a term, which is in a liquid delivery cycle consisting of the primary discharge process and the secondary discharge process, in which the primary discharge process is executed, the second constant pressure control term is a part of a term in which the secondary discharge process is executed, and the second constant pressure control term is including a term that is continuous after the first constant pressure control term.

Abstract: Provided is a chromatography system including a usage information storage device, a column usage information holding part, and a usage information managing part. The usage information storage device is provided corresponding to the analytical column incorporated in the chromatography system and is configured to keep usage information for each corresponding analytical column. The column usage information holding part is provided separately from the analytical column and is configured to keep usage information for each of the analytical columns which may be incorporated in the chromatography system. The usage information managing part is configured to update, at a timing when an analysis process of separating a sample injected into the analysis channel using the analytical column is executed, the usage information kept by the usage information storage device and the usage information kept by the column usage information holding part in association with the analytical column to latest usage information.

Abstract: For a low-cost, high-accuracy tuning of the voltages applied to electrodes in a mass spectrometer, a chromatograph mass spectrometer (1) includes: a medium supplier (11) which supplies a medium as a mobile phase or carrier gas; a passage (15) which introduces, into the mass spectrometer, the medium supplied from the medium supplier; an ionizer (211) which ionizes the medium together with a substance coming from a member forming the passage into the medium; a measurement executer (25, 26, 43) which performs a mass separation and a measurement of a specific ion, using multiple measurement conditions which differ from each other in the value of voltage applied to at least one electrode included in one or more electrodes in the mass spectrometer; and a voltage value determiner (44) which determines the value of voltage applied to each electrode so that the intensity of the ion satisfies a predetermined criterion.

Abstract: An ICP-MS includes a control device, a collision cell and a first electrode that are provided on an optical axis of plasma, and a second electrode, a mass separation device, and a detector that are provided on a detection axis. The control device sets, as an axis-shifting voltage to be applied to each electrode of the first electrode and the second electrode in a gas-present mode, the voltage obtained by adding an offset determined according to a mass-to-charge ratio of a target ion to an initial voltage in a gasless mode.

Abstract: A micro-Raman device includes a first laser light source, a second laser light source, a first holder, a second holder, a first ND filter, and a second ND filter. The first laser light source and the second laser light source generate first laser light of a first wavelength and second laser light of a second wavelength, respectively. The second wavelength is different from the first wavelength. The first laser light and the second laser light proceed in a second direction orthogonal to a first direction while being separated from each other in the first direction. The first holder and the second holder are arranged overlapping each other in the second direction.

Abstract: Provided is a mass spectrometer including a vacuum chamber containing a cell used for causing ions originating from a sample to come in contact with a predetermined gas supplied from a gas supplier (20), which includes a three-way valve (204) configured to selectively send the gas into either a first passage (22) for sending the predetermined gas to the cell or a second passage (23) for discharging the gas into vacuum state. The mass spectrometer also includes a controller configured to control the three-way valve so as to send the gas into the second passage during an analysis period in which ions are not caused to come in contact with the gas within the cell and/or during a non-analyzing period, as well as to send the gas into the first passage during an analysis period in which ions are caused to come in contact with the gas within the cell.

Abstract: The present disclosure provides a test method for assessing the possibility of infection of residents without performing periodic PCR tests of residents of a facility in question. One embodiment is an infectious disease test method that includes a sampling step for collecting a sample from sewage during a sampling period in a route from where sewage is discharged from a facility until flowing into a public sewage pipe, an analysis step for analyzing the sample to obtain information relating to the existence of an infectious disease pathogen in the sample, and a notification step for notifying the facility of the information together with the sampling period.

Abstract: A method for preparing a sample comprising a glycan includes: performing a lactonization reaction in which at least a part of sialic acids included in the glycan is lactonized; and performing an amidation reaction in which lactones of lactonized sialic acids are amidated through addition of an amidation reaction solution to the sample, the amidation reaction solution comprising at least one selected from the group consisting of ammonia, an amine, and a salt thereof that is reacted with the lactonized sialic acids.

Abstract: A surface analyzer is provided with a measuring unit, a scatter diagram generation unit, a cluster analysis unit, and a cluster region detection unit. The measuring unit acquires a signal reflecting a quantity of each of a plurality of components or elements that are analysis targets at a plurality of positions on a sample. The scatter diagram generation unit generates a scatter diagram based on a measurement result by the measuring unit. The cluster analysis unit performs the clustering of points in the scatter diagram. The cluster region detection unit acquires, based on clustering information given to each point in the scatter diagram by the cluster analysis unit, for each cluster, cluster region boundary information on a polygon having a predetermined number or less of vertices.

Abstract: A peak analyzing method for separating overlapping peaks observed in a second signal waveform representing a relationship between a second parameter and a signal intensity into a plurality of individual peaks originating from different factors based on signal patterns observed in a dimension of a first parameter, the method including at least: performing singular value decomposition on an input matrix expressing three-dimensional data to be processed; estimating characteristic orientations within a space spanned by a plurality of basis vectors by performing a geometric analysis on a trajectory defined by a plurality of weighting vectors in an SVD projection space whose number of dimensions is equal to a lowered rank given by a singular value decomposition process; and deconvoluting signal waveforms in a first matrix of a dimension of the first parameter by a transformation matrix.

Abstract: A quality control standard for peptide (including protein) measurement, and a quality control for peptide (including proteins) measurement are provided. A QC standard sample for measurement of a target peptide, the QC standard sample comprising: a blood sample comprising a peptide, and a peptide labeled with a stable isotope that is spiked into said blood sample. The target peptide to be measured includes, for example, at least one selected from the group consisting of A?1-42 (SEQ ID NO.: 9), A?1-38 (SEQ ID NO.: 11), A?1-40 (SEQ ID NO.: 7), and APP669-711 (SEQ ID NO.: 10). The peptide labeled with a stable isotope that is spiked into the blood sample includes, for example, at least one selected from the group consisting of SIL-A?1-42, SIL-A?1-38, SIL-A?1-40, and SIL-APP669-711.

Abstract: A flow rate switching mechanism including: a first section including: a first housing with a passage internally bored through, the passage having a narrowed portion at a distance from one end of the passage, and the narrowed portion having a smaller cross-sectional area than the cross-sectional area of the passage at the one end; a capillary having an internal passage having a smaller cross-sectional area than the cross-sectional area of the narrowed portion; and a hermetic support member supporting the capillary and to provide a seal; a second section having a second housing identical in shape to the first housing, without having the capillary and the hermetic support member; and a three-way valve being alternatively switchable between a first state in which the outlet end is connected to the first inlet end and a second state in which the outlet end is connected to the second inlet end.

Abstract: A mass spectrometer according to one aspect of the present invention includes an ion source (31), a mass separator (32), and a detector (33), the mass spectrometer further including: a parameter optimization unit (531, 532, 533) configured to optimize a parameter value using a Bayesian optimization method based on a result obtained by making measurements while changing values of device parameters including a plurality of parameters that affects ionization efficiency in the ion source (31), a display processor (536) configured to display a sensitivity model which is a posterior distribution indicating a relationship between a plurality of parameters in all or some of the device parameters and signal strength estimated during the optimization of the device parameters, expressing as a graph like a heat map or an array of a plurality of the graphs on a display unit (7), and to sequentially update the sensitivity model, and a file creation unit (535) configured to a user to designate a position on the displayed gr