Abstract: The present invention is to provide assemblies with polygon shaped panel frames, separators and parts for light weight construction that is versatile, rigid, flexible and structurally stable. The assemblies with polygon shaped panel frames, separators and parts for constructing a complete building structure eliminates the need for conventional framing using unitized polygon shaped panel frames with alignment pieces, separators and fastener parts connected together. The assemblies with polygon shaped panel frames, separators and parts comprises of panel frames which are different geometric shapes or polygon parts, including but not limited to circles, ovals, triangles, trapezoids, rectangles, squares, pentagons, hexagons, etc. Panel frames can be hollowed or solid and can be fabricated as pieces of and in itself. Panel frames can be composed of many types of materials including but not limited to wood, metal, polymers, composites, plastics, etc.