Abstract: The invention relates to (hetero)arylsulfonylamino based peptidomimetics of formula (I), wherein R1, R2, R3, A, B, D, Q, k and n are defined as disclosed, or a pharmaceutically acceptable salt or ester thereof. Compounds of formula (I) possess high affinity and selectivity for the somatostatin receptor subtypes SSTR1 and/or SSTR4 and can be used for the treatment or diagnosis of diseases or conditions wherein an interaction with SSTR1 and/or SSTR4 is indicated to be useful.
Type:
Grant
Filed:
October 5, 2004
Date of Patent:
June 22, 2010
Assignee:
Siegfried Wurster
Inventors:
Jussi Tomperi, Paivi Hautamaki, Harri Salo, Mia Engstrom, Andrei Tauber, Anna-Marja Hoffren, Siegfried Wurster
Abstract: The invention relates to 1-naphthalenesulfonylamino based peptidomimetics of formula (I), wherein B, R1 and R2 are as defined in the claims, and pharmaceutically acceptable salts thereof. Compounds of formula (I) possess high affinity and selectivity for the somatostatin receptor subtype SSTR4 or the somatostatin receptor subfamily SSTR1/SSTR4.
Type:
Application
Filed:
October 5, 2004
Publication date:
June 7, 2007
Applicant:
SIEGFRIED WURSTER
Inventors:
Jussi Tomperi, Mia Engstrom, Siegfried Wurster