Patents Assigned to Sigma-Tsu Industrie Farmaceutiche Riunite S.p.A.
  • Peptido-mimetic compounds containing RGD sequence useful as integrin inhibitors
    Patent number: 6437094
    Abstract: The present invention discloses compounds of formula (I) wherein n is the number 0, 1 or 2. There are also disclosed processes for the preparation of the compounds, together with methods for treating pathologies related to an altered &agr;v&bgr;3 integrin-mediated cell attachment, in particular wherein the inhibition of angiogenesis is desired, for example in tumors, also associated with metastasis.
    Type: Grant
    Filed: January 5, 2001
    Date of Patent: August 20, 2002
    Assignee: Sigma-Tsu Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Carlo Scolastico, Giuseppe Giannini