Patents Assigned to SINEW PHARMA INC.
  • Publication number: 20220265587
    Abstract: The present invention relates to compounds effective in treating hepatotoxicity and fatty liver diseases and uses thereof. The present compound is represented by Formula (II), which has the formula: R1—O—X—(CH2)m—X—O—R2, wherein: each X is —C(?O)—; R1 is a C1-C18 alkyl polyol; R2 is a saccharide group of formula (G)p; G is a monosaccharide residue, where (i) at least one of the —OH groups in (G)p is substituted by a halogen atom, and (ii) the saccharide group of formula (G)p is linked to —O— through a —CH2 group; p is 1 or 2; and m is 1, 2, 3, 4, 5, 6, 7, 8, 9 or 10.
    Type: Application
    Filed: March 3, 2022
    Publication date: August 25, 2022
    Applicant: SINEW PHARMA INC.
    Inventors: Oliver Yoa-Pu HU, Tung-Yuan SHIH, Cheng-Huei HSIONG, Hsin-Tien HO
  • Patent number: 11285123
    Abstract: The present invention relates to compounds effective in treating hepatotoxicity and fatty liver diseases and uses thereof. The present compound is represented by Formula (II), which has the formula: R1—O—X—(CH2)m—X—O—R2, wherein: each X is —C(?O)—; R1 is a C1-C18 alkyl polyol: R2 is a saccharide group of formula (G)p; G is a monosaccharide residue, where (i) at least one of the —OH groups in (G)p is substituted by a halogen atom, and (ii) the saccharide group of formula (G)p is linked to —O— through a —CH2 group; p is 1 or 2; and m is 1, 2, 3, 4, 5, 6, 7, 8, 9 or 10.
    Type: Grant
    Filed: September 17, 2019
    Date of Patent: March 29, 2022
    Assignee: SINEW PHARMA INC.
    Inventors: Oliver Yoa-Pu Hu, Tung-Yuan Shih, Cheng-Huei Hsiong, Hsin-Tien Ho
  • Patent number: 10925854
    Abstract: The present invention relates to methods and compositions for preventing or treating fatty liver, protecting liver function or ameliorating liver diseases caused by fatty liver or other associated disorders.
    Type: Grant
    Filed: March 31, 2016
    Date of Patent: February 23, 2021
    Assignee: SINEW PHARMA INC.
    Inventors: Oliver Yoa-Pu Hu, Hsin-Tien Ho, Yung-En Wu, Hsi-Hui Tang
  • Publication number: 20210008101
    Abstract: The present invention relates to methods and compositions for preventing, reducing or eradicating toxicity caused by acetaminophen (APAP). Specifically, the toxicity is nephrotoxicity and/or hepatotoxicity.
    Type: Application
    Filed: February 14, 2019
    Publication date: January 14, 2021
    Applicant: SINEW PHARMA INC.
    Inventors: Oliver Yoa-Pu HU, Tung-Yuan SHIH, Cheng-Huei HSIONG, Hsin-Tien HO, Kai-Min CHU
  • Publication number: 20200009097
    Abstract: The present invention relates to compounds effective in treating hepatotoxicity and fatty liver diseases and uses thereof. The present compound is represented by Formula (II), which has the formula: R1—O—X—(CH2)m—X—O—R2, wherein: each X is —C(?O)—; R1 is a C1-C18 alkyl polyol: R2 is a saccharide group of formula (G)p; G is a monosaccharide residue, where (i) at least one of the —OH groups in (G)p is substituted by a halogen atom, and (ii) the saccharide group of formula (G)p is linked to —O— through a —CH2 group; p is 1 or 2; and m is 1, 2, 3, 4, 5, 6, 7, 8, 9 or 10.
    Type: Application
    Filed: September 17, 2019
    Publication date: January 9, 2020
    Applicant: SINEW PHARMA INC.
    Inventors: Oliver Yoa-Pu HU, Tung-Yuan SHIH, Cheng-Huei HSIONG, Hsin-Tien HO
  • Patent number: 10456371
    Abstract: The present invention relates to compounds effective in treating hepatotoxicity and fatty liver diseases and uses thereof. The present compound is represented by Formula (II), which has the formula: R1—O—X—(CH2)m—X—O—R2, wherein: each X is —C(?O)—; R1 is a C1-C18 alkyl polyol; R2 is a saccharide group of formula (G)p; G is a monosaccharide residue, where (i) at least one of the —OH groups in (G)p is substituted by a halogen atom, and (ii) the saccharide group of formula (G)p is linked to —O— through a CH2 group; p is 1 or 2; and m is 1, 2, 3, 4, 5, 6, 7, 8, 9 or 10.
    Type: Grant
    Filed: September 26, 2016
    Date of Patent: October 29, 2019
    Assignee: SINEW PHARMA INC.
    Inventors: Oliver Yoa-Pu Hu, Tung-Yuan Shih, Cheng-Huei Hsiong, Hsin-Tien Ho
  • Publication number: 20180256526
    Abstract: The present invention relates to compounds effective in treating hepatotoxicity and fatty liver diseases and uses thereof.
    Type: Application
    Filed: September 26, 2016
    Publication date: September 13, 2018
    Applicant: SINEW PHARMA INC.
    Inventors: Oliver Yoa-Pu HU, Tung-Yuan SHIH, Cheng-Huei HSIONG, Hsin-Tien HO
  • Publication number: 20180117003
    Abstract: The present invention relates to methods and compositions for preventing or treating fatty liver, protecting liver function or ameliorating liver diseases caused by fatty liver or other associated disorders.
    Type: Application
    Filed: March 31, 2016
    Publication date: May 3, 2018
    Applicant: SINEW PHARMA INC.
    Inventors: Oliver Yoa-Pu HU, Hsin-Tien HO, Yung-En WU, Hsi-Hui TANG