Abstract: A Pharmaceutical formulation comprises a biologically active material such as insulin, erythropoietin, calcitonin and growth hormone, and, associated with it, a phospholipid for forming a material which participates in the alpha-glycerol or other pathways for the formation of lecithins which are found in the intestinal epithelial cell. Biologically active protein orally administered in such a formulation are bioavailable and bioactive.
Type:
Grant
Filed:
August 15, 1994
Date of Patent:
September 9, 1997
Assignee:
Skua Investments Limited
Inventors:
Young W. Cho, Michael John Flynn, Thomas Smith Shepherd