Patents Assigned to Sky High, LLC
  • Publication number: 20080076736
    Abstract: The invention provides anti-apoptotic compositions containing lysophosphatidic acids and methods for making and using the compositions. Such compositions may also contain LPA potentiating agents, including proteins, lipid membrane structures and polymers such as polyethylene glycols. The compositions can additionally contain other pharmaceutically effective agents such as drugs, antibiotics, wound healing agents and antioxidants.
    Type: Application
    Filed: August 6, 2007
    Publication date: March 27, 2008
    Applicant: SKY HIGH, LLC
    Inventors: John Goddard, Donald Picker, Samuil Umansky, Steven Price, Jac Wijkmans, Edward Boyd, Anthony Baxter
  • Publication number: 20060063738
    Abstract: The present invention provides therapeutic compositions containing lysophosphatidic acids, methods for making the compositions, and methods of use thereof.
    Type: Application
    Filed: September 26, 2005
    Publication date: March 23, 2006
    Applicant: Sky High, LLC
    Inventors: Ian Bathurst, Matthew Foehr, J. Goddard, Samuil Umansky, John Bradley, Donald Picker
  • Patent number: 6949529
    Abstract: The present invention provides therapeutic compositions containing lysophosphatidic acids, methods for making the compositions, and methods of use thereof.
    Type: Grant
    Filed: October 8, 2002
    Date of Patent: September 27, 2005
    Assignee: Sky High, LLC
    Inventors: Ian C. Bathurst, Matthew W. Foehr, J. Graham Goddard, Samiul R. Umansky, John D. Bradley, Donald H. Picker
  • Patent number: 6793945
    Abstract: The present invention provides methods for extracting anti-apoptotic compositions from various protein isolates and/or lipid mixtures with aqueous solutions not containing organic solvents. The compositions extracted by the methods can be used for a variety of purposes, including for therapeutic, nutritional and medicinal purposes.
    Type: Grant
    Filed: January 4, 2002
    Date of Patent: September 21, 2004
    Assignee: Sky High, LLC
    Inventors: Ian C. Bathurst, Matthew W. Foehr
  • Patent number: 6656729
    Abstract: The present invention is to methods of obtaining plant-derived compositions that inhibit apoptosis, the compositions obtained thereby, compositions comprising the composition, and methods of use thereof.
    Type: Grant
    Filed: October 23, 2001
    Date of Patent: December 2, 2003
    Assignee: Sky High, LLC
    Inventors: Ian Cyril Bathurst, John D. Bradley, L. David Tomei, Philip J. Barr
  • Publication number: 20030149002
    Abstract: The present invention provides therapeutic compositions containing lysophosphatidic acids, methods for making the compositions, and methods of use thereof.
    Type: Application
    Filed: October 8, 2002
    Publication date: August 7, 2003
    Applicant: SKY HIGH, LLC.
    Inventors: J. Graham Goddard, Samiul R. Umansky, John D. Bradley, Ian C. Bathurst, Matthew W. Foehr, Donald H. Picker
  • Patent number: 6500810
    Abstract: A method to inhibit inflammation in a mammal is disclosed. The method includes administering to the mammal a composition comprising a phospholipid, which can be lysophosphatidic acid. The administration of a phospholipid is believed to down regulate expression of adhesion molecules on the surface of vascular endothelial cells and circulating leukocytes of the mammal.
    Type: Grant
    Filed: December 14, 2000
    Date of Patent: December 31, 2002
    Assignee: Sky High, LLC
    Inventors: Allan M. Lefer, J. Graham Goddard
  • Patent number: 6495532
    Abstract: The present invention provides therapeutic compositions containing lysophosphotidic acids, methods for making the compositions, and methods of using the compositions in the preservation and treatment of organs.
    Type: Grant
    Filed: February 28, 2000
    Date of Patent: December 17, 2002
    Assignee: Sky High, LLC
    Inventors: Ian C. Bathurst, Matthew W. Foehr, J. Graham Goddard, Samiul R. Umansky, John D. Bradley, Donald H. Picker
  • Publication number: 20020155183
    Abstract: The present invention provides methods for extracting anti-apoptotic compositions from various protein isolates and/or lipid mixtures with aqueous solutions not containing organic solvents. The compositions extracted by the methods can be used for a variety of purposes, including for therapeutic, nutritional and medicinal purposes.
    Type: Application
    Filed: January 4, 2002
    Publication date: October 24, 2002
    Applicant: Sky High, LLC.
    Inventors: Ian C. Bathurst, Matthew W. Foehr
  • Publication number: 20020110608
    Abstract: The present invention is to methods of obtaining plant-derived compositions that inhibit apoptosis, the compositions obtained thereby, compositions comprising the composition, and methods of use thereof.
    Type: Application
    Filed: October 23, 2001
    Publication date: August 15, 2002
    Applicant: Sky High, LLC.
    Inventors: Ian Cyril Bathurst, John D. Bradley, L. David Tomei, Philip J. Barr
  • Patent number: 6413556
    Abstract: The present invention provides methods for extracting anti-apoptotic compositions from various protein isolates and/or lipid mixtures with aqueous solutions not containing organic solvents. The compositions extracted by the methods can be used for a variety of purposes, including for therapeutic, nutritional and medicinal purposes.
    Type: Grant
    Filed: January 7, 2000
    Date of Patent: July 2, 2002
    Assignee: Sky High, LLC
    Inventors: Ian C. Bathurst, Matthew W. Foehr
  • Patent number: 6321909
    Abstract: A composition comprising a storage-stable organ preservation solution, comprising a linear polyethylene glycol having an average molecular weight of approximately 20,000 Daltons and being essentially free of decomposition products. This solution can be used for organ preservation as a perfusate in a process in which the perfusate is flowed through the circulatory system of the organ, and can also be used for transplantation or routine open heart cardioplegic applications. The composition can be contained in a system comprising a means for preventing light exposure, especially UV light, to the solution. In addition, the system is preferably impervious to gases, particularly oxygen.
    Type: Grant
    Filed: February 12, 1998
    Date of Patent: November 27, 2001
    Assignee: Sky High, LLC
    Inventors: Winston Wicomb, Geoffrey Collins, Ian Bathurst, Matthew Foehr