Patents Assigned to Societe D'etudes et de Recherches Biologiques
  • Method for the preparation of high purity substituted benz ?E! indoles and the alkaline salts thereof
    Patent number: 5750722
    Abstract: Method for the preparation of high purity substituted benz?e!indoles corresponding to the general formula ##STR1## comprising the preparation of an arylhydrazine which is subjected to a Fischer indole synthesis with a suitable ketone, the benz?e!indole thus obtained being reacted with a radical R.sub.6, followed by subjection to a purification step.This method may more particularly be applied to the synthesis of Indocyanine Green.
    Type: Grant
    Filed: March 15, 1996
    Date of Patent: May 12, 1998
    Assignee: Societe D'etudes et de Recherches Biologiques
    Inventors: Anh Hoa Huynh, Joanne Tran, Fran.cedilla.ois Scherninski, Jean-Paul Guette