Abstract: The invention relates to a prosthesis (1) comprising a textile (2) of elongate shape defining a longitudinal axis A, and a resilient frame (3) connected to said textile along substantially the peripheral edge of the textile, said frame forming, in the area of each short side of the textile, at least one U-shaped bend (4) extending in the direction of the longitudinal axis, said frame being able to adopt an unstressed configuration, in which said textile is deployed, and a stressed configuration, in which said frame is subjected to a radial force directed towards said longitudinal axis and said textile forms at least one longitudinal fold.

Abstract: A physical abdominal surgical simulation system including an abdominal model mimicking the biomechanical properties and response of a patient specific abdomen and an image acquisition and analysis system. The abdominal model includes an abdominal wall model insert forming a frame of the abdominal model, an abdominal wall member secured to the abdominal wall model insert, a back member secured to the abdominal wall model insert in opposed relation with respect to the abdominal wall member, and an abdominal model cavity defined within abdominal wall model insert, the abdominal wall member, and the back member. The image acquisition and analysis system includes a plurality of cameras configured to capture images of the abdominal model cavity.

Abstract: An implant for the prevention or treatment of a hernia in the proximity of an organ stoma formed in an abdominal wall includes a porous structure having a surface intended to face the abdominal cavity covered by a first film of anti-adhesive material. The porous structure includes a first part intended to be in contact with a stoma organ and having a first thickness, and a second part having a second thickness greater than the first thickness, the first part including a surface intended to face the abdominal wall covered by a second film of anti-adhesive material.

Abstract: Method for preparing a chitosan-based porous layer The present invention relates to a method or preparing a chitosan-based, neutralized compressed porous layer, comprising the following steps: —a) a chitosan solution is prepared, —b) said solution is poured into a mold in order to form a layer, —c) the layer obtained in b) is lyophilized so as to obtain a porous layer, —d) said porous layer obtained in c) is compressed, —e) the compressed porous layer obtained in d) is neutralized by means of an NH4OH solution. It also relates to an implant comprising a layer obtained according to such a method.

Abstract: The present invention relates to a prosthetic knit based on at least a first yarn of biocompatible polymer material defining first and second opposite and openwork faces, and on at least a second biocompatible and heat-fusible monofilament yarn, forming barbs that protrude outwards from at least said first face and are obtained by melting loops generated by said second yarn, the chart followed for the knitting of said first and second yarns on a warp knitting machine having three guide bars B1, B2, B3 being the following, according to the ISO 11676 standard:—Bar B1: 1.0/0.1//—Bar B2: 1.0/7.7/6.6/7.7//—Bar B3: 2.1/5.5/3.4/0.0// said second yarn following the chart of bar B3. The present invention also relates to a process for manufacturing such a knit.

Abstract: The present invention relates to a device (1) for introducing a flexible prosthesis into a surgical incision, comprising a globally tubular body (2) having a proximal end (2a) and a distal end (2b), said tubular body being designed for receiving the prosthesis in a folded configuration in a sliding way, wherein the tubular body is provided with an open longitudinal slit (3) extending from said proximal end (2a) to said distal end (2b), and wherein said distal end is provided with a distal semi-tubular rounded extension (2c).

Abstract: The present invention relates to an implant (10) comprising: —a substrate (1) the surface of which comprising oxidized cellulose, said oxidized cellulose having a degree of oxidation ranging from 0.0 to 1, and —a multilayer coating covering said substrate, said multilayer coating comprising at least a first layer (2) adjacent said substrate, said first layer being formed of chitosan, and a second layer (3) adjacent said first layer, said second layer being formed of oxidized cellulose having a degree of oxidation ranging from 0.5 to 1. The invention further relates to a method for preparing such an implant.

Abstract: The present invention relates to a process for preparing a porous layer of biocompatible polymer, having a uniform density and porosity, comprising the following steps: a) a quantity Qp of solution of the said polymer, having a viscosity Vp, is poured into a mold in order to form a first sublayer, the surface of the first sublayer being left to the open air; b) a quantity Qs of solvent, having a viscosity Vs, lower than Vp, is spread uniformly over the surface of the first sublayer so as to form a second sublayer; c) the first and second sublayers are subjected to a step of lyophilization, in which the said polymer is a polysaccharide chosen from hyaluronic acid, alginic acid and chitosan, salts thereof and mixtures thereof.

Abstract: The invention relates to a prosthesis (1) comprising a textile (2) of elongate shape defining a longitudinal axis A, and a reinforcing element comprising at least one semi-rigid elongate structure (8) connected to said textile, said structure being substantially parallel to said longitudinal axis A and having a distal end provided with at least one fastening element (4) distinct from said textile and capable of cooperating with a part of a tool (10) that is able to pass through said trocar, in order to temporarily couple said prosthesis to said tool.

Abstract: The present invention relates to an openwork prosthetic knit (1) made from a single piece based on first yarns of biocompatible polymer materials that define a first face (2) and a second face that are opposite one another and on a second biocompatible yarn that generates barbs (3) that protrude outwards from at least said first face, characterized in that said first face comprises at least one zone in which it is provided with said barbs and at least one zone (5) in which it is free of such barbs. It also relates to a process for manufacturing such a knit (1) and to a prosthesis comprising such a knit (1).

Abstract: The present invention relates to a method for preparing a chitosan-based matrix comprising the following steps: a) two separate chitosan porous layers obtained from lyophilization of layers of one or more solutions of chitosan are provided, b) the chitosan porous layers of a) are neutralized and washed, c) a face of each chitosan porous layer is acidified with an acid, d) a fiber reinforcement member is provided and positioned between the two acidified faces of the two chitosan porous layers, e) the two chitosan porous layers and the fiber reinforcement member are let to dry to obtain a matrix having the fiber reinforcement member embedded therein. The invention also relates to an implant comprising a matrix obtained according to such a method.

Abstract: The invention relates to a method for forming a barbed suture (10) comprising: a) producing a knit by knitting together i) a set of chain stitch yarns (1) producing chain stitches and ii) a set of monofilament weft yarns completing weft stitches with at least one of said chain stitches, thereby producing at least one weft stitched chain stitch (6), b) cutting the knit along the warp direction on both sides of said weft stitched chain stitch, so as to isolate said weft stitched chain stitch from the rest of the produced knit, the chain stitch yarn of said at least one weft stitched chain stitch forming the elongate body (9) of the barbed suture and the monofilament cuts (7) extending from said weft stitches of said one weft stitched chain stitch forming the barbs (8) of said barbed suture.

Abstract: A system for assessing the distribution of shear forces at fixation points on a textile-based implant includes a tissue model, a load simulation device, and an analysis system. The tissue model includes an upper surface defining an opening therethrough and a fixation support configured to secure a textile-based implant against the upper surface at a plurality of fixation points defined along a plane of the upper surface. The load simulation device is configured to apply a load to a textile-based implant that is secured to the tissue model. A marker is disposed on the fixation support at one or more of the plurality of fixation points. The analysis system is configured to calculate a shear force vector at each of the fixation points where a marker is disposed in response to the load applied by the load simulation device.

Abstract: A packaging member for a hernia repair device including a surgical mesh and at least one grasping member. The packaging member includes a central portion configured to receive the surgical mesh, at least one recessed track section configured to receive the at least one grasping member, and a knob extending into the at least one recessed track section. The knob is configured to retain the at least one grasping member within the at least one recessed track section.

Abstract: A method for closing a wound in tissue is provided which includes providing a surgical fastener having a plurality of reactive members of a specific binding pair attached on a surface of the surgical fastener, and providing tissue with a plurality of complementary reactive members of the specific binding pair, wherein upon contact of the reactive members on the surface of the surgical fastener with the complimentary reactive members on the tissue, covalent bonds are formed between the reactive members and the complementary reactive members, thus adhering the device to the tissue.

Abstract: The present invention relates to a prosthesis (1) for the repair of an inguinal hernia, which prosthesis (1) is intended to be implanted by a posterior or open laparoscopic route and comprises: an openworked textile (2) made of biocompatible material, comprising a first face (2a) intended to be placed facing the biological tissues of the inguinal region, and a second face (2b) arranged opposite said first face and intended to be placed facing the peritoneum, said first face being provided with fastening means that are able to fix said textile in said biological tissues of the inguinal region, characterized in that at least a part of said second face (2b) is covered with a non-porous coating (7) composed of a material that is hydrosoluble at 37° C. and non-hydrosoluble at 25° C. The invention also relates to a method for producing such a prosthesis.

Abstract: The present invention relates to a prosthesis (10) intended to be implanted at an implantation site, comprising i) at least one fabric called the base fabric (2) having at least one apertured surface (3), ii) and at least one patch (4) provided with at least one barb (5) projecting from one of its surfaces and grippingly fastening said patch to said apertured surface of said base fabric at a specific place on said surface, said patch comprising at least one radiopaque element. The invention also relates to a kit comprising a fabric and a patch.

Abstract: The invention relates to a device (1) and method for selecting the size and shape of a prosthesis and/or for determining the location of marks to be made on the external face of the skin of a patient intended to receive such a prosthesis, for example for repairing a hernia, comprising a sheet (2) of transparent material, the said sheet comprising: —a plurality of graphical representations (3a, 3b, 4a, 4b, 5a, 5b, 5c, 5d) concentrically embodying the respective outlines of various shapes and sizes of prosthesis, —a plurality of first holes (6a, 6b, 6c, 6d, 6e, 7a, 7b, 7c, 7d, 7e) arranged along the transverse line passing through the center of the said sheet, and—a plurality of second holes (8a, 8b, 8c, 8d, 8e, 8f, 8g, 9a, 9b, 9c, 9d, 9e, 9f, 9g) arranged along the longitudinal line passing through the center (C) of the said sheet.

Abstract: An implant and a process for preparing such an implant are disclosed. The implant includes a porous layer including collagen, a non-porous layer including a collagenic constituent, and a reinforcement component. The non-porous layer is joined to the porous layer and the reinforcement member is embedded into the non-porous layer. The porous layer has a three dimensional density ranging from about 20 mg collagen/cm3 to about 200 mg collagen/cm3.

Abstract: The present invention relates to a method for preparing a neutralized matrix of non-antigenic collagenous material comprising the steps of: —a) preparing an acidic solution of non-antigenic collagenous material, —b) pouring the solution of a) into a mold in order to form a layer, —c) lyophilizing the layer of b) in order to obtain an acidic matrix of non-antigenic collagenous material, d) sterilizing the acidic matrix obtained in c) with ethylene oxide in order to obtain a neutralized matrix of non-antigenic collagenous material. The invention also relates to the matrices obtained and to surgical implants comprising such matrices.