Patents Assigned to Spinal Restoration, Inc.
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Publication number: 20140052070Abstract: A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises an anesthetic, fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.Type: ApplicationFiled: February 6, 2013Publication date: February 20, 2014Applicant: SPINAL RESTORATION, INC.Inventor: SPINAL RESTORATION, INC.
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Patent number: 8419722Abstract: An apparatus for percutaneous delivery of a sealant comprising: at least two fluid reservoirs, an introducer needle having a distal tip that is in fluid communication with at least one reservoir, a fluid delivery tube that is in fluid communication with a second reservoir, wherein the fluid delivery tube has a tip and wherein the fluid delivery tube is configured so that the tip of the fluid delivery tube does not extend past the distal tip of the introducer needle during use.Type: GrantFiled: January 5, 2007Date of Patent: April 16, 2013Assignee: Spinal Restoration, Inc.Inventors: Mark Richards, Brian D. Burkinshaw, Kevin Pauza, James B. Rogan, John Wheeler
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Patent number: 8403895Abstract: A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises an anesthetic, fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.Type: GrantFiled: October 5, 2009Date of Patent: March 26, 2013Assignee: Spinal Restoration, Inc.Inventors: Kevin Pauza, Brian D. Burkinshaw, Steven I. Whitlock, Mark I. Richards, James B. Rogan
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Patent number: 8403923Abstract: A method and kit for treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.Type: GrantFiled: August 17, 2005Date of Patent: March 26, 2013Assignee: Spinal Restoration, Inc.Inventors: Steven I. Whitlock, Brian D. Burkinshaw, Kevin Pauza
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Patent number: 8394072Abstract: A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises an anesthetic, fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.Type: GrantFiled: October 5, 2009Date of Patent: March 12, 2013Assignee: Spinal Restoration, Inc.Inventors: Kevin Pauza, Brian D. Burkinshaw, Steven I. Whitlock, Mark I. Richards, James B. Rogan
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Patent number: 8357147Abstract: A method of repairing a defect in an annulus fibrosus of an intervertebral disc, without excising the entire nucleus pulposus of the disc. The method includes inserting an introducer needle through the annulus fibrosus by puncturing the annulus fibrosus with the introducer needle, injecting an in situ curable, bio-compatible polymerizable or polymeric material composition into the disc through the introducer needle directly or indirectly so that the in situ curable composition contacts a defect in the annulus fibrosus; and curing said material in situ.Type: GrantFiled: February 16, 2007Date of Patent: January 22, 2013Assignee: Spinal Restoration, Inc.Inventors: Brian D. Burkinshaw, John L. Wheeler, James B. Rogan, Steven I. Whitlock
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Patent number: 8206448Abstract: A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, wherein the fibrinogen, the activating compound or both has been reconstituted with a solution containing at least one additive, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.Type: GrantFiled: August 17, 2005Date of Patent: June 26, 2012Assignee: Spinal Restoration, Inc.Inventors: Brian D. Burkinshaw, Steven I. Whitlock, Kevin Pauza, Mark I. Richards, James B. Rogan
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Patent number: 8124075Abstract: The invention includes a composition useful for preparing a tissue sealant for use on a patient, comprising: autologous fibrinogen, an activating agent and at least one supplement. The invention includes a method of treating a disc having at least one defect, comprising: introducing a composition into the disc, wherein the composition comprises autologous fibrinogen and an activating agent, and wherein the composition forms fibrin.Type: GrantFiled: July 14, 2005Date of Patent: February 28, 2012Assignee: Spinal Restoration, Inc.Inventors: Brian D. Burkinshaw, Steven I. Whitlock, James B. Rogan, Gerald L. Devries
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Patent number: 8047407Abstract: A device for delivery of biologic materials, comprising: a cartridge having at least two cylinder bores for fluids to be delivered, wherein each cylinder includes an exit port for a fluid, a plunger within each cylinder for pushing the fluids out of the cylinder, a housing adapted to receive the cartridge, wherein the housing or cartridge includes an adaptor to receive and lock a manifold that operably connects to the exit ports of the cartridge, at least two toothed rams, wherein each toothed ram is at least partially within a cylinder bore, a trigger connected to the housing, wherein the trigger includes a toothed drive rack, a toothed wheel assembly that cooperates with the toothed drive rack and with the toothed rams, as well as methods of making the device, methods of using the device to treat discs, kits including the device.Type: GrantFiled: October 24, 2007Date of Patent: November 1, 2011Assignee: Spinal Restoration, Inc.Inventors: John L. Wheeler, Gary Whipple, A. David Boccuti, Thomas T. Washburn, Andrew Nicholas Gentile, J. Brent Ratz, John Spiridigliozzi
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Patent number: 7597687Abstract: A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises an anesthetic, fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc.Type: GrantFiled: August 17, 2005Date of Patent: October 6, 2009Assignee: Spinal Restoration, Inc.Inventors: Kevin Pauza, Brian D. Burkinshaw, Steven I. Whitlock, Mark I. Richards, James B. Rogan
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Patent number: 7235255Abstract: The present invention relates generally to the preparation and use of biological tissue adhesives which rely on combining fibrinogen and thrombin. More particularly, the present invention relates to a method of preparing a fibrin sealant whereby said sealant is formed by reconstituting the fibrinogen or the thrombin component in the presence of biological and/or non-biological agents such as drugs, chemicals, and proteins. Preferably, these agents are introduced in solution, such as for example, a corticosteroid-containing solution like a betamethasone solution containing betamethasone acetate or betamethasone sodium phosphate; a triamicinolone solution; or a methylprednisolone solution. These solutions may be substituted for, or provided as a complement to, other solutions that are typically used in the preparation of fibrin sealants such as, for example, calcium chloride.Type: GrantFiled: December 3, 2004Date of Patent: June 26, 2007Assignee: Spinal Restoration, Inc.Inventors: Sam L. Austin, Thomas E. Davis
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Patent number: 7229633Abstract: The present invention relates generally to the preparation and use of biological tissue adhesives which rely on combining fibrinogen and thrombin. More particularly, the present invention relates to a method of preparing a fibrin sealant whereby said sealant is formed by reconstituting the fibrinogen or the thrombin component in the presence of biological and/or non-biological agents such as drugs, chemicals, and proteins. Preferably, these agents are introduced in solution, such as for example, a corticosteroid-containing solution like a betamethasone solution containing betamethasone acetate or betamethasone sodium phosphate; a triamicinolone solution; or a methylprednisolone solution. These solutions may be substituted for, or provided as a complement to, other solutions that are typically used in the preparation of fibrin sealants such as, for example, calcium chloride.Type: GrantFiled: December 4, 2004Date of Patent: June 12, 2007Assignee: Spinal Restoration, Inc.Inventors: Sam L. Austin, Thomas E. Davis
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Patent number: 6921532Abstract: The present invention relates generally to the preparation and use of biological tissue adhesives which rely on combining fibrinogen and thrombin. More particularly, the present invention relates to a method of preparing a fibrin sealant whereby said sealant is formed by reconstituting the fibrinogen or the thrombin component in the presence of biological and/or non-biological agents such as drugs, chemicals, and proteins. Preferably, these agents are introduced in solution, such as for example, a corticosteroid-containing solution like a betamethasone solution containing betamethasone acetate or betamethasone sodium phosphate; a triamicinolone solution; or a methylprednisolone solution. These solutions may be substituted for, or provided as a complement to, other solutions that are typically used in the preparation of fibrin sealants such as, for example, calcium chloride.Type: GrantFiled: October 22, 2002Date of Patent: July 26, 2005Assignee: Spinal Restoration, Inc.Inventors: Sam L. Austin, Thomas E. Davis