Patents Assigned to St. Joseph's Hospital and Medical Center
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Publication number: 20210052902Abstract: Disclosed herein are methods, systems, and apparatus for treating a medical condition of a patient, involving detecting a physiological cycle or cycles of the patient and applying an electrical signal to a portion of the patient's vagus nerve through an electrode at a selected point in the physiological cycle(s). The physiological cycle can be the cardiac and/or respiratory cycle. The selected point can be a point in the cardiac cycle correlated with increased afferent conduction on the vagus nerve, such as a point from about 10 msec to about 800 msec after an R-wave of the patient's ECG, optionally during inspiration by the patient. The selected point can be a point in the cardiac cycle when said applying increases heart rate variability, such as a point from about 10 msec to about 800 msec after an R-wave of the patient's ECG, optionally during expiration by the patient.Type: ApplicationFiled: November 6, 2020Publication date: February 25, 2021Applicant: Catholic Healthcare West (d/b/a St. Joseph's Hospital and Medical Center)Inventor: Arthur Craig
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Publication number: 20200306541Abstract: An implanted electrical signal generator delivers a novel exogenous electrical signal to a vagus nerve of a patient. The vagus nerve conducts action potentials originating in the heart and lungs to various structures of the brain, thereby eliciting a vagal evoked potential in those structures. The exogenous electrical signal simulates and/or augments the endogenous afferent activity originating from the heart and/or lungs of the patient, thereby enhancing the vagal evoked potential in the various structures of the brain. The exogenous electrical signal includes a series of electrical pulses organized or patterned into a series of microbursts including 2 to 20 pulses each. No pulses are sent between the microbursts. Each of the microbursts may be synchronized with the QRS wave portion of an ECG. The enhanced vagal evoked potential in the various structures of the brain may be used to treat various medical conditions including epilepsy and depression.Type: ApplicationFiled: June 13, 2020Publication date: October 1, 2020Applicant: Catholic Healthcare West (d/b/a St. Joseph's Hospital and Medical Center)Inventor: Arthur Craig
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Publication number: 20160158554Abstract: An implanted electrical signal generator delivers a novel exogenous electrical signal to a vagus nerve of a patient. The vagus nerve conducts action potentials originating in the heart and lungs to various structures of the brain, thereby eliciting a vagal evoked potential in those structures. The exogenous electrical signal simulates and/or augments the endogenous afferent activity originating from the heart and/or lungs of the patient, thereby enhancing the vagal evoked potential in the various structures of the brain. The exogenous electrical signal includes a series of electrical pulses organized or patterned into a series of microbursts including 2 to 20 pulses each. No pulses are sent between the microbursts. Each of the microbursts may be synchronized with the QRS wave portion of an ECG. The enhanced vagal evoked potential in the various structures of the brain may be used to treat various medical conditions including epilepsy and depression.Type: ApplicationFiled: February 16, 2016Publication date: June 9, 2016Applicant: Catholic Healthcare West (d/b/a St. Joseph's Hospital and Medical Center)Inventor: Arthur D. Graig
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Publication number: 20150352362Abstract: Disclosed herein are methods, systems, and apparatus for treating a medical condition in a patient using an implantable medical device by applying an electrical signal characterized by having a number of pulses per microburst, an interpulse interval, a microburst duration, and an interburst period to a portion of a cranial nerve of said patient, wherein at least one of the number of pulses per microburst, the interpulse interval, the microburst duration, or the interburst period is selected to enhance cranial nerve evoked potentials.Type: ApplicationFiled: August 20, 2015Publication date: December 10, 2015Applicant: Catholic Healthcare West (d/b/a St. Joseph's Hospital and Medical Center)Inventor: ARTHUR CRAIG
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Publication number: 20140222114Abstract: Disclosed herein are methods, systems, and apparatus for treating a medical condition of a patient, involving detecting a physiological cycle or cycles of the patient and applying an electrical signal to a portion of the patient's vagus nerve through an electrode at a selected point in the physiological cycle(s). The physiological cycle can be the cardiac and/or respiratory cycle. The selected point can be a point in the cardiac cycle correlated with increased afferent conduction on the vagus nerve, such as a point from about 10 msec to about 800 msec after an R-wave of the patient's ECG, optionally during inspiration by the patient. The selected point can be a point in the cardiac cycle when said applying increases heart rate variability, such as a point from about 10 msec to about 800 msec after an R-wave of the patient's ECG, optionally during expiration by the patient.Type: ApplicationFiled: April 9, 2014Publication date: August 7, 2014Applicant: Catholic Healthcare West (D/B/A St. Joseph's Hospital and Medical Center)Inventor: Arthur D. Craig
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Publication number: 20140163643Abstract: Disclosed herein are methods, systems, and apparatus for treating a medical condition in a patient using an implantable medical device by applying an electrical signal characterized by having a number of pulses per microburst, an interpulse interval, a microburst duration, and an interburst period to a portion of a cranial nerve of said patient, wherein at least one of the number of pulses per microburst, the interpulse interval, the microburst duration, or the interburst period is selected to enhance cranial nerve evoked potentials.Type: ApplicationFiled: November 25, 2013Publication date: June 12, 2014Applicant: Catholic Healthcare West (D/B/A St. Joseph's Hospital and Medical Center)Inventor: Arthur D. Craig
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Publication number: 20140128938Abstract: Disclosed herein are methods, systems, and apparatus for treating a medical condition in a patient using an implantable medical device by applying an electrical signal characterized by having a number of pulses per microburst, an interpulse interval, a microburst duration, and an interburst period to a portion of a cranial nerve of said patient, wherein at least one of the number of pulses per microburst, the interpulse interval, the microburst duration, or the interburst period is selected to enhance cranial nerve evoked potentials.Type: ApplicationFiled: January 10, 2014Publication date: May 8, 2014Applicant: atholic Healthcare West (D/B/A St. Joseph's Hospital and Medical Center)Inventor: Arthur D. Craig
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Publication number: 20130150357Abstract: The invention provides hydroxybupropion analogues capable of inhibiting the reuptake of one or more monoamines and/or acting as antagonists at nicotinic acetylcholine receptors. The compounds may selectively bind to one or more monoamine transporters, including those for dopamine, norepinephrine, and serotonin and/or may selectively bind to one or more nicotinic acetylcholine receptor subtypes. Such compounds may be used to treat conditions that are responsive to modification of monoamine levels and/or antagonism of nicotinic acetylcholine receptors, including drug dependency, depression, and obesity.Type: ApplicationFiled: November 19, 2012Publication date: June 13, 2013Applicants: Research Triangle Institute, Virginia Commonwealth University, Dignity Health d/b/a St. Joseph's Hospital and Medical Center and Barrow Neurological InstituteInventors: Research Triangle Institute, Digital Health d/b/a St. Joseph's Hospital and Med, Virginia Commonwealth University
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Publication number: 20100217154Abstract: An automated blood draw system operates in conjunction with an arterial or venous line. The aspiration mechanism allows the rate of aspiration, volume of aspirate, and the time interval of aspiration to be predetermined. Blood can be collected in sequential collection vials for subsequent analysis of a given laboratory parameter, or delivered directly to integrated analysis devices. While a predetermined volume of aspirate can be wasted, excessive aspiration is prevented by monitoring waste obtained in a collection receptacle. A flush system maintains the patency of the line without contamination of the specimen.Type: ApplicationFiled: February 26, 2009Publication date: August 26, 2010Applicant: Catholic Healthcare West (d/b/a) St. Joseph's Hospital and Medical CenterInventors: Vivek R. Deshmukh, Neil R. Crawford
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Publication number: 20100063563Abstract: Disclosed herein are methods, systems, and apparatus for treating a medical condition in a patient using an implantable medical device by applying an electrical signal characterized by having a number of pulses per microburst, an interpulse interval, a microburst duration, and an interburst period to a portion of a cranial nerve of said patient, wherein at least one of the number of pulses per microburst, the interpulse interval, the microburst duration, or the interburst period is selected to enhance cranial nerve evoked potentials.Type: ApplicationFiled: March 10, 2009Publication date: March 11, 2010Applicant: Catholic Healthcare West (d/b/a St.Joseph's Hospital and Medical Center)Inventor: Arthur D. Craig
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Publication number: 20090177252Abstract: Disclosed herein are methods, systems, and apparatus for treating a medical condition of a patient, involving detecting a physiological cycle or cycles of the patient and applying an electrical signal to a portion of the patient's vagus nerve through an electrode at a selected point in the physiological cycle(s). The physiological cycle can be the cardiac and/or respiratory cycle. The selected point can be a point in the cardiac cycle correlated with increased afferent conduction on the vagus nerve, such as a point from about 10 msec to about 800 msec after an R-wave of the patient's ECG, optionally during inspiration by the patient. The selected point can be a point in the cardiac cycle when said applying increases heart rate variability, such as a point from about 10 msec to about 800 msec after an R-wave of the patient's ECG, optionally during expiration by the patient.Type: ApplicationFiled: March 10, 2009Publication date: July 9, 2009Applicant: Catholic Healthcare West (d/b/a St. Joseph's Hospital and Medical Center)Inventor: Arthur D. Craig
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Publication number: 20090171405Abstract: An implanted electrical signal generator delivers a novel exogenous electrical signal to a vagus nerve of a patient. The vagus nerve conducts action potentials originating in the heart and lungs to various structures of the brain, thereby eliciting a vagal evoked potential in those structures. The exogenous electrical signal simulates and/or augments the endogenous afferent activity originating from the heart and/or lungs of the patient, thereby enhancing the vagal evoked potential in the various structures of the brain. The exogenous electrical signal includes a series of electrical pulses organized or patterned into a series of microbursts including 2 to 20 pulses each. No pulses are sent between the microbursts. Each of the microbursts may be synchronized with the QRS wave portion of an ECG. The enhanced vagal evoked potential in the various structures of the brain may be used to treat various medical conditions including epilepsy and depression.Type: ApplicationFiled: March 10, 2009Publication date: July 2, 2009Applicant: Catholic Healthcare West (d/b/a St. Joseph's Hospital and Medical Center)Inventor: Arthur D. Craig
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Publication number: 20080215181Abstract: A method and system for performing invasive procedures includes a surgical robot which is controlled by a guidance system that uses time of flight calculations from RF transmitters embedded in the robot, surgical instrument, and patient anatomy. Sensors around the room detect RF transmissions emitted by the RF transmitters and drive the robot according to a preprogrammed trajectory entered into the guidance system.Type: ApplicationFiled: August 27, 2007Publication date: September 4, 2008Applicant: Catholic Healthcare West (d/b/a St. Joseph's Hospital and Medical Center)Inventors: DAVID W. SMITH, Regina DeSanctis-Smith, Alan M. Pitt, Nicholas Theodore, Neil Crawford
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Publication number: 20080154389Abstract: A method and system for performing invasive procedures includes a surgical robot which is controlled by a guidance system that uses time of flight calculations from RF transmitters embedded in the robot, surgical instrument, and patient anatomy. Sensors around the room detect RF transmissions emitted by the RF transmitters and drive the robot according to a preprogrammed trajectory entered into the guidance system.Type: ApplicationFiled: August 13, 2007Publication date: June 26, 2008Applicant: Catholic Healthcare West (d/b/a St. Joseph's Hospital and Medical Center)Inventors: David W. Smith, Regina DeSanctis-Smith, Alan M. Pitt, Nicholas Theodore, Neil R. Crawford
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Publication number: 20070238985Abstract: The present invention concerns a system for utilizing radio frequency signals to dynamically determine the location of a medical device throughout a procedure and to improve navigation of the medical device. For these purposes, a plurality of RF receivers are mounted at operative locations in the operating room and operate on the same clock signal. The system also utilizes a diagnostic medical image such as an MRI, and overlays the position feedback signal on the image. This allows, for example, a surgeon to pick a desired spot on the diagnostic image, and then cause a robotic arm driven device to be moved to that particular spot inside the human body.Type: ApplicationFiled: February 16, 2007Publication date: October 11, 2007Applicant: Catholic Healthcare West (d/b/a St. Joseph's Hospital and Medical Center)Inventors: David Smith, Regina DeSanctis-Smith, Alan Pitt, Nicholas Theodore, Neil Crawford
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Publication number: 20070233192Abstract: An implanted electrical signal generator delivers a novel exogenous electrical signal to a vagus nerve of a patient. The vagus nerve conducts action potentials originating in the heart and lungs to various structures of the brain, thereby eliciting a vagal evoked potential in those structures. The exogenous electrical signal simulates and/or augments the endogenous afferent activity originating from the heart and/or lungs of the patient, thereby enhancing the vagal evoked potential in the various structures of the brain. The exogenous electrical signal includes a series of electrical pulses organized or patterned into a series of microbursts including 2 to 20 pulses each. No pulses are sent between the microbursts. Each of the microbursts may be synchronized with the QRS wave portion of an ECG. The enhanced vagal evoked potential in the various structures of the brain may be used to treat various medical conditions including epilepsy and depression.Type: ApplicationFiled: March 29, 2007Publication date: October 4, 2007Applicant: Catholic Healthcare West (d/b/a St. Joseph's Hospital and Medical Center)Inventor: Arthur D. Craig
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Publication number: 20070233193Abstract: Disclosed herein are methods, systems, and apparatus for treating a medical condition in a patient using an implantable medical device by applying an electrical signal characterized by having a number of pulses per microburst, an interpulse interval, a microburst duration, and an interburst period to a portion of a cranial nerve of said patient, wherein at least one of the number of pulses per microburst, the interpulse interval, the microburst duration, or the interburst period is selected to enhance cranial nerve evoked potentials.Type: ApplicationFiled: March 29, 2007Publication date: October 4, 2007Applicant: Catholic Healthcare West (d/b/a St. Joseph's Hospital and medical Center)Inventor: Arthur D. Craig
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Publication number: 20070233194Abstract: Disclosed herein are methods, systems, and apparatus for treating a medical condition of a patient, involving detecting a physiological cycle or cycles of the patient and applying an electrical signal to a portion of the patient's vagus nerve through an electrode at a selected point in the physiological cycle(s). The physiological cycle can be the cardiac and/or respiratory cycle. The selected point can be a point in the cardiac cycle correlated with increased afferent conduction on the vagus nerve, such as a point from about 10 msec to about 800 msec after an R-wave of the patient's ECG, optionally during inspiration by the patient. The selected point can be a point in the cardiac cycle when said applying increases heart rate variability, such as a point from about 10 msec to about 800 msec after an R-wave of the patient's ECG, optionally during expiration by the patient.Type: ApplicationFiled: March 29, 2007Publication date: October 4, 2007Applicant: Catholic Healthcare West (d/b/a St. Joseph's Hospital and Medical Center)Inventor: Arthur D. Craig
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Patent number: 7176684Abstract: The present invention is directed to a method of MR imaging whereby a k-space blade extending through a center of k-space from a subject in motion is acquired. A high-pass convolution of the k-space blade with a reference k-space blade is then determined and converted to a ? function. In-plane motion of the subject during data acquisition of the k-space is then determined from the ? function.Type: GrantFiled: June 29, 2005Date of Patent: February 13, 2007Assignees: General Electric Company, Catholic Healthcare West, California Nonprofit Public Benefit Corporation, d/ba St. Joseph's Hospital and Medical CenterInventors: Sarah K. Patch, Michael R. Hartley, James G. Pipe
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Publication number: 20020191000Abstract: A system and method for creating and viewing stereoscopic sequences of an environment. A virtual reality experience is provided to a user that can be used for various applications. These applications include, but are not limited to, surgery. In a method according to one embodiment of the present invention, interactive stereoscopic sequences of an environment are created, by: (a) positioning an image capturing device with respect to the environment; (b) capturing at least two two-dimensional images of at least a portion of the environment using the image capturing device; and (c) repeating steps (a) and (b) for a plurality of positions of interest; wherein the images are a spatially ordered part of the same environment and can be viewed as part of an interactive experience.Type: ApplicationFiled: June 14, 2001Publication date: December 19, 2002Applicant: St. Joseph's Hospital and Medical CenterInventor: Jeffrey S. Henn