Patents Assigned to Stanford Rook Limited
  • Immunotherapeutic agent
    Patent number: 7569213
    Abstract: The invention relates to a compound which is an ester of 1,2,3-propanetriol with one or more C11 to C24 fatty acids, wherein at least one fatty acid has at least one double bond. The compound is useful in the treatment of chronic inflammatory disorders.
    Type: Grant
    Filed: November 22, 2005
    Date of Patent: August 4, 2009
    Assignee: Stanford Rook Limited
    Inventors: Laura Rosa Brunet, Graham Rook
  • Mycobacterium vaccae for down-regulation of the Th2 activity of the immune system
    Patent number: 6878377
    Abstract: Antigenic and/or immunogenic material derived from Mycobacterium vaccae is used to down-regulate Th2 activity of the immune system without up-regulation of Th1 activity. Disorders such as Chronic Fatigue Syndrome, Gulf War Syndrome and Total Allergy Syndrome are treated. The material preferably comprises dead M. vaccae cells in a composition which does not include a non-M. vaccae antigen, immunogen or allergen.
    Type: Grant
    Filed: January 18, 2001
    Date of Patent: April 12, 2005
    Assignee: Stanford Rook Limited
    Inventors: Graham A. Rook, John L. Stanford, Alimuddin L. Zumla
  • Treatment of chronic viral infections with M. vaccae
    Patent number: 6596282
    Abstract: The present invention provides the use of an M. vaccae preparation for the manufacture of a medicament for use in the treatment of a chronic viral infection, excluding an HIV infection. Chronic viral infections include HPV infection, such as HPV infection associated with cervical dysplasia, herpes virus infection, subacute sclerosing pan-encephalitis and hepatitis virus infection.
    Type: Grant
    Filed: September 13, 2001
    Date of Patent: July 22, 2003
    Assignee: Stanford Rook Limited
    Inventors: John L. Stanford, Graham A. W. Rook, Cynthia A. Stanford
  • Prophylactic and therapeutic method
    Patent number: 6432714
    Abstract: Antigenic and/or immunoregulatory material derived from Mycobacterium vaccae is useful in the prophylaxis or therapy of AIDS with or without associated tuberculosis.
    Type: Grant
    Filed: February 27, 2001
    Date of Patent: August 13, 2002
    Assignee: Stanford Rook Limited
    Inventors: John Lawson Stanford, Graham A. W. Rook
  • Mycobacterium vaccae for down-regulation of the Th2 activity of the immune system
    Publication number: 20010018057
    Abstract: Antigenic and/or immunogenic material derived from Mycobacterium vaccae is used to down-regulate Th2 activity of the immune system without up-regulation of Th1 activity. Disorders such as Chronic Fatigue Syndrome, Gulf War Syndrome and Total Allergy Syndrome are treated. The material preferably comprises dead M. vaccae cells in a composition which does not include a non-M. vaccae antigen, immunogen or allergen.
    Type: Application
    Filed: January 18, 2001
    Publication date: August 30, 2001
    Applicant: STANFORD ROOK LIMITED
    Inventors: Graham A. Rook, John L. Stanford, Alimuddin L. Zumla
  • Immunotherapeutic agent and its use
    Patent number: 6056964
    Abstract: A method for delaying or preventing the growth or spread of a malignant neoplasm by administering to a subject in need material which comprises killed cells of Mycobacterium vaccae in an amount sufficient at least to delay or prevent the growth or spread of the neoplasm.
    Type: Grant
    Filed: October 25, 1996
    Date of Patent: May 2, 2000
    Assignee: Stanford Rook Limited
    Inventors: Graham Arthur William Rook, John Lawson Stanford