Patents Assigned to STELIS BIOPHARMA PRIVATE LIMITED
  • Insulin production methods and proinsulin constructs
    Patent number: 10100098
    Abstract: Novel proinsulins and glargine, aspart and Lis-Pro proinsulin analogs having specific amino acid and/or nucleic acid modifications suitable for improved methods of insulin production, as well as novel and highly efficient processes for preparing the same. The novel proinsulins and proinsulin analogs may be converted into human insulin and insulin analogs, respectively, that are useful in therapeutic preparations.
    Type: Grant
    Filed: January 27, 2016
    Date of Patent: October 16, 2018
    Assignee: Stelis Biopharma Private Limited
    Inventors: Ronald E. Zimmerman, David John Stokell, Michael Patrick Akers
  • ASPART PROINSULIN COMPOSITIONS AND METHODS OF PRODUCING ASPART INSULIN ANALOGS
    Publication number: 20160024168
    Abstract: Aspart modified proinsulin sequences that have a modified C-peptide amino acid and/or nucleic acid modification for producing aspart insulin analogs are provided. Highly efficient processes for preparing the aspart insulin analogs and improved preparations containing the aspart insulin analogs prepared according to the methods described herein are also provided.
    Type: Application
    Filed: May 29, 2015
    Publication date: January 28, 2016
    Applicant: STELIS BIOPHARMA PRIVATE LIMITED
    Inventors: Ronald E. ZIMMERMAN, David J. STOKELL, Michael P. AKERS