Patents Assigned to STEM ARTS PROJECTS, LLC
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Patent number: 10927402Abstract: A capsule to store and deliver lyophilized reagents is described. The lyophilized reagent capsule is configured to store a lyophilized reagent for at least five days, and is further configured to deliver a lyophilized reagent to a biological sample. The capsule includes a top, a bottom, and a lyophilized reagent. A method for delivering the lyophilized reagent via the capsule and without the use of pipettes to deliver the lyophilized reagents is described. The capsule may be part of a lyophilized reagent capsule kit.Type: GrantFiled: April 10, 2018Date of Patent: February 23, 2021Assignee: STEM Arts Projects, LLCInventors: Abraham Oommen, Heather Piscatelli, Molly Manning, Alyssa Hangman
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Publication number: 20200199661Abstract: Reaction condition compositions for detecting a genomic variation from a small sample amount from 5 nano grams (ng) to 1 microgram (ug) includes DNA ligase, DNA polymerase, at least one COP, a DNA polymerase buffer, NAD+, at least two primers, and deoxynucleotide triphosphates (dNTPs). Detection of the genomic variation utilizes COPs with increased ligation efficiency and RCA with fluorescence detection due to simultaneous ligation of COPs to CPs and replication of the genomic variation. The reaction condition composition eliminates the need to perform background reduction of un-hybridized or un-ligated COPs.Type: ApplicationFiled: January 11, 2019Publication date: June 25, 2020Applicant: STEM ARTS PROJECTS, LLCInventors: Abraham Oommen, Heather Piscatelli, Alyssa Hangman
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Publication number: 20190309344Abstract: A capsule to store and deliver lyophilized reagents is described. The lyophilized reagent capsule is configured to store a lyophilized reagent for at least five days, and is further configured to deliver a lyophilized reagent to a biological sample. The capsule includes a top, a bottom, and a lyophilized reagent. A method for delivering the lyophilized reagent via the capsule and without the use of pipettes to deliver the lyophilized reagents is described. The capsule may be part of a lyophilized reagent capsule kit.Type: ApplicationFiled: April 10, 2018Publication date: October 10, 2019Applicant: Stem Arts Projects, LLCInventors: Abraham Oommen, Heather Piscatelli, Molly Manning, Alyssa Hangman
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Patent number: 9957500Abstract: A continuous flow nucleic acid extraction apparatus comprising a piston column apparatus for the extraction of nucleic acids from a nucleic acid sample. The disclosure also includes a method of using the continuous flow nucleic acid extraction apparatus.Type: GrantFiled: February 26, 2015Date of Patent: May 1, 2018Assignee: Stem Arts Projects, LLCInventors: Abraham Oommen, Matthew Greenleaf, Adam Koch
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Publication number: 20180105809Abstract: A portable nucleic acid extraction kit includes a portable nucleic acid extraction apparatus, at least one lysis buffer, at least one binding buffer, at least one washing buffer, at least one elution buffer, and at least three kit sample tubes. The portable nucleic acid extraction apparatus includes a handle, a rod, a tip, and may include a nucleic acid binding medium. The method of using the portable nucleic acid extraction apparatus includes, treating a biological sample having a nucleic acid, binding the nucleic acid in the treated biological sample to the tip of the portable nucleic acid extraction apparatus, incubating the tip of the portable nucleic acid extraction apparatus bound with the nucleic acid, washing the tip of the portable nucleic acid apparatus bound with the nucleic acid, eluting the bound nucleic acid, and analyzing the eluted nucleic acid.Type: ApplicationFiled: August 10, 2016Publication date: April 19, 2018Applicant: STEM ARTS PROJECTS, LLCInventors: Abraham Oommen, Andrew Rush, Heather Piscatelli, Seth Lewin, Brandon Hatch
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Patent number: 9810631Abstract: A wavelength scanning apparatus that detects at least four different fluorescent emission wavelengths simultaneously or nearly simultaneously is described. The wavelength scanning apparatus includes a heating block having at least four sample wells, each sample well configured for receiving a sample, at least four excitation activation apertures, and at least four fluorescence emission discharge apertures. The wavelength scanning apparatus also includes an analysis scanner having at least four light sources, where the at least four light sources excite at least four fluorophores, at least four excitation light filters that filter out light except that of the desired excitation wavelength/s, at least four fluorescence emission light filters that filter out light except that of the desired fluorescent emission wavelengths, and at least four photodetectors to detect light of the desired fluorescent emission wavelengths.Type: GrantFiled: November 1, 2016Date of Patent: November 7, 2017Assignee: STEM ARTS PROJECTS, LLCInventors: Abraham Oommen, Matthew Greenleaf, Adam Koch, Amitabha Sarkar
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Publication number: 20170115222Abstract: A wavelength scanning apparatus that detects at least four different fluorescent emission wavelengths simultaneously or nearly simultaneously is described. The wavelength scanning apparatus includes a heating block having at least four sample wells, each sample well configured for receiving a sample, at least four excitation activation apertures, and at least four fluorescence emission discharge apertures. The wavelength scanning apparatus also includes an analysis scanner having at least four light sources, where the at least four light sources excite at least four fluorophores, at least four excitation light filters that filter out light except that of the desired excitation wavelength/s, at least four fluorescence emission light filters that filter out light except that of the desired fluorescent emission wavelengths, and at least four photodetectors to detect light of the desired fluorescent emission wavelengths.Type: ApplicationFiled: November 1, 2016Publication date: April 27, 2017Applicant: STEM ARTS PROJECTS, LLCInventors: Abraham Oommen, Matthew Greenleaf, Adam Koch, Amitabha Sarkar
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Patent number: 9568429Abstract: A wavelength scanning apparatus that detects at least four different florescent emission wavelengths simultaneously or nearly simultaneously is described. The wavelength scanning apparatus includes a heating block having at least four sample wells, each sample well configured for receiving a sample, at least four excitation activation apertures, and at least four fluorescence emission discharge apertures. The wavelength scanning apparatus also includes an analysis scanner having at least four light sources, where the at least four light sources excite at least four fluorophores, at least four excitation light filters that filter out light except that of the desired excitation wavelength/s, at least four fluorescence emission light filters that filter out light except that of the desired florescent emission wavelengths, and at least four photodetectors to detect light of the desired florescent emission wavelengths.Type: GrantFiled: July 25, 2015Date of Patent: February 14, 2017Assignee: Stem Arts Projects, LLCInventors: Abraham Oommen, Matthew Greenleaf, Adam Koch, Amitabha Sarkar
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Publication number: 20170023479Abstract: A wavelength scanning apparatus that detects at least four different florescent emission wavelengths simultaneously or nearly simultaneously is described. The wavelength scanning apparatus includes a heating block having at least four sample wells, each sample well configured for receiving a sample, at least four excitation activation apertures, and at least four fluorescence emission discharge apertures. The wavelength scanning apparatus also includes an analysis scanner having at least four light sources, where the at least four light sources excite at least four fluorophores, at least four excitation light filters that filter out light except that of the desired excitation wavelength/s, at least four fluorescence emission light filters that filter out light except that of the desired florescent emission wavelengths, and at least four photodetectors to detect light of the desired florescent emission wavelengths.Type: ApplicationFiled: July 25, 2015Publication date: January 26, 2017Applicant: STEM ARTS PROJECTS, LLCInventors: Abraham Oommen, Matthew Greenleaf, Adam Koch, Amitabha Sarkar
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Publication number: 20160251647Abstract: A continuous flow nucleic acid extraction apparatus comprising a piston column apparatus for the extraction of nucleic acids from a nucleic acid sample. The disclosure also includes a method of using the continuous flow nucleic acid extraction apparatus.Type: ApplicationFiled: February 26, 2015Publication date: September 1, 2016Applicant: STEM ARTS PROJECTS, LLCInventors: Abraham Oommen, Matthew Greenleaf, Adam Koch
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Patent number: D786707Type: GrantFiled: January 19, 2016Date of Patent: May 16, 2017Assignee: Stem Arts Projects, LLCInventors: Abraham Oommen, Matthew Greenleaf