Abstract: The invention relates to a peptide derived from an antigen recognized by autoantibodies, which peptide is reactive with autoimmune antibodies from a patient suffering from rheumatoid arthritis. The peptide according to the invention possesses a modified arginine residue. The invention also relates to antibodies against the peptide and a method of detecting autoimmune antibodies.

Abstract: The invention relates to a peptide derived from an antigen recognized by autoantibodies, which peptide is reactive with autoimmune antibodies from a patient suffering from rheumatoid arthritis. The peptide according to the invention possesses a modified arginine residue. The invention also relates to antibodies against the peptide and a method of detecting autoimmune antibodies.

Abstract: The invention concerns an inorganic scintillator material of general composition M1?xCexCl3, wherein: M is selected among lanthanides or lanthanide mixtures, preferably among the elements or mixtures of elements of the group consisting of Y, La, Gd, Lu, in particular among the elements or mixtures of elements of the group consisting of La, Gd and Lu; and x is the molar rate of substitution of M with cerium, x being not less than 1 mol % and strictly less than 100 mol %. The invention also concerns a method for growing said monocrystalline scintillator material, and the use of said scintillator material as component of a scintillating detector in particular for industrial and medical purposes and in the oil industry.

Abstract: The invention concerns an inorganic scintillator material of general composition M1-xCexBr3, wherein: M is selected among lanthanides or lanthanide mixtures of the group consisting of La, Gd, Y in particular among lanthanides or lanthanide mixtures of the group consisting of La, Gd; and x is the molar rate of substitution of M with cerium, x being not less that 0.01 mol % and strictly less than 100 mol %. The invention also concerns a method of growing such a monocrystalline scintillator material, and the use of same as component of a scintillating detector for industrial and medical purpose or in the oil industry.

Abstract: Fibre-reinforced material that substitutes for cartilage-like tissue, consisting of a hydrophilic, relatively elastic fibre structure and a matrix of polymerised hydrogel. The fibre/matrix bonding is increased by saturating the fibre in the monomer solution before polymerisation of the hydrogel. The fibre preferably consists of a material based on polyurethane. More particularly, this material contains 10-70% (m/m) fibres (based on the dry matter) and 1-5% (m/m) (based on the dry matter) of a substance that contains ionised groups has been added to said hydrogel.

Abstract: The invention concerns an inorganic scintillator material of general composition M1-xCexCl3, wherein: M is selected among lanthanides or lanthanide mixtures, preferably among the elements or mixtures of elements of the group consisting of Y, La, Gd, Lu, in particular among the elements or mixtures of elements of the group consisting of La, Gd and Lu; and x is the molar rate of substitution of M with cerium, x being not less than 1 mol % and strictly less than 100 mol %. The invention also concerns a method for growing said monocrystalline scintillator material, and the use of said scintillator material as component of a scintillating detector in particular for industrial and medical purposes and in the oil industry.

Abstract: The invention relates to an inorganic rare-earth iodide scintillation material of formula AXLn(y?y?,)Ln?y?I(x+3y) in which: A represents at least one element selected among Li, Na, K, Rb, Cs; Ln represents at least one first rare-earth element selected among La, Gd, Y, Lu, said first rare-earth element having a valency of 3+ in the aforementioned formula: Ln? represents at least one second rare-earth element selected among Ce, Tb, Pr, said second rare-earth element having a valency of 3+ in the aforementioned formula, x is an integer and represents 0, 1, 2 or 3; y is an integer or non-integer greater than 0 and less than 3, and; y? is an integer or non-integer greater than 0 and less than y. This material presents a high stopping power, a rapid decay time, in particular, less than 100 ns, a good energy resolution (in particular, less than 6% at 662 keV) and a high luminous level.

Abstract: The invention relates to a new class of isolated, single or multiple mutated glutaryl amidases from Pseudomonas SY-77, or a functional part, derivative or analogue thereof. The invention also relates to a method for preparing 7-aminocephalosporanic acid from cephalosporin C, using a glutaryl amidase according to the invention. The invention also provides a method for preparing aminodesacetoxycephalosporanic acid.

Abstract: A method of forming a diamond coating on an iron-based substrate, comprising: providing an iron based substrate with an outer layer which substantially comprises metal borides; and depositing the diamond coating on the outer layer using a process of Chemical Vapor Deposition (CVD). An outer layer may be formed by deposition, by depositing a metal layer which is capable of being boronized followed by boronizing the metal layer, or by boronizing the iron-based substrate. The invention is also related to the use of an iron-based substrate comprising an outer layer with borides for hosting a CVD diamond coating.

Abstract: The invention concerns an inorganic scintillator material of general composition M1-xCexCl3, wherein: M is selected among lanthanides or lanthanide mixtures, preferably among the elements or mixtures of elements of the group consisting of Y, La, Gd, Lu, in particular among the elements or mixtures of elements of the group consisting of La, Gd and Lu; and x is the molar rate of substitution of M with cerium, x being not less than 1 mol % and strictly less than 100 mol %. The invention also concerns a method for growing said monocrystalline scintillator material, and the use of said scintillator material as component of a scintillating detector in particular for industrial and medical purposes and in the oil industry.

Abstract: The invention concerns an inorganic scintillator material of general composition M1-xCexBr3, wherein: M is selected among lanthanides or lanthanide mixtures of the group consisting of La, Gd, Y in particular among lanthanides or lanthanide mixtures of the group consisting of La, Gd; and x is the molar rate of substitution of M with cerium, x being not less that 0.01 mol % and strictly less than 100 mol %. The invention also concerns a method of growing such a monocrystalline scintillator material, and the use of same as component of a scintillating detector for industrial and medical purpose or in the oil industry.

Abstract: A material that can be used for magnetic refrigeration, wherein the material substantially has the general formula (AYB1?y)2+?C1?xDx) wherein A is selected from Mn and Co; B is selected from Fe and Cr; C and D are different and are selected from P, As, B, Se, Ge, Si and Sb; x and y each is a number in the range 0–1; and ? is a number from (?0.1)–(+0.1).

Abstract: The invention concerns an inorganic scintillator material of general composition M1-xCexBr3, wherein: M is selected among lanthanides or lanthanide mixtures of the group consisting of La, Gd, Y in particular among lanthanides or lanthanide mixtures of the group consisting of La, Gd; and x is the molar rate of substitution of M with cerium, x being not less that 0.01 mol % and strictly less than 100 mol %. The invention also concerns a method of growing such a monocrystalline scintillator material, and the use of same as component of a scintillating detector for industrial and medical purpose or in the oil industry.

Abstract: An inorganic scintillator material, a method for growing the monocrystalline scintillator material, and the use of the scintillator material as component of a scintillating detector in particular for industrial and medical purposes and in the oil industry. The inorganic scintillator material has the general composition M1?xCexCl3, wherein: M is selected among lanthanides or lanthanide mixtures, preferably among the elements or mixtures of elements of the group consisting of Y, La, Gd, Lu, in particular among the elements or mixtures of elements of the group consisting of La, Gd and Lu; and x is the molar rate of substitution of M with cerium, x being not less than 1 mol % and strictly less than 100 mol %.

Abstract: Hearing aid for improving the hearing ability of the hard of hearing, comprising an array of microphones, the electrical output signals of which are fed to at least one transmission path belonging to an ear. Means are provided for deriving two array output signals from the output signals of the microphones, the array having two main sensitivity directions running at an angle with respect to one another and each of which is associated to an array output signal. Each array output signal is fed to its own transmission path belonging to one ear of a person who is hard of hearing.

Abstract: A compound includes a carrier molecule wherein the carrier molecule is linked to a further molecule, wherein the further molecule is at least one cyclic peptide in which the cyclic peptide portion thereof contains at least one sequence encoding a cell receptor recognizing peptide (RRP) and with the proviso that the compound is not a naturally occurring receptor agonist or antagonist. Preferably, the RRP is a receptor specific for Hepatic Stellate Cells (HSC) or a receptor that is up-regulated on HSC during disease. The RFP may be chosen from among a PDGF receptor, a collagen type VI receptor, cytokine receptor(s) such as TGB?, INF? and interleukin?. The cyclic portion of the peptide can contain at least one amino acid sequence RGD or KPT.

Abstract: The invention relates to a probe for a magnetic force microscope, comprising a movable cantilever placed in the plane of a wafer and a tip placed substantially at right angles to the cantilever, wherein the cantilever is able to move and its oscillation direction is in the wafer plane, and the tip lies virtually in or parallel to this wafer plane.

Abstract: Ultrasound imaging of tissue in medical applications is carried out by transmitting ultrasound energy into a target volume at least a first fundamental frequency, receiving reflected and/or scattered ultrasound energy from the target volume; and detecting components of the received signal at multiple harmonics of the fundamental frequency or at one or more of the third to fifth harmonics of the fundamental frequency. A image of the target volume is generated using the detected harmonic components of the received signal.

Abstract: The invention relates to a peptide derived from an antigen recognized by autoantibodies, which peptide is reactive with autoimmune antibodies from a patient suffering from rheumatoid arthritis. The peptide according to the invention possesses a modified arginine residue. The invention also relates to antibodies against the peptide and a method of detection autoimmune antibodies.

Abstract: The present invention relates to a compound comprising a carrier molecule, said carrier molecule being linked to a further molecule, said further molecule being at least one cyclic peptide, said cyclic peptide comprising in the cyclic peptide portion thereof at least one sequence encoding a cell receptor recognising peptide (RRP) and with the proviso that the compound is not a naturally occuring receptor agonist or antagonist. Preferably, the RRP is of a receptor specific for Hepatic Stellate Cells (HSC) or a receptor that is upregulated on HSC during disease. In particular, the RRP may be of a receptor selected from the group of PDGF receptor, collagen type VI receptor, cytokine receptor(s) such as TGF?, IFN? and interleukin 1?. Preferably, the cyclic portion of the cyclic peptide comprises at least the amino acid sequence RGD or KPT.