Abstract: A dermal patch to be worn on the skin for increasing the concentration of an analyte expressed through the skin in perspiration to a conveniently measurable level. Included are patches and methods of using such patches to determine the quantity of an analyte in a given volume of perspiration, to determine a subject's sensitivity to an allergen, to allow an analyte to be detected with conventional detection systems, and to dissolve the structural components of a patch to facilitate analyte detection.
Abstract: A non-occlusive dermal patch for collecting vapor phase perspiration from a subject's skin and retaining an analyte such as ethanol in the perspiration is disclosed. A method of collecting vapor phase perspiration containing an analyte such as ethanol over a period up to several days and detecting the analyte to determine the wearer's consumption of the analyte during the period when the patch was worn is disclosed.
Type:
Grant
Filed:
November 12, 1996
Date of Patent:
May 4, 1999
Assignee:
Sudormed, Inc.
Inventors:
Donald W. Schoendorfer, William R. Miller
Abstract: A dermal patch to be worn on the skin for increasing the concentration of an analyte expressed through the skin in perspiration to a conveniently measurable level. Included are patches and methods of using such patches to determine the quantity of an analyte in a given volume of perspiration, to determine a subject's sensitivity to an allergen, to allow an analyte to be detected with conventional detection systems, and to dissolve the structural components of a patch to facilitate analyte detection.
Abstract: A membrane (250) comprising an adhesive is secured to the skin (12) of a subject. The membrane (250) retains concentrated analyte in or on the membrane (250) itself, in the adhesive, and in the desquamated keratinized stratum corneum cells of the skin (12).
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