Abstract: A chromatographic method used to detect chronic alcohol usage and alcoholism and to monitor alcohol rehabilitation treatment; the method provides improved resolution of the Hb A.sub.1-AcH peak from the contiguous Hb A.sub.1c peak by means of a polyaspartic acid chromatographic column and a nonlinear buffer gradient; the resulting Hb A.sub.1-AcH peak is then evaluated to determine chronic alcohol usage which is indicative of alcoholism and which can be used to monitor alcohol rehabilitation treatment.
Type:
Grant
Filed:
May 18, 1993
Date of Patent:
October 24, 1995
Assignee:
Summa Health System
Inventors:
Edward B. Truitt, Jr., Susan E. Hazelett, Robert A. Liebelt