Abstract: A sterile pharmaceutical dosage form which comprises an ester capped lactide polymer, glycolide polymer or a lactide-glycolide copolymer hypercompressed with an active pharmaceutical ingredient wherein said sterile pharmaceutical dosage form has been sterilized with an electron beam and a method of preparing said sterile pharmaceutical dosage form.
Type:
Grant
Filed:
November 19, 2019
Date of Patent:
August 18, 2020
Assignee:
SUSTAINED NANO SYSTEMS LLC
Inventors:
Barry M. Libin, Jeffrey M. Liebmann, Weiliam Chen
Abstract: A sterile pharmaceutical dosage form which comprises an ester capped lactide polymer, glycolide polymer or a lactide-glycolide copolymer hypercompressed with an active pharmaceutical ingredient wherein said sterile pharmaceutical dosage form has been sterilized with an electron beam and a method of preparing said sterile pharmaceutical dosage form.
Type:
Grant
Filed:
July 10, 2018
Date of Patent:
December 10, 2019
Assignee:
SUSTAINED NANO SYSTEMS LLC
Inventors:
Barry M. Libin, Jeffrey M. Liebmann, Weiliam Chen
Abstract: A pharmaceutical dosage form which comprises a lactide, glycolide or lactide-glycolide polymer, a block polymer of polyglycolide, trimethylene carbonate, poly-caprolactone, and polyethylene oxide that is combined with a peptide or protein therapeutic agent in the form of microparticles which are compressed using a pressure of 50,000 to 350,000 psi.
Type:
Grant
Filed:
July 10, 2018
Date of Patent:
September 10, 2019
Assignee:
SUSTAINED NANO SYSTEMS LLC
Inventors:
Barry M. Libin, Jeffrey M. Liebmann, Weiliam Chen
Abstract: A dispensing device having a polymer which is combined with a therapeutic agent in the form of a microparticle or nanoparticle which is “hyper-compressed” to form a controlled release dispensing device and methods of locally administering a therapeutic agent using said microparticles.
Type:
Grant
Filed:
April 23, 2009
Date of Patent:
December 6, 2011
Assignee:
Sustained Nano Systems LLC
Inventors:
Barry M. Libin, Jeffrey M. Liebmann, Weiliam Chen
Abstract: A dispensing device having a polymer which is combined with a therapeutic agent in the form of a microparticle or nanoparticle which is “hyper-compressed” to form a controlled release dispensing device and methods of locally administering a therapeutic agent using said microparticles.
Type:
Application
Filed:
November 25, 2009
Publication date:
July 8, 2010
Applicant:
SUSTAINED NANO SYSTEMS LLC
Inventors:
Barry M. Libin, Jeffrey M. Liebmann, Weiliam Chen
Abstract: A dispensing device having a polymer which is combined with a therapeutic agent in the form of a microparticle or nanoparticle which is “hyper-compressed” to form a controlled release dispensing device and methods of locally administering a therapeutic agent using said microparticles.
Type:
Application
Filed:
April 23, 2009
Publication date:
October 29, 2009
Applicant:
SUSTAINED NANO SYSTEMS LLC
Inventors:
Barry M. Libin, Jeffrey M. Liebmann, Weiliam Chen
Abstract: A dispensing device having a polymer which is combined with a therapeutic agent in the form of a microparticle which is compressed to form a controlled release dispensing device and methods of locally administering a therapeutic agent using said microparticles.
Type:
Application
Filed:
November 13, 2008
Publication date:
June 11, 2009
Applicant:
SUSTAINED NANO SYSTEMS LLC
Inventors:
Barry M. Libin, Jeffrey M. Liebmann, Weiliam Chen
Abstract: An ophthalmic dispensing device having a polymer which is combined with an ophthalmic therapeutic agent in the form of a microparticle which is hypercompressed to form a controlled release dispensing device for ophthalmic use.
Type:
Application
Filed:
May 14, 2008
Publication date:
November 27, 2008
Applicant:
SUSTAINED NANO SYSTEMS LLC
Inventors:
Barry M. Libin, Jeffrey M. Liebmann, Weiliam Chen