Patents Assigned to Swiss Tropical and Public Health Institute
  • Proline-rich peptides protective against
    Patent number: 9943583
    Abstract: The invention relates to lipopeptides consisting of a peptide chain comprising a parallel coiled-coil domain, a proline-rich peptide antigen, and a lipid moiety, all covalently linked, which aggregate to synthetic virus-like particles. Proline-rich peptide antigens considered contain negatively and positively charged amino acid, and at least 15% of the amino acids are proline. Such synthetic virus-like particles carrying proline-rich antigens derived from pneumococcal proteins are useful as vaccines against infectious diseases caused by Gram-positive bacteria such as Streptococcus pneumoniae.
    Type: Grant
    Filed: December 2, 2014
    Date of Patent: April 17, 2018
    Assignees: UNIVERSITÄT ZÜRICH, SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE, VIROMETIX AG
    Inventors: Arin Ghasparian, Armando Zuniga, Nina Geib, Marco Tamborini, Maja Jud, Gerd Pluschke, Aniebrys Marrero Nodarse, John Anthony Robinson
  • Medicinal composition containing benzo[a]phenoxazine compound as the active ingredient for prevention or treatment of protozoal disease
    Patent number: 8288374
    Abstract: Provided is a medicinal composition, in particular, a medicinal composition for treatment and/or prevention which has a high therapeutic effect on infection with a parasitic protozoa and a selective toxicity thereto and exhibits a life-prolonging effect and so on. A medicinal composition which contains as the active ingredient a benzo[a]phenoxazine compound represented by General formula (1) or a salt compound of the same, in particular, an agent for treating and/or preventing infection with a protozoa such as malaria, leishmaniasis, African trypanosomiasis, Chagas disease, toxoplasmosis, lymphatic filariasis, babesiosis or coccidium disease; and a novel compound which is contained therein as the active ingredient.
    Type: Grant
    Filed: March 11, 2009
    Date of Patent: October 16, 2012
    Assignees: Hoshi University, Synstar Japan Co., Ltd., Swiss Tropical and Public Health Institute, FUJIFILM Corporation
    Inventors: Masataka Ihara, Jian-Feng Ge, Chika Arai, Nasser Saad Mohamed Ismail, Mei Yang, Isamu Itoh, Reto Brun
  • MEDICINAL COMPOSITION CONTAINING BENZO[A]PHENOXAZINE COMPOUND AS THE ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF PROTOZOAL DISEASE
    Publication number: 20110021450
    Abstract: Provided is a medicinal composition, in particular, a medicinal composition for treatment and/or prevention which has a high therapeutic effect on infection with a parasitic protozoa and a selective toxicity thereto and exhibits a life-prolonging effect and so on. A medicinal composition which contains as the active ingredient a benzo[a]phenoxazine compound represented by General formula (1) or a salt compound of the same, in particular, an agent for treating and/or preventing infection with a protozoa such as malaria, leishmaniasis, African trypanosomiasis, Chagas disease, toxoplasmosis, lymphatic filariasis, babesiosis or coccidium disease; and a novel compound which is contained therein as the active ingredient.
    Type: Application
    Filed: March 11, 2009
    Publication date: January 27, 2011
    Applicants: HOSHI UNIVERSITY, SYNSTAR JAPAN CO., LTD., SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE
    Inventors: Masataka Ihara, Jian-Feng Ge, Chika Arai, Mei Yang, Isamu Itoh, Reto Brun
  • Test strip for medical or laboratory purposes
    Patent number: D982776
    Type: Grant
    Filed: November 10, 2021
    Date of Patent: April 4, 2023
    Assignee: Swiss Tropical and Public Health Institute (Swiss TPH)
    Inventors: Michèle Stöcklin, Raimund Erdmann, Stefan Stübinger, Valentin Thomas Mcshea, Samantha Paoletti, Fabio Cirillo, Daniel Richards, Frank Dieterle, Daniel H. Paris