Abstract: According to the present invention, treatment of prion protein related diseases, and in particular cancer tumours, is effected by providing to a subject in need thereof a therapeutically effective amount of an agent capable of modulating binding of a prion protein and/or a prion-like protein to a disease related GAG and/or HSPG.
Type:
Application
Filed:
January 17, 2014
Publication date:
October 16, 2014
Applicant:
Sylvan Pharmaceuticals Pty, Ltd.
Inventors:
John Fergus McEwan, David Cullis-Hill, Martin Lyndale Windsor
Abstract: The present invention provides a candidate compound that is suitable for use in methods of treating animals (preferably mammals) and in the preparation of a medicament, wherein the candidate compound down regulates Cathepsin K activity.
Abstract: The present invention provides a candidate compound that is suitable for use in methods of treating animals (preferably mammals) and in the preparation of a medicament, wherein the candidate compound down regulates Cathepsin K activity.
Type:
Grant
Filed:
December 8, 2008
Date of Patent:
October 23, 2012
Assignee:
Sylvan Pharmaceuticals Pty Ltd.
Inventors:
David Cullis-Hill, Robert Logan Hannon, Christopher Bond Little, Margaret Mary Smith
Abstract: The present invention provides a candidate compound that is suitable for use in methods of treating animals (preferably mammals) and in the preparation of a medicament, wherein the candidate compound down regulates Cathepsin K activity.
Type:
Application
Filed:
December 8, 2008
Publication date:
April 30, 2009
Applicant:
Sylvan Pharmaceuticals Pty. Ltd. CAN 102 641 332
Inventors:
David Cullis-Hill, Robert Logan Hannon, Christopher Bond Little, Margaret Mary Smith
Abstract: The present invention provides a candidate compound that is suitable for use in methods of treating animals (preferably mammals) and in the preparation of a medicament, wherein the candidate compound down regulates Cathepsin K activity.
Type:
Application
Filed:
September 27, 2006
Publication date:
March 27, 2008
Applicant:
Sylvan Pharmaceuticals Pty Ltd.
Inventors:
David Cullis-Hill, Robert Logan Hannon, Christopher Bond Little, Margaret Mary Smith