Patents Assigned to Symbiotec Genellschaft zur Erforschung auf dem Geibeit der Biotechnologie, MBH
  • Bis-met histones
    Patent number: 9796767
    Abstract: The present invention provides a nucleic acid molecule which encodes a polypeptide consisting of two methionine residues as the first and second N-terminal amino acid residues linked via a peptide bond to a mature eukaryotic histone. The present invention furthermore relates to a vector containing said nucleic acid molecule, a host transformed with said vector, polypeptides encoded by the nucleic acid molecule and pharmaceutical and diagnostic compositions. The present invention also relates to the use of the nucleic acid molecule, vectors, hosts and the polypeptide of the invention for the preparation of a composition for the treatment of diseases. Furthermore, the present invention relates to a method of testing for the presence of the nucleic acid molecule or the polypeptide in a sample and to a kit.
    Type: Grant
    Filed: January 19, 2016
    Date of Patent: October 24, 2017
    Assignee: Symbiotec Genellschaft zur Erforschung auf dem Geibeit der Biotechnologie, MBH
    Inventors: Peter Gross, Hans Jornvall, Grazyna Formicka-Zeppezauer, Michael Zeppezauer, Michel Thiry
  • Bis-Met histones
    Patent number: 9790259
    Abstract: The present invention provides a nucleic acid molecule which encodes a polypeptide consisting of two methionine residues as the first and second N-terminal amino acid residues linked via a peptide bond to a mature eukaryotic histone. The present invention furthermore relates to a vector containing said nucleic acid molecule, a host transformed with said vector, polypeptides encoded by the nucleic acid molecule and pharmaceutical and diagnostic compositions. The present invention also relates to the use of the nucleic acid molecule, vectors, hosts and the polypeptide of the invention for the preparation of a composition for the treatment of diseases. Furthermore, the present invention relates to a method of testing for the presence of the nucleic acid molecule or the polypeptide in a sample and to a kit.
    Type: Grant
    Filed: January 19, 2016
    Date of Patent: October 17, 2017
    Assignee: Symbiotec Genellschaft zur Erforschung auf dem Geibeit der Biotechnologie, MBH
    Inventors: Peter Gross, Hans Jornvall, Grazyna Formicka-Zeppezauer, Michael Zeppezauer, Michel Thiry
  • Bis-Met Histones
    Publication number: 20160130313
    Abstract: The present invention provides a nucleic acid molecule which encodes a polypeptide consisting of two methionine residues as the first and second N-terminal amino acid residues linked via a peptide bond to a mature eukaryotic histone. The present invention furthermore relates to a vector containing said nucleic acid molecule, a host transformed with said vector, polypeptides encoded by the nucleic acid molecule and pharmaceutical and diagnostic compositions. The present invention also relates to the use of the nucleic acid molecule, vectors, hosts and the polypeptide of the invention for the preparation of a composition for the treatment of diseases. Furthermore, the present invention relates to a method of testing for the presence of the nucleic acid molecule or the polypeptide in a sample and to a kit.
    Type: Application
    Filed: January 19, 2016
    Publication date: May 12, 2016
    Applicant: Symbiotec Genellschaft zur Erforschung auf dem Geibeit der Biotechnologie, MBH
    Inventors: PETER GROSS, HANS JORNVALL, GRAZYNA FORMICKA-ZEPPEZAUER, MICHAEL ZEPPEZAUER, MICHEL THIRY
  • Bis-Met Histones
    Publication number: 20160130312
    Abstract: The present invention provides a nucleic acid molecule which encodes a polypeptide consisting of two methionine residues as the first and second N-terminal amino acid residues linked via a peptide bond to a mature eukaryotic histone. The present invention furthermore relates to a vector containing said nucleic acid molecule, a host transformed with said vector, polypeptides encoded by the nucleic acid molecule and pharmaceutical and diagnostic compositions. The present invention also relates to the use of the nucleic acid molecule, vectors, hosts and the polypeptide of the invention for the preparation of a composition for the treatment of diseases. Furthermore, the present invention relates to a method of testing for the presence of the nucleic acid molecule or the polypeptide in a sample and to a kit.
    Type: Application
    Filed: January 19, 2016
    Publication date: May 12, 2016
    Applicant: Symbiotec Genellschaft zur Erforschung auf dem Geibeit der Biotechnologie, MBH
    Inventors: Peter Gross, Hans Jornvall, Grazyna Formicka-Zeppezauer, Michael Zeppezauer, Michel Thiry