Patents Assigned to Synthetech, Inc.
  • Patent number: 5130252
    Abstract: A method for resolving racemic mixtures of compounds having the formula ##STR1## or a pharmaceutically acceptable salt thereof that includes the steps of reacting the OR.sub.3 group of either compound with an esterifying agent in the case where R.sub.3 is H or a lower alkyl group; sujecting the compound to the action of an esterase capable of preferentially hydrolyzing either the (+) or (-) enantiomeric form of the compound; and separating the unhydrolyzed compound from the hydrolyzed compound.
    Type: Grant
    Filed: May 14, 1990
    Date of Patent: July 14, 1992
    Assignee: Synthetech, Inc.
    Inventors: Charles R. Eck, Paul C. Ahrens, Rae M. Saltzstein
  • Patent number: 4935355
    Abstract: A process for forming a dipeptide which is substantially free of solid dipeptide-amino acid adduct by reacting the amino acid reactants in the presence of a polyol.
    Type: Grant
    Filed: April 15, 1986
    Date of Patent: June 19, 1990
    Assignee: Synthetech, Inc.
    Inventors: Duane C. Ulmer, Mary S. Rosendahl
  • Patent number: 4731469
    Abstract: This invention concerns a process for the recovery and purification of L-phenylalanine from a reaction mixture containing L-phenylalanine and contaminants.
    Type: Grant
    Filed: August 6, 1986
    Date of Patent: March 15, 1988
    Assignee: Synthetech, Inc.
    Inventors: David L. Evans, Roberta L. Thimmig, Robert C. Koltz