Patents Assigned to Syqe Medical Ltd.
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Publication number: 20240108577Abstract: This application relates to methods of delivering via inhalation from a source material both pharmacologically-effective doses and placebo dosesType: ApplicationFiled: October 11, 2023Publication date: April 4, 2024Applicant: Syqe Medical Ltd.Inventors: Ilana ZAKS BOHBOT, Joshua AVIRAM, Asaf KROLL, Anna FRENKLAKH, Roee LIFSHITZ, Daniella ATZMONY
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Publication number: 20240050397Abstract: Some embodiments of the invention relate to a system for delivering to a subject at least one pre-determined amount of THC, the system comprising: a memory which stores a scheduled regimen for delivery of THC to the subject, the scheduled regimen defining: a maximal amount of THC to be delivered, the amount being 0.75 mg THC or less, and a time period within which that amount is delivered, the time period being 2 hours or longer; a decision module which decides, according to the scheduled regimen, if a delivery should take place; and an inhaler device for delivering THC to the subject, the inhaler device comprising a controller which carries out delivery of THC based on the decision made by the decision module.Type: ApplicationFiled: October 12, 2023Publication date: February 15, 2024Applicant: Syqe Medical Ltd.Inventors: Perry DAVIDSON, Seth KINDLER, Shlomo ALMOG, Binyamin SCHWARTZ, Aaron SCHORR, Daniella ATZMONY
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Publication number: 20230390186Abstract: There is provided in accordance with an exemplary embodiment of the invention, a device and a method for controlled extraction of at least one active substance from at least one type of plant matter by application of heat, the device comprising: a heating element adapted to apply heat to an area of the plant matter to extract the substance; and a mechanism adapted for moving the plant matter relative to the heating element. Optionally, the active substance is a restricted substance. There is also provided in accordance with an exemplary embodiment of the invention, a method of monitoring and controlling inhalation of a restricted substance. There is provided in accordance with an exemplary embodiment of the invention, a method of manufacturing a tape of plant matter comprising an active substance.Type: ApplicationFiled: August 17, 2023Publication date: December 7, 2023Applicant: Syqe Medical Ltd.Inventors: Perry DAVIDSON, Aaron SCHORR, Arie HOLTZ, Will PONG, Binyamin SCHWARTZ
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Patent number: 11806331Abstract: Some embodiments of the invention relate to a system for delivering to a subject at least one pre-determined amount of THC, the system comprising: a memory which stores a scheduled regimen for delivery of THC to the subject, the scheduled regimen defining: a maximal amount of THC to be delivered, the amount being 0.75 mg THC or less, and a time period within which that amount is delivered, the time period being 2 hours or longer; a decision module which decides, according to the scheduled regimen, if a delivery should take place; and an inhaler device for delivering THC to the subject, the inhaler device comprising a controller which carries out delivery of THC based on the decision made by the decision module.Type: GrantFiled: January 5, 2017Date of Patent: November 7, 2023Assignee: Syqe Medical Ltd.Inventors: Perry Davidson, Seth Kindler, Shlomo Almog, Binyamin Schwartz, Aaron Schorr, Daniella Atzmony
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Patent number: 11766399Abstract: There is provided in accordance with an exemplary embodiment of the invention, a device and a method for controlled extraction of at least one active substance from at least one type of plant matter by application of heat, the device comprising: a heating element adapted to apply heat to an area of the plant matter to extract the substance; and a mechanism adapted for moving the plant matter relative to the heating element. Optionally, the active substance is a restricted substance. There is also provided in accordance with an exemplary embodiment of the invention, a method of monitoring and controlling inhalation of a restricted substance. There is provided in accordance with an exemplary embodiment of the invention, a method of manufacturing a tape of plant matter comprising an active substance.Type: GrantFiled: April 23, 2021Date of Patent: September 26, 2023Assignee: Syqe Medical Ltd.Inventors: Perry Davidson, Aaron Schorr, Arie Holtz, Will Pong, Binyamin Schwartz
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Publication number: 20230120935Abstract: A cavity authentication system for verifying at least one feature of a user using at least one acoustic signal, including an orifice element, including at least a signal opening and a reflection opening, an acoustic wave generator (AWG), an acoustic wave sensor (AWS), at least one output waveguide, at least one input waveguide, a processor, a memory and a power supply, the AWG for producing at least one acoustic signal, the AWS for receiving at least one reflection of the acoustic signal, the output waveguide for transmitting the acoustic signal to the user, the input waveguide for receiving the reflection of the acoustic signal, the memory configured to store cavity authentication data representative of the feature, wherein the processor is configured to analyze the reflection and to compare the analyzed reflection with the retrievable cavity authentication data and to generate an indication whether the analyzed reflection matches the retrievable cavity authentication data above a pre-determined threshold.Type: ApplicationFiled: September 14, 2021Publication date: April 20, 2023Applicant: Syqe Medical Ltd.Inventors: Perry DAVIDSON, Oren HAREL, Yakov Yury ROVNIAGIN, Harel GUR, Or AVERBUCH, Shay LANDA
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Publication number: 20220241523Abstract: An inhaler device for pulmonary delivery of at least one substance from a drug dose cartridge to an inhaling user, including: a first conduit for conducting a carrier airflow to a proximal opening of a mouthpiece for use by the user; a holder configured to position the dose cartridge within the carrier airflow; and a second conduit for conducting a shunting airflow to the mouthpiece without passing through the dose cartridge position. In some embodiments, a controller connected to a valve controls a rate of carrier airflow, for example by controlling the shunting airflow, based on a sensor indication of airflow rate and a target airflow profile.Type: ApplicationFiled: February 24, 2022Publication date: August 4, 2022Applicant: Syqe Medical Ltd.Inventors: Perry DAVIDSON, Aaron SCHORR, Binyamin SCHWARTZ
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Publication number: 20220223247Abstract: Some embodiments relate to a method for generating a delivery regimen of at least one active substance to a user, comprising: receiving input including one or both of timed activities to be engaged by the user, timed preferred user experiences; and automatically generating a delivery regimen including at least one of delivery times and amounts of the at least one active substance, based on: (a) estimating at least one of a timing and magnitude of at least one effect expected to be induced by the at least one active substance on the user; and (b) estimating an impact of the at least one effect on the timed activities and/or the timed preferred user experiences.Type: ApplicationFiled: May 21, 2020Publication date: July 14, 2022Applicant: Syqe Medical Ltd.Inventors: Perry DAVIDSON, Ianiv Yosef EISENSCHER, Yotam HOFFMANN
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Publication number: 20220211958Abstract: Provided herein is a method of pulmonary delivering to a subject at least one pharmacologically active agent being in a plant material, which is effected by pulmonary delivering the agent to the subject using a metered dose inhaler device that is configured to vaporize at least one pre-determined vaporized amount of the agent upon controllably heating the plant material, wherein the pre-determined vaporized amount is selected so as to achieve at least one pre-determined pharmacokinetic effect and/or at least one pre-determined pharmacodynamic effect induced by the agent in the subject.Type: ApplicationFiled: March 15, 2022Publication date: July 7, 2022Applicant: Syqe Medical Ltd.Inventors: Perry DAVIDSON, Shlomo ALMOG, Seth KINDLER
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Publication number: 20220183962Abstract: A dose unit including at least one isolated bioactive agent applied on a carrier material in thermal contact with an electrically heating element configured to vaporize a pre-determined amount of the agent for pulmonary delivery thereof is provided herein, as well as devices for effecting vaporization and pulmonary delivery of the isolated agent, and methods for preparing the dose unit, controllably releasing the agent therefrom, methods for pulmonary delivery thereof and methods of treatment of medical conditions treatable by pulmonary delivery of the isolated bioactive agent.Type: ApplicationFiled: March 2, 2022Publication date: June 16, 2022Applicant: Syqe Medical Ltd.Inventors: Perry Davidson, Aaron Schorr, Asaf Kroll, Binyamin Schwartz
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Publication number: 20220143338Abstract: According to some embodiments there is provided a device configured for releasing at least one substance from source material, comprising: a housing; a plurality of source material sections positioned at fixed locations with respect to the housing; a plurality of airflow paths, each airflow path associated with at least one source material section; each airflow path associated with at least one blocking element which prevents flow of air through the path; and an actuator operably coupled to the blocking element, the actuator configured for unblocking the airflow path of at least one selected source material section to allow flow of air to and through source material within the selected section.Type: ApplicationFiled: January 20, 2022Publication date: May 12, 2022Applicant: Syqe Medical Ltd.Inventors: Perry DAVIDSON, Binyamin SCHWARTZ, Aaron SCHORR, Nimrod RESHEF, Eran OREN, Be'eri KATZNELSON
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Patent number: 11311480Abstract: A dose unit including at least one isolated bioactive agent applied on a carrier material in thermal contact with an electrically heating element configured to vaporize a pre-determined amount of the agent for pulmonary delivery thereof is provided herein, as well as devices for effecting vaporization and pulmonary delivery of the isolated agent, and methods for preparing the dose unit, controllably releasing the agent therefrom, methods for pulmonary delivery thereof and methods of treatment of medical conditions treatable by pulmonary delivery of the isolated bioactive agent.Type: GrantFiled: August 6, 2018Date of Patent: April 26, 2022Assignee: Syqe Medical Ltd.Inventors: Perry Davidson, Aaron Schorr, Asaf Kroll, Binyamin Schwartz
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Patent number: 11298477Abstract: Provided herein is a method of pulmonary delivering to a subject at least one pharmacologically active agent being in a plant material, which is effected by pulmonary delivering the agent to the subject using a metered dose inhaler device that is configured to vaporize at least one pre-determined vaporized amount of the agent upon controllably heating the plant material, wherein the pre-determined vaporized amount is selected so as to achieve at least one pre-determined pharmacokinetic effect and/or at least one pre-determined pharmacodynamic effect induced by the agent in the subject.Type: GrantFiled: July 10, 2018Date of Patent: April 12, 2022Assignee: Syqe Medical Ltd.Inventors: Perry Davidson, Shlomo Almog, Seth Kindler
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Patent number: 11291781Abstract: An inhaler device for pulmonary delivery of at least one substance from a drug dose cartridge to an inhaling user, including: a first conduit for conducting a carrier airflow to a proximal opening of a mouthpiece for use by the user; a holder configured to position the dose cartridge within the carrier airflow; and a second conduit for conducting a shunting airflow to the mouthpiece without passing through the dose cartridge position. In some embodiments, a controller connected to a valve controls a rate of carrier airflow, for example by controlling the shunting airflow, based on a sensor indication of airflow rate and a target airflow profile.Type: GrantFiled: June 11, 2019Date of Patent: April 5, 2022Assignee: Syqe Medical Ltd.Inventors: Perry Davidson, Aaron Schorr, Binyamin Schwartz
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Publication number: 20220096760Abstract: Some embodiments relate to a method for heating for controlled release of at least one substance to be delivered to a user via inhalation, comprising: allowing airflow through a pallet of source material from which the at least one substance is releasable by vaporization; wherein airflow enters the pallet through a first surface and exits the pallet through a second, opposite surface of the pallet; heating a first heating element in contact with the first surface of the pallet according to a first temperature profile; and heating a second heating element in contact with the second surface of the pallet according to a second temperature profile which is different than the first temperature profile.Type: ApplicationFiled: February 6, 2020Publication date: March 31, 2022Applicant: Syqe Medical Ltd.Inventors: Binyamin SCHWARTZ, Nimrod RESHEF, Aaron SCHORR, Tal LUPO
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Publication number: 20220031972Abstract: Devices and methods are described for preparing, managing, and/or administering metered doses of substances for vaporized administration. In some embodiments, dose cartridges comprising at least one botanical substance include a heating element integrated into the cartridge in close contact with the botanical substance. In some embodiments, cartridge-mounted doses are stored in a magazine, optionally in carousel form, before use. Transport of a cartridge from a magazine to an electrically operated vaporizing chamber which activates the heating element is provided by a mechanical pickup means.Type: ApplicationFiled: October 19, 2021Publication date: February 3, 2022Applicant: Syqe Medical Ltd.Inventors: Perry DAVIDSON, Aaron SCHORR, Binyamin SCHWARTZ, Roee LIFSHITZ, Shay LANDA
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Patent number: 11229758Abstract: According to some embodiments there is provided a device configured for releasing at least one substance from source material, comprising: a housing; a plurality of source material sections positioned at fixed locations with respect to the housing; a plurality of airflow paths, each airflow path associated with at least one source material section; each airflow path associated with at least one blocking element which prevents flow of air through the path; and an actuator operably coupled to the blocking element, the actuator configured for unblocking the airflow path of at least one selected source material section to allow flow of air to and through source material within the selected section.Type: GrantFiled: January 11, 2017Date of Patent: January 25, 2022Assignee: Syqe Medical Ltd.Inventors: Perry Davidson, Binyamin Schwartz, Aaron Schorr, Nimrod Reshef, Eran Oren, Be'eri Katznelson
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Publication number: 20210402109Abstract: Some embodiments relate to a cartridge for use with an inhaler, the cartridge comprising: a plurality of source material units and a unit coupler configured for selectively interlocking to each of the source material units so that when the cartridge is operably attached to the inhaler, manipulation of the unit coupler moves the interlocked source material unit away from or back into the cartridge; the unit coupler and each of the source material units being formed with an interlocking geometry in which a protrusion of one fits within a respective recess of the other.Type: ApplicationFiled: October 28, 2019Publication date: December 30, 2021Applicant: Syqe Medical Ltd.Inventors: Shay LANDA, Roee LIFSHITZ, Abraham MEYER, Binyamin SCHWARTZ, Harel GUR
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Patent number: 11160937Abstract: Devices and methods are described for preparing, managing, and/or administering metered doses of substances for vaporized administration. In some embodiments, dose cartridges comprising at least one botanical substance include a heating element integrated into the cartridge in close contact with the botanical substance. In some embodiments, cartridge-mounted doses are stored in a magazine, optionally in carousel form, before use. Transport of a cartridge from a magazine to an electrically operated vaporizing chamber which activates the heating element is provided by a mechanical pickup means.Type: GrantFiled: September 14, 2018Date of Patent: November 2, 2021Assignee: Syqe Medical Ltd.Inventors: Perry Davidson, Aaron Schorr, Binyamin Schwartz, Roee Lifshitz, Shay Landa
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Publication number: 20210236414Abstract: There is provided in accordance with an exemplary embodiment of the invention, a device and a method for controlled extraction of at least one active substance from at least one type of plant matter by application of heat, the device comprising: a heating element adapted to apply heat to an area of the plant matter to extract the substance; and a mechanism adapted for moving the plant matter relative to the heating element. Optionally, the active substance is a restricted substance. There is also provided in accordance with an exemplary embodiment of the invention, a method of monitoring and controlling inhalation of a restricted substance. There is provided in accordance with an exemplary embodiment of the invention, a method of manufacturing a tape of plant matter comprising an active substance.Type: ApplicationFiled: April 23, 2021Publication date: August 5, 2021Applicant: Syqe Medical Ltd.Inventors: Perry DAVIDSON, Aaron SCHORR, Arie HOLTZ, Will PONG, Binyamin SCHWARTZ