Patents Assigned to System Instruments Co., Ltd.
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Patent number: 11987643Abstract: A monoclonal antibody or an antibody fragment thereof is provided, in which the monoclonal antibody or the antibody fragment thereof specifically binds to a sugar chain in which a terminal sialic acid residue is bonded to galactose by an ?2,3 bond, and is not dissociated from the sugar chain after the binding to the sugar chain in which the terminal sialic acid residue is bonded to the galactose by the ?2,3 bond.Type: GrantFiled: March 18, 2021Date of Patent: May 21, 2024Assignees: Hirosaki University, System Instruments Co. , Ltd.Inventors: Chikara Ohyama, Tohru Yoneyama, Kazuyuki Hamada
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Patent number: 10786778Abstract: A power supply control device of a nitrogen gas generator includes: a pipe having a nitrogen gas inlet for receiving input of nitrogen gas from a nitrogen gas generator that compresses air by a compressor to separate the nitrogen gas from the air, and a nitrogen gas outlet for outputting, to outside, the nitrogen gas received by the nitrogen gas inlet; a pressure gauge that measures pressure inside the pipe; a flowmeter that measures a flow rate of the nitrogen gas flowing inside the pipe; and a control unit that controls supply of power to the compressor and shut-off of the supply of the power in accordance with a measurement result of at least one of the pressure gauge and the flowmeter.Type: GrantFiled: January 15, 2016Date of Patent: September 29, 2020Assignee: SYSTEM INSTRUMENTS CO., LTD.Inventors: Kiyoshi Yamamoto, Yoshihisa Ujima, Takeshi Akiba
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Patent number: 10471011Abstract: Provided is a molecular imprint polymer that is capable of acquiring stealth properties through a new mechanism. The molecular imprint polymer according to the present invention, which has a plasma protein recognition sites molecularly imprinted by a plasma protein thereon and contains a constituent derived from a biocompatible monomer, is an in vivo stealth nanoparticle to be used in intravascular delivery. As the plasma protein, albumin is preferred. When carrying a drug thereon, the in vivo stealth nanoparticle according to the present invention is usable as a drug for drug delivery system.Type: GrantFiled: December 4, 2015Date of Patent: November 12, 2019Assignees: System Instruments Co., Ltd.Inventors: Toshifumi Takeuchi, Yukiya Kitayama
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Patent number: 10302638Abstract: An automatic analyzing apparatus 10 includes a chip rack 11 that stores a pipette chip, a pipette 12 into which a specimen is injected, a conveyance unit that conveys the pipette 12 by parallel translation, a reagent rack 14, a reaction unit 15, a detection unit 16, and a detection block unit 17. The pipette chip stored by the chip rack 11 has a planar structure to directly and optically detect the specimen. The chip rack 11 includes, in a hole that receives the pipette chip, a guide corresponding to the structure of the pipette chip. The pipette 12 sucks or discharges the specimen via the pipette chip mounted onto the tip thereof by a drive of a pump. In the detection unit 16, a measurement is carried out with the pipette chip arranged so that the plane that receives light is vertical to an optical axis.Type: GrantFiled: May 19, 2014Date of Patent: May 28, 2019Assignees: SYSTEM INSTRUMENTS CO., LTD., HIROSAKI UNIVERSITY, NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITYInventors: Kazuyuki Hamada, Takeshi Akiba, Chikara Ohyama, Tohru Yoneyama, Yuki Tobisawa, Toshifumi Takeuchi
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Patent number: 10258794Abstract: Provided is an electrical stimulation device including a first to fourth electrodes, and an electrical stimulation generation section which supplies an electrical stimulation signal to each of the first to fourth electrodes. The electrical stimulation generation section supplies, to the first and second electrodes, an electrical stimulation signal according to a first stimulation pattern, and supplies, to the third and fourth electrodes, an electrical stimulation signal according to a second stimulation pattern. The first stimulation pattern is set so that an electrical stimulation signal for changing stimulation intensity according to a first waveform is supplied to the first electrode, and an electrical stimulation signal for changing stimulation intensity according to a second waveform is supplied to the second electrode, the second waveform being increased and decreased in conjunction with the first waveform.Type: GrantFiled: July 23, 2014Date of Patent: April 16, 2019Assignees: SYSTEM INSTRUMENTS CO., LTD., THE UNIVERSITY OF ELECTRO-COMMUNICATIONSInventors: Takeshi Akiba, Hiroshi Yokoi
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Publication number: 20180353897Abstract: A power supply control device of a nitrogen gas generator includes: a pipe having a nitrogen gas inlet for receiving input of nitrogen gas from a nitrogen gas generator that compresses air by a compressor to separate the nitrogen gas from the air, and a nitrogen gas outlet for outputting, to outside, the nitrogen gas received by the nitrogen gas inlet; a pressure gauge that measures pressure inside the pipe; a flowmeter that measures a flow rate of the nitrogen gas flowing inside the pipe; and a control unit that controls supply of power to the compressor and shut-off of the supply of the power in accordance with a measurement result of at least one of the pressure gauge and the flowmeter.Type: ApplicationFiled: January 15, 2016Publication date: December 13, 2018Applicant: SYSTEM INSTRUMENTS CO., LTD.Inventors: Kiyoshi YAMAMOTO, Yoshihisa UJIMA, Takeshi AKIBA
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Patent number: 9952606Abstract: In an embodiment, control is performed to operate a three-way valve in accordance with a reaching ratio of pH adjustment. When process of certain steps is performed, bubbles of ammonia generated in a nebulizer can be extruded by air so as to be injected from an injection port together with aqua ammonia remaining in the nebulizer. Therefore, the pH adjustment can be performed while a large amount of bubbles of ammonia are prevented from being generated in the nebulizer.Type: GrantFiled: July 15, 2014Date of Patent: April 24, 2018Assignees: SYSTEM INSTRUMENTS CO., LTD., NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Toshiharu Kuroda, Michio Horiuchi, Yanbei Zhu, Koichi Chiba
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Patent number: 9754158Abstract: A training device includes an information outputter, an exercise status detector, an arithmetic processor, and a stimulus signal generator. The information outputter includes at least one of an image output unit and an audio output unit. The exercise status detector includes a body portion, a first grip portion and a second grip portion provided on the body portion, and sensors that detect a motion of the body portion. The arithmetic processor issues training action instruction information through the information outputter, and evaluates a matching degree between the contents of the training action instruction information and the motion of the body portion, based on output signals from the sensors of the exercise status detector. The stimulus signal generator applies a stimulus signal to the arm of a trainee.Type: GrantFiled: September 6, 2012Date of Patent: September 5, 2017Assignee: SYSTEM INSTRUMENTS CO., LTD.Inventors: Kazuyuki Hamada, Takeshi Akiba, Junichi Hoshino
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Patent number: 9702850Abstract: To provide an electrophoresis method and an electrophoresis device which can reduce difficulty in operation while implementing sufficient staining. An electrophoresis device includes a temperature gradient tank, a dispenser, a holder storage cabinet, a photographing unit, a PCR device, a chip rack, a chip disposal box, a DC power unit, a control unit, an arm, and a liquid feeder. A holder and a cassette removably attached to the holder are put on the temperature gradient tank. The control unit controls a carrying device, the arm, the liquid feeder, the temperature gradient tank, an excitation light source and a camera in the photographing unit, and the DC power unit. The control unit prestores a program for executing the control operation in its internal memory.Type: GrantFiled: April 30, 2013Date of Patent: July 11, 2017Assignees: SYSTEM INSTRUMENTS CO., LTD., NIHON UNIVERSITYInventors: Yoshinori Hatakeyama, Yoshihisa Ujima, Nobuaki Shimura
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Publication number: 20170100586Abstract: Provided is an electrical stimulation device including a first to fourth electrodes, and an electrical stimulation generation section which supplies an electrical stimulation signal to each of the first to fourth electrodes. The electrical stimulation generation section supplies, to the first and second electrodes, an electrical stimulation signal according to a first stimulation pattern, and supplies, to the third and fourth electrodes, an electrical stimulation signal according to a second stimulation pattern. The first stimulation pattern is set so that an electrical stimulation signal for changing stimulation intensity according to a first waveform is supplied to the first electrode, and an electrical stimulation signal for changing stimulation intensity according to a second waveform is supplied to the second electrode, the second waveform being increased and decreased in conjunction with the first waveform.Type: ApplicationFiled: July 23, 2014Publication date: April 13, 2017Applicants: SYSTEM INSTRUMENTS CO., LTD., The University of Electro-CommunicationsInventors: Takeshi AKIBA, Hiroshi YOKOI
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Publication number: 20160195880Abstract: In an embodiment, control is performed to operate a three-way valve in accordance with a reaching ratio of pH adjustment. When process of certain steps is performed, bubbles of ammonia generated in a nebulizer can be extruded by air so as to be injected from an injection port together with aqua ammonia remaining in the nebulizer. Therefore, the pH adjustment can be performed while a large amount of bubbles of ammonia are prevented from being generated in the nebulizer.Type: ApplicationFiled: July 15, 2014Publication date: July 7, 2016Applicants: SYSTEM INSTRUMENTS CO., LTD., NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Toshiharu KURODA, Michio HORIUCHI, Yanbei ZHU, Koichi CHIBA
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Patent number: 9251718Abstract: The training apparatus includes a training machine, a detection means, and an arithmetic means. The training machine has a displacement unit displaced according to a training action and a load generation unit that imparts a load to a trainee. The detection means detects displacement of the displacement unit. The arithmetic means acquires at least one characteristic value possessed by a waveform corresponding to one unit of a training action which waveform is included in the displacement detected in the detection unit on a time axis, for each waveform, and to evaluate the acquired characteristic values for at least one of variation, transition tendency, and deviation from a predetermined value. The arithmetic means executes, based on the evaluation, at least one of control of the load generation unit, calculation of a load value set in the load generation unit, and notification of a result of the evaluation.Type: GrantFiled: April 11, 2012Date of Patent: February 2, 2016Assignee: SYSTEM INSTRUMENTS CO., LTD.Inventor: Takeshi Akiba
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Patent number: 8992384Abstract: A training apparatus includes a training machine, a detecting unit, a signal generating unit, and a control unit. The training machine includes a displaceable part that is movable in response to exercise motions performed by the exerciser during training exercise. The detecting unit detects the displacement of the displaceable part or detects the displacement of the target training area of the exerciser resulting from the exercise motions. The signal generating unit generates a stimulus signal to be applied to the exerciser during the training exercise. The control unit corrects a content of processing relating to stimulus signal performed by the signal generating unit based on the displacement detected by the detecting unit.Type: GrantFiled: June 6, 2011Date of Patent: March 31, 2015Assignee: System Instruments Co., LtdInventors: Kazuyuki Hamada, Takeshi Akiba, Hiroshi Yokoi
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Publication number: 20150081057Abstract: A training device includes an information outputter, an exercise status detector, an arithmetic processor, and a stimulus signal generator. The information outputter includes at least one of an image output unit and an audio output unit. The exercise status detector includes a body portion, a first grip portion and a second grip portion provided on the body portion, and sensors that detect a motion of the body portion. The arithmetic processor issues training action instruction information through the information outputter, and evaluates a matching degree between the contents of the training action instruction information and the motion of the body portion, based on output signals from the sensors of the exercise status detector. The stimulus signal generator applies a stimulus signal to the arm of a trainee.Type: ApplicationFiled: September 6, 2012Publication date: March 19, 2015Applicant: SYSTEM INSTRUMENTS CO., LTD.Inventors: Kazuyuki Hamada, Takeshi Akiba, Junichi Hoshino
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Publication number: 20140113261Abstract: The training apparatus includes a training machine, a detection means, and an arithmetic means. The training machine has a displacement unit displaced according to a training action and a load generation unit that imparts a load to a trainee. The detection means detects displacement of the displacement unit. The arithmetic means acquires at least one characteristic value possessed by a waveform corresponding to one unit of a training action which waveform is included in the displacement detected in the detection unit on a time axis, for each waveform, and to evaluate the acquired characteristic values for at least one of variation, transition tendency, and deviation from a predetermined value. The arithmetic means executes, based on the evaluation, at least one of control of the load generation unit, calculation of a load value set in the load generation unit, and notification of a result of the evaluation.Type: ApplicationFiled: April 11, 2012Publication date: April 24, 2014Applicant: SYSTEM INSTRUMENTS CO., LTD.Inventor: Takeshi Akiba
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Publication number: 20130137549Abstract: A training apparatus includes a training machine, a detecting unit, a signal generating unit, and a control unit. The training machine includes a displaceable part that is movable in response to exercise motions performed by the exerciser during training exercise. The detecting unit detects the displacement of the displaceable part or detects the displacement of the target training area of the exerciser resulting from the exercise motions. The signal generating unit generates a stimulus signal to be applied to the exerciser during the training exercise. The control unit corrects a content of processing relating to stimulus signal performed by the signal generating unit based on the displacement detected by the detecting unit.Type: ApplicationFiled: June 6, 2011Publication date: May 30, 2013Applicant: SYSTEM INSTRUMENTS CO., LTD.Inventors: Kazuyuki Hamada, Takeshi Akiba, Hiroshi Yokoi
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Publication number: 20110111443Abstract: To provide an autoanalyzer for analyzing a sugar chain contained in a biological sample, in particular, serum. Namely, it is intended to provide a method of analyzing a sugar chain in a sample, which comprises the following steps: A) the sugar chain-releasing step of releasing the sugar chain in the sample; B) the detection sample-preparing step of preparing the released sugar chain for detection; and, in the case of conducting mass spectrometry using a plate, C) the step of forming a plate for the mass spectrometry having the captured sugar chain dotted thereon which comprises the step of providing the tagged sugar chain sample solution obtained in the step B) on a collection plate; and, if required, the step of conducting an operation in a solid phase support-enclosed plate to form the plate for mass spectrometry; and D) the step of analyzing the sugar chain to be assayed.Type: ApplicationFiled: October 3, 2008Publication date: May 12, 2011Applicants: NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY, SYSTEM INSTRUMENTS CO., LTD., SHIONOGI & CO., LTD.Inventors: Shinichiro Nishimura, Yasuro Shinohara, Yoshiaki Miura, Hiroshi Yamazaki, Michio Horiuchi, Hiroaki Motoki, Toshiharu Kuroda, Yoko Kita, Mika Nakano
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Patent number: 7922621Abstract: In order to measure a physical exercise condition data at a time of pre-testing and a muscle force training to accumulate and indicate them together with various set data, a muscle force training machine having a training apparatus main body and a training load applying apparatus is provided with a rotation detecting sensor which detects a rotating direction and an amount of rotation of a main shaft within the training load applying apparatus, and a data processing apparatus which stores the rotating direction and the amount of rotation from the rotation detecting sensor together with set data at least including a load amount, various body condition information of a training person and other data necessary for measuring in a data base, and processes them to make indicative data in forms of display data, print data and the like.Type: GrantFiled: September 21, 2010Date of Patent: April 12, 2011Assignee: System Instruments Co., Ltd.Inventors: Kazuyuki Hamada, Yoshihisa Ujima, Tsutomu Nishizawa
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Publication number: 20110077128Abstract: In order to measure a physical exercise condition data at a time of pre-testing and a muscle force training to accumulate and indicate them together with various set data, a muscle force training machine having a training apparatus main body and a training load applying apparatus is provided with a rotation detecting sensor which detects a rotating direction and an amount of rotation of a main shaft within the training load applying apparatus, and a data processing apparatus which stores the rotating direction and the amount of rotation from the rotation detecting sensor together with set data at least including a load amount, various body condition information of a training person and other data necessary for measuring in a data base, and processes them to make indicative data in forms of display data, print data and the like.Type: ApplicationFiled: September 21, 2010Publication date: March 31, 2011Applicant: SYSTEM INSTRUMENTS CO., LTD.Inventors: Kazuyuki Hamada, Yoshihisa Ujima, Tsutomu Nishizawa
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Patent number: 7298485Abstract: The device for measuring an optical absorption characteristic of a sample according to the present invention comprising a light source, a optical wave-guide having light input surface(s) and light output surface(s) that are opposite to each other, and a light reflecting surface on which a sample to be measured is disposed, through which the light passes and is reflected by a total reflection on the sample, one or more light transmitting means arranged between the light output surface of the optical wave-guide and the light input surface of the optical wave-guide so that the light is again entered into the optical wave-guide, and a processing device which receives the light re-exited from the optical wave-guide through the output surface and detects the optical absorption characteristics of the sample on the basis of the light received, whereby the light which passes through the optical wave-guide is conducted to the optical wave-guide again, the light is again entered the optical wave-guide, and the light isType: GrantFiled: August 10, 2005Date of Patent: November 20, 2007Assignee: System Instruments Co., Ltd.Inventor: Hiromi Takahashi