Abstract: The present disclosure provides a method for synthesizing fibrous silica nanospheres, the method can include, in sequence, the steps of: a) providing a reaction mixture comprising a silica precursor, a hydrolyzing agent, a template molecule, a cosurfactant and one or more solvents; b) maintaining the reaction mixture under stirring for a length of time; c) heating the reaction mixture to a temperature for a length of time; d) cooling the reaction mixture to obtain a solid, and (e) calcinating the solid to pro duce fibrous silica nanospheres, wherein desirable product characteristics such as particle size, fiber density, surface area, pore volume and pore size can be obtained by controlling one or more parameters of the method. The present disclosure further provides a method for synthesizing fibrous silica nanospheres using conventional heating such as refluxing the reactants in an open reactor, thereby eliminating the need for microwave heating in a closed reactor or the need for any pressure reactors.

Abstract: Described herein are nucleic acid molecules and complexes useful as i-switch pH reporters that have increased sensitivities as a pH reporter and have alternate pH reporting capacity ranges. Aspects of the disclosure relate to a method for determining pH comprising providing a nucleic acid complex comprising: a first single-stranded nucleic acid molecule comprising the sequence CnXCnYCnZCn (SEQ ID NO.

Abstract: The present invention discloses a method for securing information flow in an information system. The method comprises intercepting access requests to information in the information system by all applications running in the information system, intuitively assigning labels to all the information and the applications depending on the application requirements, combining the application making the access request and the information for which the access request is made with their respective labels, checking allowance of the access request based on comparison of the label corresponding to the application making the access request and the label corresponding to the information for which the access request is made and accordingly providing access of the information to the application on detection of allowable access request else denying the access request.

Abstract: The invention provides targets coated with structured biological materials, which are employed in laser produced plasma systems. The biological materials selected from cells of microbial, protozoan or plankton origin are applied on a portion of a solid target, like polished glass plate which then form a target system that absorbs the intense laser pulses, generates hot dense plasma and results in the emission of the X-rays. The method of coating structured biomaterial decreases the usable laser intensity required for producing the hot plasma, while increasing the X-ray yield. The coatings are easy to prepare and it is possible to vary the nature and shape of the cellular material in order to control/regulate the interaction with the light and thereby optimize the resultant plasma generation and X-ray emission.

Abstract: This invention relates to a confocal fluorescence correlation microscope with real-time alignment read out. With this instrument it is possible to do confocal imaging together with the particle size determination at a chosen location in the specimen. In particular, this invention relates to a detector module with a fixed aperture and detection electronics that can be conveniently connected to an existing confocal or multiphoton microscope, near the base of the objective lens of the microscope. This detector splits a part of the signal and uses it to generate a spot on the confocal image. This shows the spot where an FCS measurement can be carried out, and the same signal can then be used to perform a fluorescence correlation measurement after parking the excitation beam of the confocal to that spot. No alignment step is necessary for obtaining the measurement.

Abstract: A novel assay method suitable for screening of novel antipsychotics wherein the drugs may be selected based on the differential internalization of the 5-HT2A receptor in neuronal and non-neuronal cell lines effect for it to predict the extrapyramidal symptoms that may be induced by an antipsychotic without having to carry out in vivo experiments.

Abstract: This invention relates to a confocal fluorescence correlation microscope with real-time alignment read out. With this instrument it is possible to do confocal imaging together with the particle size determination at a chosen location in the specimen. In particular, this invention relates to a detector module with a fixed aperture and detection electronics that can be conveniently connected to an existing confocal or multiphoton microscope, near the base of the objective lens of the microscope. This detector splits a part of the signal and uses it to generate a spot on the confocal image. This shows the spot where an FCS measurement can be carried out, and the same signal can then be used to perform a fluorescence correlation measurement after parking the excitation beam of the confocal to that spot. No alignment step is necessary for obtaining the measurement.

Abstract: A novel process for preparing chromium dioxide of substantially high purity as well as composites of CrO2/Cr2O3 and CrO2/Cr2O5 following a sequence of simple steps. The process does not require pressure as a control parameter during the process of synthesis. No chemical modifier has been used to bring down the working pressure during synthesis. Fairly hard sintered pellets of CrO2 can be obtained without introducing any detectable impurity phase that usually appears during the process of sintering. Further, CrO2/Cr2O3 and CrO2/Cr2O5 composites have also been prepared where the fraction of insulating Cr2O3 or Cr2O5 in metallic CrO2 can be easily controlled. Significant negative magnetoresistance is found in pure CrO2 (5% MR) as well as CrO2/Cr2O3 (33% MR) composites near room temperature. The MR studies on the CrO2/Cr2O5 composites have been done and significant negative MR (22%) has been found in CrO2/Cr2O5 composites near room temperature.

Abstract: A novel assay method suitable for screening of novel antipsychotics wherein the drugs may be selected based on the differential internalization of the 5-HT2A receptor in neuronal and non-neuronal cell lines effect for it to predict the extrapyramidal symptoms that may be induced by an antipsychotic without having to carry out in vivo experiments.

Abstract: The back-up structure of a parabolic dish antenna, which supports its reflecting surface, is formed in this invention by preloading its radial and circumferentially placed straight structural members and hence it is termed as preloaded parabolic dish antenna. Such a preloading results in considerable reduction in its weight and also to the effort involved in its assembly. The back-up structure of the preloaded parabolic dish antenna is made of a central hub, an assembly of a suitable number of elastically bent radial structural members connected rigidly to the central hub and to the same number of straight structural members which are connected to the tips of the radial members at the outer rim of the dish and also to straight bracing members placed circumferentially at intermediate locations, which are all tensioned to specified prestress values in the absence of wind loading. The outermost rim members placed at the periphery of the dish form the aperture of the dish.

Abstract: The present invention is directed, inter alia, to a switch comprising: (A) a superconducting material whose field cooled and zero field cooled ac permittivities differ from each other, and whose field cooled and zero field cooled ac susceptibilities differ from each other, in a range of temperature below the superconducting transition temperature of the material; (B) means for applying a static magnetic field to said material; (C) means for controllably applying to said material an oscillating magnetic field of a magnitude effective to convert said material from a state exhibiting filed cooled permittivity to a state exhibiting zero field cooled permittivity; and (D) means for applying to said material a heat pulse effective to convert said material from a state exhibiting zero field cooled permittivity to a state exhibiting field cooled permittivity, said switch operating between a superconducting zero field cooled state and a superconducting field cooled state.