Patents Assigned to Technology Development Center
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Publication number: 20230400849Abstract: A water surface and underwater dual-purpose automatic positioning and tracking system and method, which belongs to the field of marine environment observation technologies. The positioning and tracking system includes: a rope winding and unwinding structure, arranged on a main hull structure; where the rope winding and unwinding structure includes a rope roller and a winding and unwinding rope wound around the rope roller; an auxiliary positioning remote control ship, located outside a main body of the main hull structure, where the auxiliary positioning remote control ship is in transmission and fixed connection with the winding and unwinding rope away from the rope roller; communication control units, arranged on the main hull structure and the auxiliary positioning remote control ship; and an automatic positioning tracker unit, arranged on the hull structure, where the automatic positioning tracker unit is in remote communication connection with the communication control units.Type: ApplicationFiled: March 6, 2023Publication date: December 14, 2023Applicants: FIRST INSTITUTE OF OCEANOGRAPHY, MINISTRY OF NATURAL RESOURCES, QINGDAO NATIONAL LABORATORY FOR MARINE SCIENCE AND TECHNOLOGY DEVELOPMENT CENTERInventors: Guanlin WANG, Yanfeng WANG, Guanhui LIANG, Shujiang LI
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Patent number: 11829132Abstract: A water surface and underwater dual-purpose automatic positioning and tracking system and method, which belongs to the field of marine environment observation technologies. The positioning and tracking system includes: a rope winding and unwinding structure, arranged on a main hull structure; where the rope winding and unwinding structure includes a rope roller and a winding and unwinding rope wound around the rope roller; an auxiliary positioning remote control ship, located outside a main body of the main hull structure, where the auxiliary positioning remote control ship is in transmission and fixed connection with the winding and unwinding rope away from the rope roller; communication control units, arranged on the main hull structure and the auxiliary positioning remote control ship; and an automatic positioning tracker unit, arranged on the hull structure, where the automatic positioning tracker unit is in remote communication connection with the communication control units.Type: GrantFiled: March 6, 2023Date of Patent: November 28, 2023Assignees: FIRST INSTITUTE OF OCEANOGRAPHY, MINISTRY OF NATURAL RESOURCES, QINGDAO NATIONAL LABORATORY FOR MARINE SCIENCE AND TECHNOLOGY DEVELOPMENT CENTERInventors: Guanlin Wang, Yanfeng Wang, Guanhui Liang, Shujiang Li
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Patent number: 11759471Abstract: The present invention is concerned with a modified release pharmaceutical composition comprising an effective amount of at least one antipsychotic agent so that the antipsychotic agent(s) are released in such a manner to better accord with physiological and chronotherapeutic requirements of patients.Type: GrantFiled: April 10, 2020Date of Patent: September 19, 2023Assignee: MEDICAL AND PHARMACEUTICAL INDUSTRY TECHNOLOGY AND DEVELOPMENT CENTERInventors: Shih-Ku Lin, Chih-Chiang Yang, Tse-Ching Lin, Lai-Cheng Chin, Pei Hsuan Ho
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Patent number: 11500384Abstract: The invention relates to a method and system for path planning of a wave glider, comprising acquiring historical navigation data of the glider and an underwater vehicle via a shore-based monitoring center; fitting historical navigation data nonlinearly by a deep learning neural network to obtain a trained network; acquiring real-time navigation data of the glider at an off-line end, real-time navigation data and predetermined shipping track data of the vehicle; obtaining the set of off-line optimized path planning schemes of the glider by the above data and the trained network; and determining an optimal path planning scheme of the glider by the deep learning neural network according to real-time data and constraint data of the glider at the on-line end. The invention can reasonably plan the path of the glider and ensure continuous and reliable information interaction between the glider and the vehicle.Type: GrantFiled: April 15, 2020Date of Patent: November 15, 2022Assignees: NATIONAL DEEP SEA CENTER, QINGDAO NATIONAL LABORATORY FOR MARINE SCIENCE AND TECHNOLOGY DEVELOPMENT CENTERInventors: Tongwei Zhang, Lei Yan, Haibing Li, Xiujun Sun, Xianglin Xu, Jingxiao Liu, Lei Yang, Shengjie Qin
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Patent number: 11473335Abstract: An acoustic-electric remote control release hook used on water and underwater includes a first shell and a cylindrical framework. The cylindrical framework is fixedly connected with the first shell in a detachable mode; the first underwater transducer is remotely matched with a second water transducer which extends to the underwater through a cable, and the second water transducer is connected with a control switch through a cable. An acoustic command receiving module is arranged inside the first shell, and a power supply end of the acoustic command receiving module is connected with the power supply. A signal input end of the acoustic command receiving module is connected with the first underwater transducer through a cable and a watertight connector assembly, and a signal output end of the acoustic command receiving module is connected with the driver of the direct-current motor.Type: GrantFiled: January 6, 2022Date of Patent: October 18, 2022Assignees: FIRST INSTITUTE OF OCEANOGRAPHY, MINISTRY OF NATURAL RESOURCES, QINGDAO NATIONAL LABORATORY FOR MARINE SCIENCE AND TECHNOLOGY DEVELOPMENT CENTERInventors: Guanlin Wang, Shujiang Li, Guanhui Liang, Fengjun Wang
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Patent number: 11305854Abstract: A deep-sea low-cost long-endurance collaborative navigation and positioning system. A shore-based monitoring center transmits a route planning solution to a wave glider. The wave glider follows an underwater vehicle to travel and feeds back state information of the wave glider and state information of the underwater vehicle to the shore-based monitoring center in real time. The shore-based monitoring center adjusts the route planning solution according to the state information in real time. The wave glider and the underwater vehicle are respectively equipped with an underwater acoustic communication machine.Type: GrantFiled: April 15, 2020Date of Patent: April 19, 2022Assignees: NATIONAL DEEP SEA CENTER, QINGDAO NATIONAL LABORATORY FOR MARINE SCIENCE AND TECHNOLOGY DEVELOPMENT CENTER, TECHNOLOGY DEVELOPMENT CENTERInventors: Tongwei Zhang, Guangjie Han, Lei Yan, Haibing Li, Xiujun Sun, Shuai Zhang, Jingxiao Liu, Lei Yang
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Publication number: 20210284305Abstract: A deep-sea low-cost long-endurance collaborative navigation and positioning system. A shore-based monitoring center transmits a route planning solution to a wave glider. The wave glider follows an underwater vehicle to travel and feeds back state information of the wave glider and state information of the underwater vehicle to the shore-based monitoring center in real time. The shore-based monitoring center adjusts the route planning solution according to the state information in real time. The wave glider and the underwater vehicle are respectively equipped with an underwater acoustic communication machine.Type: ApplicationFiled: April 15, 2020Publication date: September 16, 2021Applicants: National Deep Sea Center, Qingdao National Laboratory for Marine Science and Technology Development CenterInventors: Tongwei ZHANG, Guangjie HAN, Lei YAN, Haibing LI, Xiujun SUN, Shuai ZHANG, Jingxiao LIU, Lei YANG
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Publication number: 20210286361Abstract: The invention relates to a method and system for path planning of a wave glider, comprising acquiring historical navigation data of the glider and an underwater vehicle via a shore-based monitoring center; fitting historical navigation data nonlinearly by a deep learning neural network to obtain a trained network; acquiring real-time navigation data of the glider at an off-line end, real-time navigation data and predetermined shipping track data of the vehicle; obtaining the set of off-line optimized path planning schemes of the glider by the above data and the trained network; and determining an optimal path planning scheme of the glider by the deep learning neural network according to real-time data and constraint data of the glider at the on-line end. The invention can reasonably plan the path of the glider and ensure continuous and reliable information interaction between the glider and the vehicle.Type: ApplicationFiled: April 15, 2020Publication date: September 16, 2021Applicants: NATIONAL DEEP SEA CENTER, QINGDAO NATIONAL LABORATORY FOR MARINE SCIENCE AND TECHNOLOGY DEVELOPMENT CENTERInventors: Tongwei ZHANG, Lei YAN, Haibing LI, Xiujun SUN, Xianglin XU, Jingxiao LIU, Lei YANG, Shengjie QIN
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Patent number: 10940113Abstract: A pharmaceutical composition for colon targeting, a method for treating a colon-related disease using the same and a preparation method thereof are disclosed. The pharmaceutical composition of the present disclosure comprises: a core matrix comprising a cross-linked hydrogel and an active ingredient, wherein the active ingredient is dispersed in the cross-linked hydrogel, and a content of the active ingredient is 65 wt % to 95 wt % based on a total weight of the core matrix.Type: GrantFiled: February 22, 2018Date of Patent: March 9, 2021Assignee: MEDICAL AND PHARMACEUTICAL INDUSTRY TECHNOLOGY AND DEVELOPMENT CENTERInventors: Chih-Chiang Yang, Wen-Che Wang, Chiao-Ling Hsu
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Publication number: 20190388340Abstract: Disclosed herein is an oral dosage formulation suitable for treating a neurodegenerative disorder. The oral dosage formulation contains both sustained-release and immediate-release drugs. The sustained-release drug in the oral dosage formulation is memantine, and the immediate-release drug in the oral dosage formulation is donepezil and/or memantine, and the formulation is characterized in having a pH-independent dissolution profile of memantine at a pH range from about 1.0 to about 7.0.Type: ApplicationFiled: June 20, 2019Publication date: December 26, 2019Applicants: Center Laboratories, Inc., Medical and Pharmaceutical Industry Technology and Development CenterInventors: Meng-Ju LEE, Shu-Hsien CHANG, Chih-Chiang YANG, Yuan-Chih LE, Tse-Ching LIN, Ko-Chiang CHEN, Lai-Cheng CHIN, Tai-Yin KE, Pei-Ying LIAO
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Patent number: 10428456Abstract: Disclosed is a steel wire rope for conveyor belts. The steel wire rope includes a central steel wire, a steel wire layer externally wound on the central steel wire, and a plurality of external steel wire strands. Each external steel wire strand includes a core steel wire and N external steel wires. The central steel wire, the steel wire layer externally wound on the central steel wire, and the plurality of external steel wire strands are wound into a steel wire rope for conveyor belts in one step. The steel wire layer is externally wound on the outer side of the central steel wire, the external steel wire strands are wound to wrap the outer side of the steel wire layer, and the external steel wire strands are in line contact with the steel wire layer.Type: GrantFiled: September 10, 2014Date of Patent: October 1, 2019Assignees: JIANGSU FASTEN TECHNOLOGY DEVELOPMENT CENTER CO., LTD, JIANGSU FASTEN SPECIAL STEEL PRODUCTS CO., LTDInventors: Lihua Liu, Chunlei Zhang, Hongfang Liu, Yongqing Shao, Yawei Zhang, Kai Xu, Yi Lu
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Patent number: 9359738Abstract: The present invention relates to a quick coupling for pipe pile, comprising an upper end plate, a lower end plate and a screw hook made of spring steel for coupling the upper and lower end plate, a plurality of tapped holes are uniformly provided on the upper end plate, a plurality of holes corresponding to the tapped holes are provided on the lower end plate, a lock hole is positioned at the lower portion of the hole, while the cross-section area of the lock hole is bigger than the cross-section area of the hole. One end of the screw hook is provided with a screw end mating with the tapped hole on the upper end plate, while the other end is provided with a hook end mating with the lock hole on the lower end plate, whereby the upper and lower end plate can be coupled firmly.Type: GrantFiled: August 27, 2014Date of Patent: June 7, 2016Assignees: Guangzhou Institute of Building Science Co., Ltd., Technology Development Center of Guangzhou Institute of Building Science Co., Ltd.Inventors: Yuliang Qi, Mengxiong Tang, Hesong Hu
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Publication number: 20150306167Abstract: Disclosed herein is the use of an extract from Alpinia spp. for the preparation of a medicament for the treatment of irritable bowel syndrome (IBS). The extract is prepared by extracting fresh and/or dried fruits of Alpinia spp. plant with a solvent such as a supercritical fluid, water, 10-95% (v/v) ethanol, acetone, ethyl acetate or n-hexane, to obtain an extract suitable for the preparation of IBS medicaments. In some embodiments, active compounds with anti-abnormal defecation activity and/or analgesia effect are isolated from the water extract of Alpinia spp.; these compounds are therefore potential lead compounds for use as medicaments for treating IBS.Type: ApplicationFiled: December 30, 2013Publication date: October 29, 2015Applicant: Medical and Pharmaceutical Industry Technology and Development CenterInventors: Jui-Ching CHEN, Che-Yi LIN, Chih-Sheng HUNG, Pei-Fan WU, Fen CHEN
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Patent number: 9144590Abstract: Disclosed herein is the use of an extract from an Aster species for the preparation of a medicament for the treatment of opioid-induced constipation. The extract is extracted from fresh and/or dried roots and rhizomes of a Tatarian aster (Aster tartaricus) plant, in which the extraction uses water or 40-95% (v/v) ethanol as an extractant to obtain an extraction mixture. In some embodiments, the extraction mixture is then eluted with water followed by at least one eluent.Type: GrantFiled: December 23, 2011Date of Patent: September 29, 2015Assignee: Medical and Pharmaceutical Industry Technology and Development CenterInventors: Jui-Ching Chen, Che-Yi Lin, Chien-Chang Wu, Cheng-Po Huang, Yuan-Ling Ku, Yueh-Chu Chen, Yu-Hsuan Lin, Chih-Sheng Hung
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Publication number: 20140314867Abstract: A vitamin K2 microsphere. The microsphere includes a poly(lactide-co-glycolide) acid (PLGA) particle, in which the Mw of PLGA is between 1000 and 300000, and the molar ratio between the lactide repeat units and the glycolide repeate unit is 1-9:9-1; and one or more vitamin K2 molecules are embedded in the PLGA particle, wherein the vitamin K2 is present in an amount of 0.005-75 wt %, based on the weight of the microsphere. Also disclosed are a method of preparing the vitamin K2 microsphere, a method of treating osteoporosis using this microsphere, and a pharmaceutical composition containing the microsphere.Type: ApplicationFiled: April 22, 2014Publication date: October 23, 2014Applicant: Medical and Pharmaceutical Industry Technology and Development CenterInventors: Shu-Wen Whu, Chung-Chih Cheng, Chih-Chiang Yang
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Patent number: 8470379Abstract: A new use of a potent product extracted from rhizomes of Zingiber officinale in treating a disease associated with Helicobacter pylori such as gastritis, gastric ulcer or duodenal ulcer in a patient. The potent product is prepared by a process including the steps of a) preparing a crude extract from rhizomes of Zingiber officinale, said crude extract comprising 6-gingerol and 6-shogaol; b) introducing the crude extract to a normal phase chromatography column, and eluting the column with a first eluent having a polarity lower than that of a mixture of n-hexane and ethyl acetate in a weight ratio of 6:4 to obtain a potent fraction. Preferably, the potent fraction is substantially free of both 6-gingerol and 6-shogaol.Type: GrantFiled: October 25, 2010Date of Patent: June 25, 2013Assignee: Medical and Pharmaceutical Industry Technology and Development CenterInventors: Feng-Nien Ko, Mo-Chi Cheng, Cheng-Ko Liu, Jen-Wei Chen, Fen Chen, Chao-Chi Yei
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Patent number: 8433557Abstract: Both a system and method are provided for transliterating a name written in the letters of an alphabet of a source language to a name in the letters of an alphabet of a target language. The system includes instructions to determine whether the letters of the alphabets of the source and target languages are the same. If so, the instructions transliterate the name into the same letters used in the source language alphabet. If not, the instructions (1) determine the sound associated with each of the letters of the source language that form the name; (2) transliterate the letters into letters of the International Phonetic Alphabet (IPA) to create a same or similar sounding name in the letters of the IPA; (3) determine the sound associated with each of the letters of the target language, and (4) transliterate the letters of the IPA form into letters of the target language.Type: GrantFiled: July 28, 2010Date of Patent: April 30, 2013Assignee: Technology Development Center, King Abdulaziz City for Science and TechnologyInventor: Mansour M. Alghamdi
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Patent number: 8394739Abstract: A method and adsorbent composition for removing heavy metals from contaminated water, including mixing a water having a concentration of one or more heavy metals with an adsorbent including granules of a mixture of 3.33 wt % bentonite clay and a siwak stick powder; and collecting water having a reduced concentration of the heavy metal(s).Type: GrantFiled: July 14, 2010Date of Patent: March 12, 2013Assignee: Technology Development Center, King Abdulaziz City for Science and TechnologyInventor: Saad A. Al-Jlil
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Patent number: 8257759Abstract: An antitussive composition is provided. A pharmaceutical composition for relieving, preventing and/or treating a cough includes a sufficient amount of the Morus australis Poir extract as an active component. The effective Morus australis Poir extract is prepared by extracting the root-bark of the Morus australis Poir with water, ethanol, acetone, ethyl acetate, or a combination thereof. The crude extract can be further fractioned by ultrafiltration or reverse phase column.Type: GrantFiled: December 25, 2008Date of Patent: September 4, 2012Assignee: Medical and Pharmaceutical Industry Technology and Development CenterInventors: Yuan-Ling Ku, Chien-Jen Shih, Hsiao-Chu Huang, Chun-Hung Kuo, Yi-Chen Lin, Yueh-Chu Chen, Feng-Nien Ko
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Patent number: 8226981Abstract: A method of preparing a taste-masking oral dosage form is provided. The method includes providing a first solution comprising a pharmaceutically active ingredient and a starch, providing a second solution comprising a hydrophilic polymer and a surfactant, blending the first and second solution to form a plurality of microparticles by a granulating process, wherein the microparticle is a co-crystal structure comprising the pharmaceutically active ingredient and the starch, and performing a compression-molding process to form the tablet.Type: GrantFiled: September 5, 2007Date of Patent: July 24, 2012Assignee: Medical and Pharmaceutical Industry Technology and Development CenterInventors: Chih-Chiang Yang, Wen-Che Wang, Hui-Yu Chen