Abstract: Ordered (e.g., self-assembled) structures, arranged from peptide nucleic acids and/or analogs thereof, are disclosed. The peptide nucleic acids forming the ordered structures comprise from 1 to 10 PNA backbone units, at least one comprising a guanine nucleobase or an analog thereof. Processes of generating the ordered structures, uses thereof and articles-of manufacturing, devices and systems containing same are also disclosed.
Type:
Application
Filed:
July 13, 2017
Publication date:
October 26, 2017
Applicant:
Technology Innovation Momentum Fund (Israel) Limited Partnership
Inventors:
Or BERGER, Lihi ADLER-ABRAMOVICH, Ehud GAZIT
Abstract: Ordered (e.g., self-assembled) structures, arranged from peptide nucleic acids and/or analogs thereof, are disclosed. The peptide nucleic acids forming the ordered structures comprise from 1 to 10 PNA backbone units, at least one comprising a guanine nucleobase or an analog thereof. Processes of generating the ordered structures, uses thereof and articles-of manufacturing, devices and systems containing same are also disclosed.
Type:
Grant
Filed:
May 1, 2014
Date of Patent:
August 22, 2017
Assignee:
Technology Innovation Momentum Fund (Israel) Limited Partnership
Inventors:
Or Berger, Lihi Adler-Abramovich, Ehud Gazit
Abstract: Energetic nitrogen-rich monomers represented by the general Formula I: wherein each of X1 and X2 is independently NR or a covalent bond. R is H or C1-4 alkyl, each of T1 and T2 is independently a moiety selected from the group consisting of a triazole moiety, a tetrazole moiety and a guanidine moiety, at least one of T1 and T2 being substituted by at least one polymerizable group, are disclosed herein, as well as polymers based thereon, and uses of such polymers.
Type:
Application
Filed:
October 28, 2015
Publication date:
August 10, 2017
Applicant:
Technology Innovation Momentum Fund (Israel) Limited Partnership
Inventors:
Michael GOZIN, Alex AIZIKOVICH, Avital SHLOMOVICH, Adva COHEN, Tali PECHERSKY
Abstract: Hybrid hydrogels formed of a plurality of peptides that are capable of self-assembling into a hydrogel in an aqueous solution and a biocompatible polymer that is characterized by high swelling capability, high elasticity and low mechanical strength are disclosed, with exemplary hybrid hydrogels being formed of a plurality of aromatic dipeptides and hyaluronic acid. The hybrid hydrogels are characterized by controllable mechanical and biological properties which can be adjusted by controlling the concentration ratio of the peptides and the polymer, and which average the mechanical and biological properties of the peptides and the polymer. Processes of preparing the hydrogels and uses thereof in pharmaceutical, cosmetic or cosmeceutic applications such as tissue engineering and/or regeneration are further disclosed.
Type:
Application
Filed:
March 20, 2017
Publication date:
July 6, 2017
Applicant:
Technology Innovation Momentum Fund (Israel) Limited Partnership
Abstract: An imaging system color image acquisition including: an image sensor; a tunable spectral filter arranged in an optical path of light propagation towards the image sensor; and a controller connected to the image sensor and to the tunable spectral filter. The controller is configured and operable for generating a colored image by sequentially operating the tunable spectral filter for sequentially filtering light passing towards the image sensor with three or more different spectral filtering curves during three or more corresponding integration time durations. The tunable spectral filter is configured, as an etalon and includes a pair of reflective surfaces. At least one of the reflective surfaces includes a layer of high refractive index of at least n=2.3 or even higher than 3, or a layer of low refractive index, smaller than n=1.
Type:
Grant
Filed:
June 24, 2014
Date of Patent:
May 16, 2017
Assignee:
TECHNOLOGY INNOVATION MOMENTUM FUND (ISRAEL) LIMITED PARTNERSHIP
Abstract: Hybrid hydrogels formed of a plurality of peptides that are capable of self-assembling into a hydrogel in an aqueous solution and a biocompatible polymer that is characterized by high swelling capability, high elasticity and low mechanical strength are disclosed, with exemplary hybrid hydrogels being formed of a plurality of aromatic dipeptides and hyaluronic acid. The hybrid hydrogels are characterized by controllable mechanical and biological properties which can be adjusted by controlling the concentration ratio of the peptides and the polymer, and which average the mechanical and biological properties of the peptides and the polymer. Processes of preparing the hydrogels and uses thereof in pharmaceutical, cosmetic or cosmeceutic applications such as tissue engineering and/or regeneration are further disclosed.
Type:
Grant
Filed:
July 6, 2015
Date of Patent:
April 4, 2017
Assignee:
Technology Innovation Momentum Fund (Israel) Limited Partnership
Abstract: Described is a superconductive layered structure and an article including this superconductive layered structure on a substrate structure. The superconductive layered structure comprises a stack including at least one bi-layered assembly formed by first and second layers of similar superconducting material compositions, the second layer being superconductive at predetermined temperature condition, the first layer being a substantially thin layer and having a c lattice parameter selected in accordance with those of the substrate structure and the second layer, such that said first layer is non-superconductive at said predetermined temperature condition thereby allowing the second superconductive layer to be desirably thick to provide high critical current density of the superconductive layer.
Type:
Grant
Filed:
February 11, 2014
Date of Patent:
May 24, 2016
Assignee:
TECHNOLOGY INNOVATION MOMENTUM FUND (ISRAEL) LIMITED PARTNERSHIP
Inventors:
Guy Deutscher, Mishael Azoulay, Boaz Almog
Abstract: Hybrid hydrogels formed of a plurality of peptides that are capable of self-assembling into a hydrogel in an aqueous solution and a biocompatible polymer that is characterized by high swelling capability, high elasticity and low mechanical strength are disclosed, with exemplary hybrid hydrogels being formed of a plurality of aromatic dipeptides and hyaluronic acid. The hybrid hydrogels are characterized by controllable mechanical and biological properties which can be adjusted by controlling the concentration ratio of the peptides and the polymer, and which average the mechanical and biological properties of the peptides and the polymer. Processes of preparing the hydrogels and uses thereof in pharmaceutical, cosmetic or cosmeceutic applications such as tissue engineering and/or regeneration are further disclosed.
Type:
Application
Filed:
July 6, 2015
Publication date:
October 29, 2015
Applicant:
Technology Innovation Momentum Fund (Israel) Limited Partnership
Abstract: Hybrid hydrogels formed of a plurality of peptides that are capable of self-assembling into a hydrogel in an aqueous solution and a biocompatible polymer that is characterized by high swelling capability, high elasticity and low mechanical strength are disclosed, with exemplary hybrid hydrogels being formed of a plurality of aromatic dipeptides and hyaluronic acid. The hybrid hydrogels are characterized by controllable mechanical and biological properties which can be adjusted by controlling the concentration ratio of the peptides and the polymer, and which average the mechanical and biological properties of the peptides and the polymer. Processes of preparing the hydrogels and uses thereof in pharmaceutical, cosmetic or cosmeceutic applications such as tissue engineering and/or regeneration are further disclosed.
Type:
Grant
Filed:
June 2, 2011
Date of Patent:
July 7, 2015
Assignee:
Technology Innovation Momentum Fund (Israel) Limited Partnership