Abstract: The present invention relates to a new method of preparing acellularized, biocompatible, implantation material starting from a biological material. In particular, the present invention relates to a method of preparing biological material for implantation comprising (a) fixation of the biological material with an aldehyde and (b) detoxification/anticalcification of the fixed biological material, wherein the detoxification/anticalcification step makes use of a novel class of substances of formula: NH2—(CH2)n—X ??(I) wherein X is COOH, SO3H, PO3H2 and n is an integer from 2 to 6.
Type:
Application
Filed:
May 22, 2006
Publication date:
November 22, 2007
Applicant:
TECNOBIOMEDICA S.P.A.
Inventors:
Corrado Piconi, Stefano Rinaldi, Leopoldo Della Ciana, Antonella Motta
Abstract: Described herein is a pulsator device that can be used for generating a pulsed flow starting from a substantially constant flow, for example in reactors for cell growth and other applications in which it is desired to have available pulsed irroration flows. The device comprises a deformable body that is able to define a duct for passage of a substantially constant flow of a fluid subjected to pumping. Associated to the deformable body is at least one actuation chamber that is selectively expandable between at least one contracted condition and at least one extended condition of pumping so as to produce a variation of the section for passage of said fluid through the duct. The variation of the section of passage through the duct is able to cause the generation of a pulsed flow of the fluid subjected to pumping.
Type:
Application
Filed:
December 22, 2005
Publication date:
October 26, 2006
Applicant:
Tecnobiomedica S.p.A.
Inventors:
Stefano Rinaldi, Maurizio Zagara, Luigi Carotenuto
Abstract: The compound of formula is useful as chain extender in the preparation of polymers, in particular of linear and cross-linkable, heparinizable, biocompatible polymers.
Abstract: The compound of formula ##STR1## is useful as chain extender in the preparation of polymers, in particular of linear and cross-linkable, heparinizable, biocompatible polymers.