Patents Assigned to Texas Biotechnology Corporation, Inc.
  • Compounds that inhibit the binding of integrins to their receptors
    Patent number: 6096773
    Abstract: A method for the inhibition of the binding of .alpha..sub.4 .beta..sub.1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions comprising such compounds; and the use of such compounds either as above, or in formulations for the control or prevention of diseases states in which .alpha..sub.4 .beta..sub.1 is involved.
    Type: Grant
    Filed: April 15, 1999
    Date of Patent: August 1, 2000
    Assignee: Texas Biotechnology Corporation, Inc.
    Inventors: Ian L. Scott, Bore G. Raju, Ronald J. Biediger, Vanessa O. Grabbe, Jamal Kassir, Karin M. Keller, Timothy P. Kogan, deceased, Shuqun Lin, Robert V. Market