Abstract: The present invention describes a bio-based process to produce high quality protein concentrate (HQPC) by converting plant derived celluloses into bioavailable protein via aerobic incubation, including the use of such HQPC so produced as a nutrient, including use as a fish meal replacement in aquaculture diets.

Abstract: The present disclosure addresses limitations in ferritic materials. In at least one aspect, the present disclosure provides core-shell nanoparticles exhibiting improved characteristics for implementations and adoptability in numerous applications. Further aspects of the disclosure provide core-shell nanoparticles for use in electronic, magnetic and electro-magnetic applications. Still, other aspects of the present disclosure provide core-shell nanoparticles for a thermochemical water-splitting reaction resulting in increased H2 volume generation during multiple thermochemical cycles.

Abstract: Chemical compounds that inhibit cancer cell growth are provided. The compounds are heteroarotinoids and derivatives thereof with oxygen, nitrogen or sulfur in chroman systems, tetrahydroquinoline systems, and tetrahydrothiochroman systems.

Abstract: Neural interfaces with the peripheral nervous system have been developed to provide a direct communication pathway between peripheral nerves and prosthetic limbs. Described herein is a method of making a microchannel integrated neural interface device comprising a plurality of hollow cylindrical electrodes in a PDMS scaffold, which can control the reinnervated muscles and interpret neurological signals. The acquired bioelectrical signals can be used for the interpretation of mind and create a neural map.

Abstract: Embodiments of the invention include methods of identifying microorganisms and/or diagnosing infections in subjects cause by microorganisms. Embodiments of the invention may also include further characterizing (e.g., determining the presence of one or more antibiotic resistance markers) the microorganisms and determining a strain identity of the microorganisms.

Abstract: A device, system, and method for small scale CO2 extraction is disclosed. The device includes a sorbent bed having a sorbent resin. The device also includes a blower in fluid communication with the sorbent bed through at least one duct, as well as a collection tray beneath the sorbent bed and having a drain. The device also includes a capture configuration and a regeneration configuration. The capture configuration includes an air flow driven by the blower passing through the sorbent resin. The regeneration configuration includes the flooding of at least the sorbent resin with regeneration fluid. The regeneration fluid has a higher dissolve inorganic carbon concentration after flooding the sorbent resin. Multiple devices may be employed together as a system capable of providing a continuous product stream having an upgraded concentration of CO2.

Abstract: 3D MRI images of the brain may be created and acquired. After administration of contrast, brain lesions and other abnormalities may be identified and isolated from the 3D MRI images, with each lesion serving as a region of interest (ROI). 3D region of contrast enhancement images may be created from segmented 3D MRI images and different regions of contrast enhancement of the brain lesion may be depicted. Saved regions of contrast enhancement may be converted into stereolithography format, maximum intensity projection (MIP) images, and/or orthographic projection images. Data corresponding to these resulting 3D region of contrast enhancement images may be used to create 3D printed models of the isolated region of contrast enhancement. Analysis of the 3D brain region of contrast enhancement images and the 3D printed region of contrast enhancement models may enable a more efficient and accurate way of determining brain lesion risk factors and effective treatment regimens.

Abstract: Duchenne muscular dystrophy (DMD) is a fatal muscle disease caused by the lack of dystrophin, which maintains muscle membrane integrity. Provided herein are methods of using adenine base editor (ABE) to modify splice sites of the dystrophin gene, causing skipping or refraining of common DMD exon deletion mutations, restoring dystrophin expression. Also provided herein are methods of using prime editing to reframe the dystrophin open reading frame and restore dystrophin expression.

Abstract: A method and system for downloading the information stored on an IoT device is presented. All in-system programming pins are identified by inspection with visible light or using a computed tomography scan of the device using X-radiation. Based on this inspection, a 3D fixture is fabricated that accommodates spring-loaded pin connectors for contacting the identified in-system programming taps on the main printed circuit board of the device. The 3D test jig, in conjunction with a logic analyzer, can extract data from the internet of things (IoT) device.

Abstract: In an aspect of the present invention, a new active optic is provided, namely, a photo-magnetically actuated deformable mirror (PMADM) made of a magnetic composite structure and an optical quality substrate layer. The magnetic layer is composed of Polydimethylsiloxane (PDMS) and powdered ferromagnetic CrO2. A magnet may be used to deform the mirror surface. The powdered CrO2 has a low Curie temperature (preferably around 395 K) which allows changing the magnetization of the magnetic layer using a laser heating source, thus providing control over the deformation. In one embodiment, the structure has an overall dimension of 1.2 inch 1.2 inch 175 ?m with an optical pupil diameter of 8 mm. The PMADM is estimated to deform to a maximum stroke of 8.7731 ?m before failure with a 3 safety factor.

Abstract: A photonic device including a first waveguide and a second waveguide is provided. The device includes an interconnect coupled with the first waveguide and the second waveguide. The interconnect includes a substrate. The interconnect includes a film including a refractive index contrast (RIC) polymer and a core. The core includes a first domain having a first refractive index. The core includes a second domain adjacent to the first domain and having a second refractive index. The second refractive index is less than the first refractive index. The core includes a third domain adjacent to the second domain and having a third refractive index. The third refractive index is less than the second refractive index. The second domain is disposed between the first domain and the third domain. The refractive index of the substrate is less than the first refractive index, the second refractive index, and the third refractive index.

Abstract: Apparatus and methods for imaging a region of a subject comprising an artifact. In certain embodiments, the apparatus and methods utilize computed tomography (CT) scans obtained at two different angles to image a region posterior to an artifact.

Abstract: The present disclosure provides a method of biocementation comprising contacting a granular, cohesionless soil with a solution, wherein the solution comprises urea, urease, a source of calcium ions, and a source of non-urease proteins, wherein the urea, urease, source of calcium ions, and source of non-urease proteins are provided in effective amounts suitable to cause crystallization of calcium carbonate.

Abstract: Various embodiments for systems and methods for decentralized multi-target tracking with multiple robots using a PHD filter are disclosed herein.

Abstract: A device for ion chromatography comprises a tube with an inlet opening and an outlet opening and an inner diameter from about 40 microns to about 10 microns. There is an aperture through one side of the tube into a lumen of the tube. At least a portion of the inner surface of the tube has a first charge. An ion exchange barrier covers the aperture on an outside surface of the tube. The inner surface of the tube, from the inlet opening to the aperture, is coated with ion exchange particles having a diameter ranging from about 30 nm to about 200 nm. The ion exchange particles have a second charge opposite the first charge. The inner surface of the tube, from the outlet opening to the aperture, is not coated with ion exchange particles.

Abstract: Disclosed are small molecule PTPRD inhibitors and uses thereof. Methods of using the PTPRD inhibitors include methods of treating, preventing, or delaying the progression of a disorder responsive to PTPRD inhibition, including for example nicotine dependence, addiction, obesity, metabolic syndrome, and substance-use disorders such as stimulant-use disorders and opioid-use disorders.

Abstract: Position information estimation in a distributed radio frequency (RF) communications system is provided. Embodiments disclosed herein facilitate high-precision estimations of positions, orientations, velocities, and acceleration of network nodes in a distributed RF network (e.g., including base stations and vehicles, such as aircraft or unmanned aerial systems (UASs)). Modern radio systems must adapt to limited spectral access by reducing spectrum demand and increasing operational efficiency. In this regard, an RF system is provided which simultaneously performs positioning and communications tasks. This system specifically addresses the issue of spectral congestion by employing an extremely efficient positioning strategy and using a joint waveform that simultaneously enables both tasks. This efficiency in turn supports more users in a given frequency allocation.

Abstract: An electrical device, comprising a softening polymer layer, an electrode layer on a surface of the softening polymer layer and a cover polymer layer on the surface of the softening polymer layer. An opening in the polymer cover layer is filled with a reflowed solder, one end of the reflowed solder, located inside the opening, contacts a contact pad site portion of the electrode layer, and another end of the reflowed solder contacts an electrical connector electrode of the device.

Abstract: Remote recovery of acoustic signals from passive sources is provided. Wideband radars, such as ultra-wideband (UWB) radars can detect minute surface displacements for vibrometry applications. Embodiments described herein remotely sense sound and recover acoustic signals from vibrating sources using radars. Early research in this domain only demonstrated single sound source recovery using narrowband millimeter wave radars in direct line-of-sight scenarios. Instead, by using wideband radars (e.g., X band UWB radars), multiple sources separated in ranges are observed and their signals isolated and recovered. Additionally, the see-through ability of microwave signals is leveraged to extend this technology to surveillance of targets obstructed by barriers. Blind surveillance is achieved by reconstructing audio from a passive object which is merely in proximity of the sound source using clever radar and audio processing techniques.

Abstract: In one aspect, compositions and wound dressings are described herein. In some embodiments, a composition or wound dressing described herein comprises a mesh formed from a plurality of biodegradable polymer fibers; a first active agent dispersed in the biodegradable polymer fibers; a plurality of biodegradable polymer particles disposed in the mesh; and a second active agent dispersed in the biodegradable polymer particles. The particles can be disposed within the interiors of the fibers of the mesh or between the fibers of the mesh. In another aspect, a composition or wound dressing described herein comprises a first perforated mesh formed from a first plurality of biodegradable polymer fibers; and a second perforated mesh formed from a second plurality of biodegradable polymer fibers, wherein the second perforated mesh is disposed on the first perforated mesh in a stacked configuration and the first and second perforated meshes have different degrees of perforation.