Patents Assigned to The Board of Rijks Universiteit Leiden
  • Probes for detecting activated RAS oncogenes
    Patent number: 5847095
    Abstract: Molecules complementary to nucleotide sequences encoding mutant ras proteins which contain a single-base mutation in the codon encoding amino acids at position 13, 12 or 61 have been produced. These molecules are useful in methods of detecting specific single-base mutations in altered ras genes and the specific cancers associated with such mutations.
    Type: Grant
    Filed: January 3, 1997
    Date of Patent: December 8, 1998
    Assignee: The Board of Rijks Universiteit Leiden
    Inventors: Johannes L. Bos, Alex J. van der Eb
  • Methods for detecting activated RAS oncogenes
    Patent number: 5591582
    Abstract: Molecules complementary to nucleotide sequences encoding mutant ras proteins which contain a single-base mutation in the codon encoding amino acids at position 13, 12 or 61 have been produced. These molecules are useful in methods of detecting specific single-base mutations in altered ras genes and the specific cancers associated with such mutations.
    Type: Grant
    Filed: June 23, 1994
    Date of Patent: January 7, 1997
    Assignee: The Board of Rijks Universiteit Leiden
    Inventors: Johannes L. Bos, Alex J. van der Eb
  • Probes and methods for detecting activated ras oncogenes
    Patent number: 4871838
    Abstract: Molecules complementary to nucleotide sequences encoding mutant ras protiens which contain a single-base mutation in the codon encoding amino acids at position 13, 12 or 61 have been produced. These molecules are useful in methods of detecting specific single-base mutations in altered ras genes and the specific cancers associated with such mutations.
    Type: Grant
    Filed: July 23, 1985
    Date of Patent: October 3, 1989
    Assignee: The Board of Rijks Universiteit Leiden
    Inventors: Johannes L. Bos, Alex J. Van der Eb