Abstract: Methods of stimulating a target deep brain region using multiple Transcranial Magnetic Stimulation (TMS) electromagnets positioned over a predetermined cortical regions each having a first-order connection to a target deep brain region and applying TMS so that the applied TMS induces spatial summation and thereby modulation of the target deep brain region.
Type:
Grant
Filed:
June 27, 2011
Date of Patent:
May 31, 2016
Assignees:
Rio Grande Neurosciences, Inc., The Board of Trustees of the Leeland Stanford Junior University
Abstract: Apparatus and methods according to the present invention preferably utilize electroosmotic pumps that are capable of generating high pressure and flow without moving mechanical parts and the associated generation of unacceptable electrical and acoustic noise, as well as the associated reduction in reliability. These electroosmotic pumps are preferably fabricated with materials and structures that improve performance, efficiency, and reduce weight and manufacturing cost relative to presently available micropumps. These electroosmotic pumps also preferably allow for control including venting or recapture of evolved gases and deposited materials, which may provide for long-term closed-loop operation. A gas permeable membrane removes and vents electrolytic gasses generated within the fluid chamber of the electroosmotic pump to ambient. A catalyst can be used to recombine electrolytic gases to form a vapor product that can be vented or condensed into a liquid state.
Type:
Grant
Filed:
October 16, 2002
Date of Patent:
November 14, 2006
Assignee:
The Board of Trustees of the Leeland Stanford Junior University
Abstract: Genetic material encoding p30 and B1 peptides of Toxoplasma gondii has been isolated and characterized. This genetic material allows the production of peptides for use in diagnosis or immunization or can itself be directly used in hybridization assays.
Type:
Grant
Filed:
January 14, 1994
Date of Patent:
May 13, 1997
Assignee:
The Board of Trustees of the Leeland Stanford Junior University
Inventors:
John C. Boothroyd, James L. Burg, Lloyd H. Kasper
Abstract: Temperature-sensitive transducers and other circuitry are manufactured by an electrochemical post-processing etch on an integrated circuit fabricated using a conventional CMOS process. Tetramethyl ammonium hydroxide or another anisotropic etchant having similar characterisics is used to selectively etch exposed front-side regions of a p-type silicon substrate, leaving n-type wells suspended from oxide beams. Circuits in the n-wells are thermally and electrically insulated from the substrate.
Type:
Grant
Filed:
October 11, 1994
Date of Patent:
February 4, 1997
Assignee:
The Board of Trustees of the Leeland Stanford Junior University