Abstract: The present invention provides a biomolecular carrier of pharmaceuticals, comprising: a biomolecule carrier bearing molecules that bind to a cellular adhesion molecule expressed on endothelial cell; and a pharmaceutical. The present invention also provides a method of treating a pathophysiological state in an individual in need of such treatment, comprising the steps of: irradiating a target tissue or organ in said individual; and administering to said individual the biomolecular carrier disclosed herein.
Type:
Grant
Filed:
October 12, 2001
Date of Patent:
February 27, 2007
Assignees:
The University of Tennessee Research Corporation, The Board of Trustess of Ohio University