Abstract: A binary code similarity detection system that compares a target binary code to a source code by comparing the target binary code to a comparing binary generated by compiling the source code. Rather than using a comparing binary generated using a random or fixed compiling configuration, the system identifies the compiling configuration of the target binary code and compares the target binary code to a comparing binary generated using the same compiling configuration as the target binary code. The compiling configuration of the target binary code may be identified by a neural network (e.g., a graph attention network trained on attributed function call graphs of binary codes with known compiling configurations). The target binary code and the comparing binary may be compared using a graph neural network (e.g., a graph triplet loss network) that compares attributed control flow graphs of the of the target binary code and the comparing binary.

Abstract: An integrated photonics computing system implements a residue number system (RNS) to achieve orders of magnitude improvements in computational speed per watt over the current state-of-the-art. RNS and nanophotonics have a natural affinity where most operations can be achieved as spatial routing using electrically controlled directional coupler switches, thereby giving rise to an innovative processing-in-network (PIN) paradigm. The system provides a path for attojoule-per-bit efficient and fast electro-optic switching devices, and uses them to develop optical compute engines based on residue arithmetic leading to multi-purpose nanophotonic computing.

Abstract: A system for defending against a side channel attack. The system includes a reuse distance buffer configured to measure one or more reuse distances for a microarchitecture block according to information of marker candidates and information of target events of a microarchitecture block; and a defense actuator configured to determine existence of a side channel attack in the microarchitecture block according to the one or more reuse distances for the microarchitecture block.

Abstract: A system and method for defense against cache timing channel attacks using cache management hardware is provided. Sensitive information leakage is a growing security concern exacerbated by shared hardware structures in computer processors. Recent studies have shown how adversaries can exploit cache timing channel attacks to exfiltrate secret information. To effectively guard computing systems against such attacks, embodiments disclosed herein provide practical defense techniques that are readily deployable and introduce only minimal performance overhead. In this regard, a new protection framework against cache timing channel attacks is provided herein by leveraging commercial off-the-shelf (COTS) hardware support in processor caches, including last level caches (LLC), for cache monitoring and partitioning. This framework applies signal processing techniques on per-domain cache occupancy data to identify suspicious application contexts.

Abstract: This disclosure provides methods of treating obesity, nonalcohol-related fatty liver disease, nonalcoholic steatohepatitis, or hepatocellular cancer in a subject in need thereof, the method comprising administering a therapeutically effective amount of at least one siRNA molecule targeting SPTBN1.

Abstract: A system includes a log receiving module, an authentication graph module, a sampling module, an embedding module, a training module, a link prediction module, and an anomaly detection module. The log receiving module is configured to receive a first plurality of network-level authentication logs. The authentication graph module is configured to generate an authentication graph. The sampling module is configured to generate a plurality of sequences. The embedding module is configured to tune a plurality of node embeddings according to the plurality of sequences. The training module is configured to train a link predictor according to the plurality of node embeddings and ground-truth edge information from the authentication graph. The link prediction module is configured to apply the link predictor to performs a link prediction. The anomaly detection module is configured to perform anomaly detection according to the link prediction.

Abstract: Carbon-doped graphitic carbon nitride (g-C3N4) compositions are synthesized from the chemical precursors melamine, cyanuric acid and barbituric acid. Phosphorus-doped g-C3N4 compositions are synthesized from the chemical precursors melamine, cyanuric acid and etidronic acid. Carbon- and phosphorus-doped g-C3N4 compositions, when in the presence of UV or visible light, can be used in water treatment systems to photocatalytically degrade persistent organic micropollutants such as pharmaceuticals and personal care products (PPCPs), endocrine disrupting compounds (EDCs), pesticides, and herbicides. Carbon- and phosphorus-doped g-C3N4 compositions can also be applied to surfaces of household and public items to kill protozoa, eukaryotic parasites, algal pathogens, bacteria, fungi, prions, viruses, or other microorganisms, preventing the transfer thereof between users.

Abstract: The present disclosure provides signal transducer and activator of transcription (STAT)-activated macrophages, compositions comprising STAT-activated macrophages, methods of making STAT-activated macrophages, and methods of treating diseases, e.g., cancer, by administering a therapeutically effective amount of STAT-activated macrophages.

Abstract: Among the various aspects of the present disclosure is the provision of devices, systems, and methods for tracking the positions and orientations of at least one bone screw implanted within a surgical site. The disclosed device includes an extension that includes an extension base configured to couple to the bone screw, a marker arm coupled at one end to the extension base in a hinged arrangement, and an optical marker attached to a free end of the marker arm opposite the hinged attachment. The optical marker includes a pair of lenticular arrays in a coplanar arrangement in which the major axes of the lenticular arrays are mutually perpendicular. Each lenticular array is configured to display different hues at different viewing angles. The disclosed method includes transforming a single image of a surgical site containing at least one bone screw and extension into the global positions of each bone screw based on the pixel positions and hues corresponding to the lenticular arrays of each optical marker.

Abstract: Solutions having a solvent and a cold atmospheric plasma dissolved in the solvent are described. Methods and systems of forming cold atmospheric plasma (CAP)-containing solutions are also described. A system for producing (CAP)-containing solutions includes a gas source; a plasma generating device having a hollow body fluidically coupled with the gas source, a closed proximal end and an open distal end, the hollow body receiving gas from the gas source, and at least one electrode in or about the hollow body and ionizing the gas to discharge a cold atmospheric plasma (CAP) from the open distal end; and a container for housing a fluid, the open distal end of the plasma generating device in fluid communication with an inner portion of the container. CAP-containing solutions can be used in treatment of cancer cells, infected tissue sterilization, microorganism inactivation, promotion of wound healing, skin regeneration, and blood coagulation, and teeth bleaching/whitening.

Abstract: A thruster has a first stage and a second stage. The first stage is a plasma source that outputs a plasma. The second stage is an accelerator. In one embodiment, the second stage is a plasma accelerator that accelerates the plasma. In another embodiment, the second stage is an ion accelerator that accelerates the ions from the plasma.

Abstract: A digital-to-analog converter has a first interface coupled to a second interface through one or more modulation circuits. The circuits include a first coupler connected to the first interface; a first waveguide with a first lead connected to the first coupler, a first end, and a first length running therebetween. The first lead and the first end are coupled by a first switch. The circuits also include: a second coupler connected to the first interface; a second waveguide having a second lead connected to the second coupler, a second end, and a second length running therebetween, the second lead and the second end coupled by a second switch along the second length; and an optical combiner connected to the ends of the waveguides. The second interface is connected to the optical combiner of the modulation circuits. Output from the second interface is an optical signal capable of carrying binary information.

Abstract: The present disclosure relates to antibodies binding to tumor discoidin domain receptor 1 (DDR1) and the uses of the antibodies in detecting and treating cancer.

Abstract: An accelerator for modern convolutional neural networks applies the Winograd filtering algorithm in a wavelength division multiplexing integrated photonics circuit modulated by a memristor-based analog memory unit.

Abstract: A medical apparatus for an organ has a substrate that conforms to a shape of the organ, and a plurality of processing units connected to the substrate and distributed throughout the substrate. Each of the processing units has a sensor, processing device and actuator. The sensor senses a condition of the organ and provides a sensed signal. The processing device receives the sensed signal from said sensor, analyzes the sensed signal and provides a control signal. The actuator applies an output pulse to the organ in response to the control signal from the processing device.

Abstract: The disclosure provides modified NK cells and pharmaceutical compositions comrpsing the same. The disclosure also provides methods of treating cancer using the same.

Abstract: Bio-photonic devices or target cells and cell cultures including bio-photonic devices and target cells are provided. Methods of preparing cell cultures including bio-photonic devices and target cells are also provided. Methods of analyzing the electrophysiology of target cells using the cell cultures are provided. Systems for analyzing the electrophysiology of target cells are also provided.

Abstract: Biofunctionalized nanocomposites comprised of a core nanoparticle formed of Prussian blue materials, a shell obtained by partially or completely encapsulating the Prussian blue core with a biocompatible coating, and at least one biomolecule attached to, or absorbed to, the biocompatible coating and uses thereof.

Abstract: Methods and kits for diagnosing and/or treating a lower respiratory infection in a subject include obtaining a biological sample from the subject; detecting RNA expression levels of one or more biomarkers in the biological sample and comparing the expression levels of the one or more three biomarkers to at least one invariant control marker wherein an increase or decrease in the level of expression of the one or more biomarkers as compared to the at least one invariant control marker is indicative of a lower respiratory infection.

Abstract: Effective management of cloud computing service levels (e.g. availability, performance, security) and financial risk is dependent on the cloud service provider's (CSP's) capability and trustworthiness. The invention applies industry cloud service level agreements (SLAs) with statistical and machine learning models for assessing CSPs and cloud services, and predicting performance and compliance against service levels. Cloud SLAs (ISO/IEC, EC, ENISA), cloud security requirements and compliance (CSA CCM, CAIQ), along with CSP performance (SLAs, cloud services) are analyzed via Graph Theory analysis and MCDA AHP to calculate CSP trustworthiness levels. CSP trustworthiness levels are input with CSP SLA content, cloud service performance measurements and configuration parameters into machine learning Regression analysis models to predict CSP cloud service performance and cloud SLA compliance, and enable model analysis and comparison.