Patents Assigned to THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETAR
  • ADENOVIRUSES AND THEIR USE
    Publication number: 20160068917
    Abstract: Baboon Adenovirus (BaAdV)-2/4 and BaAdV-3 are disclosed herein. BaAdV-2/4 and BaAdV-3 polynucleotide, polypeptides and antibodies that specifically bind BaAdV-2/4 and/or BaAdV-3 are disclosed. Methods are disclosed for detecting BaAdV-2/4 and BaAdV-3. Methods are also disclosed for treating, preventing, and inducing an immune response to BaAdV-2/4 and/or BaAdV-3. Kits are also provided.
    Type: Application
    Filed: November 17, 2015
    Publication date: March 10, 2016
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, TEXAS BIOMEDICAL RESEARCH INSTITUTE, THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETAR
    Inventors: Charles Chiu, Jean Patterson, Mary Michelle Leland, Kenneth Dee Carey, Dean Ehrdman
  • COMPOSITIONS AND METHODS FOR DENGUE VIRUS CHIMERIC CONSTRUCTS IN VACCINES
    Publication number: 20140302088
    Abstract: Embodiments herein report compositions, uses and manufacturing of dengue virus constructs and live attenuated dengue viruses. Some embodiments concern a composition that includes, but is not limited to, a tetravalent dengue virus composition. In certain embodiments, compositions can include constructs of one or more serotypes of dengue virus, such as dengue-1 (DEN-1) virus, dengue-2 (DEN-2) virus, dengue-3 (DEN-3) or dengue-4 (DEN-4) virus constructs. In other embodiments, constructs disclosed herein can be combined in a composition to generate a vaccine against more one or more dengue virus constructs that may or may not be subsequently passaged in mammalian cells.
    Type: Application
    Filed: March 13, 2014
    Publication date: October 9, 2014
    Applicants: The Government of the United States of America as Represented by the Secretar, INVIRAGEN, INC.
    Inventors: Daniel T. Stinchcomb, Claire Y Huang, Richard M Kinney, Jill A Livengood
  • COMPOSITE REPAIR RESINS CONTAINING MINIMAL HAZARDOUS AIR POLLUTANTS AND VOLATILE ORGANIC COMPOUND
    Publication number: 20110257320
    Abstract: The present invention relates to a composition and method for fabricating composite resins that produce either reduced or zero volatile organic compound (VOC) and zero hazardous air pollutant (HAP) emissions. The non-volatile reactive diluents of the composite resin, fatty acid monomers, enhance the stability, shelf-life, flexibility and strength of the composite resin. The resins incorporating fatty acid monomers may be used to repair military equipment or for any commercial repair purposes.
    Type: Application
    Filed: March 21, 2007
    Publication date: October 20, 2011
    Applicants: DREXEL UNIVERSITY, THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETAR
    Inventors: JOHN JOSEPH LA SCALA, GIUSEPPE RAFFAELLO PALMESE, JAMES MATTHEW SANDS
  • ADENOVIRAL VECTOR-BASED MALARIA VACCINES
    Publication number: 20080248060
    Abstract: The invention provides a method of inducing an immune response against malaria in a mammal. The method comprises intramuscularly administering to a mammal a composition comprising a pharmaceutically acceptable carrier and either or both of (a) a first adenoviral vector comprising a nucleic acid sequence encoding a P. falciparum circumsporozoite protein (CSP) operably linked to a human CMV promoter, and/or (b) a second adenoviral vector comprising a nucleic acid sequence encoding a P. falciparum apical membrane antigen 1 (AMA-1) antigen operably linked to a human CMV promoter.
    Type: Application
    Filed: January 9, 2008
    Publication date: October 9, 2008
    Applicants: GENVEC, INC., THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETAR
    Inventors: Joseph T. Bruder, C. Richter King, Thomas Richie, Keith Limbach, Denise Louis Doolan