Patents Assigned to The State of Oregon acting by and through the State of Board of Higher Education on behalf of the Unviersity of Oregon
  • Fluorescent protein sensors for measuring the pH of a biological sample
    Patent number: 6150176
    Abstract: Disclosed are fluorescent protein sensors for measuring the pH of a sample, nucleic acids encoding them, and methods of use. The preferred fluorescent protein sensors are variants of the green fluorescent protein (GFP) from Aequorea victoria. Also disclosed are compositions and methods for measuring the pH of a specific region of a cell, such as the mitochondrial matrix or the Golgi lumen.
    Type: Grant
    Filed: October 13, 1998
    Date of Patent: November 21, 2000
    Assignees: The Regents of the University of California, The State of Oregon acting by and through the State of Board of Higher Education on behalf of the Unviersity of Oregon
    Inventors: Roger Y. Tsien, Juan Llopis, Rebekka M. Wachter, S. James Remington