Abstract: The present disclosure describes for at least two zones of selective thermal therapy of the body. Three-port extracorporeal circuits are described that can be used to establish at least two zones of selective thermal therapy of the body. The example three-port extracorporeal circuit includes a branching section that provides for setting the temperature of blood injected into two different portions of the body at differing temperature levels, to provide. at least two zones of selective thermal therapy.

Abstract: The present disclosure describes flow stagnation control components that allow improved flow control in systems including injection members, while also limiting the creation of regions of little to no flow in the vasculature, resulting in low flow zones or dead zones. The flow stagnation control components can be formed as an imposed minimum conductance component or a controlled flow partitioning system.

Abstract: The present disclosure describes effector deployment systems and devices that can be coupled adjunctively to a shaft of a concentric cylinder system, to provide additional functionality during intravascular procedures.

Abstract: The example systems, apparatus and methods use a local perfusion extracorporeal circuit (LPEC) for perfusing a local target region of a body, with a systemic perfusion extracorporeal circuit (SPEC) coupled to the core region of the vasculature using a peripheral placed loop to the body, and a control procedure to cause the local target region of the body to be at a specified pattern of temperature values that are different than the temperature of the core of the body.

Abstract: Methodologies and systems are provided for an operating location logging system for use in connection with a complex medical procedure. Example operating location logging systems include an image recording system configured to capture at least one image of a portion of at least one of a data recording object or a display of an instrument, and a console including at least one processing device. The at least one processing device is programmed to receive image data, representative of a plurality of images, that is transmitted using a data transmission component of the image recording system, and collect and/or compute medical data in connection with the complex medical procedure.

Abstract: The present disclosure describes flow stagnation control components that allow improved flow control in systems including injection members, while also limiting the creation of regions of little to no flow in the vasculature, resulting in low flow zones or dead zones. The flow stagnation control components can be formed as an imposed minimum conductance component or a controlled flow partitioning system.

Abstract: The present disclosure describes for at least two zones of selective thermal therapy of the body. Three-port extracorporeal circuits are described that can be used to establish at least two zones of selective thermal therapy of the body. The example three-port extracorporeal circuit includes a branching section that provides for setting the temperature of blood injected into two different portions of the body at differing temperature levels, to provide at least two zones of selective thermal therapy.

Abstract: The present disclosure describes flow stagnation control components that allow improved flow control in systems including injection members, while also limiting the creation of regions of little to no flow in the vasculature, resulting in low flow zones or dead zones. The flow stagnation control components can be formed as an imposed minimum conductance component or a controlled flow partitioning system.

Abstract: The example systems, apparatus and methods use a local perfusion extracorporeal circuit (LPEC) for perfusing a local target region of a body, with a systemic perfusion extracorporeal circuit (SPEC) coupled to the core region of the vasculature using a peripheral placed loop to the body, and a control procedure to cause the local target region of the body to be at a specified pattern of temperature values that are different than the temperature of the core of the body.

Abstract: The example systems, apparatus and methods use a local perfusion extracorporeal circuit (LPEC) for perfusing a local target region of a body, with a systemic perfusion extracorporeal circuit (SPEC) coupled to the core region of the vasculature using a peripheral placed loop to the body, and a control procedure to cause the local target region of the body to be at a specified pattern of temperature values that are different than the temperature of the core of the body.

Abstract: The present disclosure describes flow stagnation control components that allow improved flow control in systems including injection members, while also limiting the creation of regions of little to no flow in the vasculature, resulting in low flow zones or dead zones. The flow stagnation control components can be formed as an imposed minimum conductance component or a controlled flow partitioning system.

Abstract: The present disclosure describes for at least two zones of selective thermal therapy of the body. Three-port extracorporeal circuits are described that can be used to establish at least two zones of selective thermal therapy of the body. The example three-port extracorporeal circuit includes a branching section that provides for setting the temperature of blood injected into two different portions of the body at differing temperature levels, to provide at least two zones of selective thermal therapy.

Abstract: The present disclosure describes quantification of the flow conductance in a region of the vasculature using a catheter member coupled to at least two pressure sensors. Data from measurements of the pressure at known, controlled patterns of flow rates at the catheter member can be used to compute values of the flow conductance for the regions of the vasculature.

Abstract: The example systems, apparatus and methods use a local perfusion extracorporeal circuit (LPEC) for perfusing a local target region of a body, with a systemic perfusion extracorporeal circuit (SPEC) coupled to the core region of the vasculature using a peripheral placed loop to the body, and a control procedure to cause the local target region of the body to be at a specified pattern of temperature values that are different than the temperature of the core of the body.

Abstract: The present invention discloses a gamboge acid cyclization analogs, their preparation methods and applications by semi-synthesis with the following structural formula I-III: Where ring A, ring B or/and ring C is 4-10 membered saturated or/and unsaturated aliphatic ring aliphatic heterocycle or aryl heterocycle. R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 or/and R12 is, independently at each occurrence, optionally substituted substituent of glycosyl, multi-hydroxyl, amino acid, acyloxy, phosphoric acid oxy, sulfonyloxy, alkoxy, aryloxy, heterocyclic oxy, thiol, aliphatic or cyclic group containing oxygen, sulfur, nitrogen or phosphorus, one of the substituents or combinations thereof. The present invention has antitumor activity management, antiviral, antibacterial and antifungal activity management, as anti-tumor, anti-viral, immune, antibacterial and antifungal agents, with other known anti-tumor, anti-viral, immune, together with the application of antibacterial and antifungal.

Abstract: A high-frequency pneumatic loudspeaker for sound broadcasting is provided, and comprises a housing, silencer exhaust holes, air inlet port, supporting plate, throat canal, central cone, annular nozzle, obstructing ring, and a voice coil and leads. Lower and an upper press plates hold the obstructing ring and the voice coil in position, a magnet having inner and outer magnetic poles is connected therewith, wherein a small gap exists between the obstructing ring and the end of the annular nozzle. This provides the advantages of both air passage area modulation by a sleeve air valve and airstream direction modulation by jet obstruction, reduces airstream consumption, improves air-sound conversion efficiency, and improves structures of an annular air flow-splitter, voice coil and leads. A cooling system is provided to improve high-frequency modulation sensitivity, operation stability, and/or extended fault-free operation time.

Abstract: A cable guard eliminator for a compound bow comprising a first limb and a second limb and having a bowstring and at least one cable strung between first and second connecting elements respectively mounted near outer ends of the first and second limbs. The cable guard eliminator comprises a first portion from which the cable extends to the first connecting element, a second portion from which the cable extends to the second connecting element, and, an intermediate portion defining a deflection area between the first end and the second end. The deflection area has a length in a direction generally parallel to the cable at least as long as a range of motion of the cable, such that at least some portion of the deflection area remains aligned with an arrow path throughout drawing and release of the bowstring.

Abstract: The present invention belongs to the field of loudspeaker and relates to directional sound wave radiator comprising a sound transmission duct, a reverser, an annular director, a parabolic reflector, and a straight tubular loudspeaker cylinder. The sound transmission duct is mounted substantially coaxially with said parabolic reflector. The straight tubular loudspeaker cylinder is connected to said parabolic reflector. The reverser is provided inside said straight tubular loudspeaker cylinder and at the outlet end of said sound transmission duct; the outlet end of said reverser has an annular section, which is substantially perpendicular to the axis of said parabolic reflector and is positioned substantially at the focus of said parabolic reflector. The annular director is mounted around said sound transmission duct and at the outlet end of said reverser to define an annular shape of the outlet end of said reverser.

Abstract: The invention provides a portable bow press and a limb connector therefor, for use with a bow comprising a pair of resilient limbs that extend outwardly from a handle. The bow press is used to force the outer ends of the limbs together, thereby releasing tension on the bow string and/or cable. The user is then able to remove, replace or repair the bow string or cable while the bow press holds the bow in position. The bow press may comprise two limb connectors which hold the bow press in place. Each limb connector may comprise an outer peg and an inner peg, which are used to couple the limb connector to a bow limb.

Abstract: The invention provides a portable bow press and a limb connector therefor, for use with a bow comprising a pair of resilient limbs that extend outwardly from a handle. The bow press is used to force the outer ends of the limbs together, thereby releasing tension on the bow string and/or cable. The user is then able to remove, replace or repair the bow string or cable while the bow press holds the bow in position. The bow press may comprise two limb connectors which hold the bow press in place. Each limb connector may comprise an outer peg and an inner peg, which are used to couple the limb connector to a bow limb.