Patents Assigned to The Texas & M University System College
  • Method to produce granulocyte colony stimulating factor from immortalized avian T lymphocytes to produce immortalized cells
    Patent number: 5891443
    Abstract: Immortal avian T lymphocyte cell lines which produce and secrete immune lymphokines are disclosed. These cell lines may be produced from T cells recovered from fowl which have been hyperimmunized in vivo. The activated T cells are first exposed in vitro to a mitogen effective for secondary stimulation thereof, and then virally transformed to produce an immortal cell line. When cultured in vitro, the cell lines produce and secrete immune lymphokines which may be administered to fowl to increase their resistance to infections.
    Type: Grant
    Filed: September 15, 1997
    Date of Patent: April 6, 1999
    Assignees: The United States of America as represented by the Secretary of Agriculture, The Texas & M University System College
    Inventors: Michael H. Kogut, John R. DeLoach, Larry H. Stanker, Rita B. Moyes, Billy M. Hargis